LU80476A1 - Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation - Google Patents

Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation

Info

Publication number
LU80476A1
LU80476A1 LU80476A LU80476A LU80476A1 LU 80476 A1 LU80476 A1 LU 80476A1 LU 80476 A LU80476 A LU 80476A LU 80476 A LU80476 A LU 80476A LU 80476 A1 LU80476 A1 LU 80476A1
Authority
LU
Luxembourg
Prior art keywords
guanidines
quinolyl
inflammatory
useful
new
Prior art date
Application number
LU80476A
Other languages
English (en)
French (fr)
Inventor
Rachlin Schneur
Arrigoni-Martelli Edoardo
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of LU80476A1 publication Critical patent/LU80476A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
LU80476A 1977-11-07 1978-11-06 Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation LU80476A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4616677 1977-11-07

Publications (1)

Publication Number Publication Date
LU80476A1 true LU80476A1 (fr) 1979-06-15

Family

ID=10440127

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80476A LU80476A1 (fr) 1977-11-07 1978-11-06 Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation

Country Status (24)

Country Link
US (1) US4293549A (no)
JP (1) JPS5473784A (no)
AT (1) AT366368B (no)
AU (1) AU517670B2 (no)
BE (1) BE871807A (no)
CA (1) CA1120929A (no)
CH (1) CH645354A5 (no)
DE (1) DE2847792A1 (no)
DK (1) DK153950C (no)
ES (1) ES474900A1 (no)
FI (1) FI69463C (no)
FR (1) FR2407930A1 (no)
GR (1) GR65010B (no)
IE (1) IE47458B1 (no)
IT (1) IT1100075B (no)
LU (1) LU80476A1 (no)
NL (1) NL7811035A (no)
NZ (1) NZ188770A (no)
PH (1) PH16296A (no)
PT (1) PT68750A (no)
SE (1) SE446267B (no)
SU (1) SU828967A3 (no)
YU (1) YU41129B (no)
ZA (1) ZA786175B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306846B1 (en) * 1972-05-31 2001-10-23 John R. J. Sorenson Anti-inflammatory and anti-ulcer compounds and process
IT1205640B (it) * 1983-04-06 1989-03-23 Yason Srl Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
US4563460A (en) * 1984-01-13 1986-01-07 William H. Rorer, Inc. Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions
HU195487B (en) * 1985-06-04 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for producing quinoline derivatives
ES2031514T3 (es) * 1986-08-29 1992-12-16 Pfizer Inc. 2-guanidino-4-ariltiazoles para el tratamiento de ulceras pepticas.
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives
EP0928793B1 (en) * 1998-01-02 2002-05-15 F. Hoffmann-La Roche Ag Thiazole derivatives
AU754716B2 (en) * 1998-03-26 2002-11-21 Japan Tobacco Inc. Amide derivatives and nociceptin antagonists
JP2003513064A (ja) * 1999-11-05 2003-04-08 ユニバーシティ カレッジ ロンドン 可溶性グアニル酸シクラーゼのアクチベーター
WO2004063181A1 (en) * 2003-01-03 2004-07-29 Genzyme Corporation Urea derivatives and their use as anti-inflammatory agents
CA2511970C (en) * 2003-01-14 2012-06-26 Cytokinetics, Inc. Urea derivatives useful in the treatment of heart failure
GB0404434D0 (en) 2004-02-27 2004-03-31 Novartis Ag Organic compounds
US9296697B2 (en) * 2005-08-24 2016-03-29 Abbott Laboratories Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-HT5-receptors
WO2023003497A1 (ru) * 2021-07-23 2023-01-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Соединения с лизосомотропной и противовирусной активностью

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889282A (en) * 1957-05-07 1962-02-14 Air Reduction Preparation of hexafluorodiethyl ether and medicinal compositions containing it
GB889262A (en) * 1959-07-03 1962-02-14 Ciba Ltd Quinoline compounds
US3159676A (en) * 1962-02-07 1964-12-01 Smith Kline French Lab Naphthyl containing guanidines
US3852293A (en) 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US4000279A (en) * 1974-10-29 1976-12-28 Armour Pharmaceutical Company Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same

