LU80124A1 - Procede de production de derives 1-n-alkyles de la kanamycine - Google Patents

Procede de production de derives 1-n-alkyles de la kanamycine Download PDF

Info

Publication number
LU80124A1
LU80124A1 LU80124A LU80124A LU80124A1 LU 80124 A1 LU80124 A1 LU 80124A1 LU 80124 A LU80124 A LU 80124A LU 80124 A LU80124 A LU 80124A LU 80124 A1 LU80124 A1 LU 80124A1
Authority
LU
Luxembourg
Prior art keywords
group
kanamycin
formula
acetyl
formyl
Prior art date
Application number
LU80124A
Other languages
English (en)
French (fr)
Inventor
M Thomas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of