Also Published As

Publication number Publication date
ES474900A1 (es) 1980-04-16
FI69463C (fi) 1986-02-10
IE782084L (en) 1979-05-07
US4293549A (en) 1981-10-06
FR2407930A1 (fr) 1979-06-01
FI783327A (fi) 1979-05-08
JPS6348873B2 (no) 1988-09-30
DE2847792C2 (no) 1988-02-04
BE871807A (fr) 1979-05-07
FI69463B (fi) 1985-10-31
CA1120929A (en) 1982-03-30
NL7811035A (nl) 1979-05-09
YU257578A (en) 1983-01-21
DK153950B (da) 1988-09-26
DK153950C (da) 1989-02-20
SU828967A3 (ru) 1981-05-07
JPS5473784A (en) 1979-06-13
YU41129B (en) 1986-12-31
DK493378A (da) 1979-05-08
ATA773278A (de) 1981-08-15
GR65010B (en) 1980-06-12
CH645354A5 (de) 1984-09-28
SE7811457L (sv) 1979-05-08
SE446267B (sv) 1986-08-25
PH16296A (en) 1983-09-05
IT1100075B (it) 1985-09-28
NZ188770A (en) 1984-07-31
IT7829514A0 (it) 1978-11-07
AU4137678A (en) 1979-05-17
FR2407930B1 (no) 1983-03-18
IE47458B1 (en) 1984-03-21
PT68750A (en) 1978-12-01
ZA786175B (en) 1979-10-31
DE2847792A1 (de) 1979-05-10
AU517670B2 (en) 1981-08-20
AT366368B (de) 1982-04-13

Similar Documents

Publication Publication Date Title
BE836885A (fr) Nouvelles cyanoguanidylpyridines, utiles notamment comme hypotenseurs,et leur procede de preparation
FR2497203B1 (fr) Nouveaux 7-oxa-bicycloheptanes et -bicycloheptenes utiles notamment comme agents cardiovasculaires, et leur procede de preparation
FR2338928A1 (fr) Nouvelles n-phenyl-n'-benzoylurees, leur procede de preparation et leur application comme insecticides
BE866031A (fr) Nouveaux 2-(2,2-diarylalkyl)-1-azabicyclo (2,2,2)octanes, utiles notamment comme antidiarrheiques, et leur procede de preparation
BE846452A (fr) Nouvelles pyrimidones, leur procede de preparation et leur applicationtherapeutique
BE847090A (fr) 15-steroides, et leur procede de preparation
LU80476A1 (fr) Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation
FR2317934A1 (fr) Nouveaux 16-dehydro-androstanes, utiles notamment en dermatologie, et leur procede de preparation
FR2319343A1 (fr) Nouvelles guanidines, leur procede de preparation et leur application
BE858024A (fr) Nouvelles benzylurees substituees, leur procede de preparation et leur application comme insecticides
FR2301521A1 (fr) Nouvelles n-acyl-n-norsalutaridines et leur procede de preparation
BE826851A (fr) Nouvelles alkoxycarbonylphenylurees, leur procede de preparation et leur application comme herbicides
FR2342734A1 (fr) Nouvelles cephalosporines, utiles notamment comme antibacteriens, et leur procede de preparation
BE885946A (fr) Nouvelles pyridothienotriazines et leur procede de preparation
FR2348920A1 (fr) Nouveaux triazapentadienes,leur procede de preparation et leur application comme acaricides
FR2409996B1 (fr) 05-epi-prostacycline et analogues, utiles notamment comme agents antithrombotiques et thrombolytiques et leur procede de preparation
FR2320746A1 (fr) Nouveau thiopyranno(4,3-c)pyrasoles, utiles notamment comme anti-inflammatoires et leur procede de preparation
BE885039A (fr) Nouvelles 5-(2-chlorophenyl)-6h-1,3,4-thiadiazine-2-amines, utiles notamment comme anticonvulsivants, et leur procede de preparation
FR2340309A1 (fr) Nouveaux imidazolyl-o,n-acetals acyles, leur procede de preparation et leur application comme fongicides
BE868027A (fr) Nouvelles pyridazinylhydrazones et leur procede de preparation
FR2316937A1 (fr) Nouveaux 9-hydroxy-7,8,9,10-tetrahydro-6h-dibenzo (b)-(d)pyrannes et pyrannones, utiles notamment comme analgesiques, et leur procede de preparation
BE869481A (fr) Procede de preparation de pyridazinones-3, nouvelles pyridazinones-3 et leur utilisation comme herbicides
FR2327244A1 (fr) Pyrazolyltriazoles utiles comme herbicides et leur procede de preparation
FR2348217A1 (fr) Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation
FR2303548A1 (fr) Nouveaux carbamates de 2-halogenoergolines et 2-halogenoergolenes, utiles notamment comme vasodilatateurs, et leur procede de preparation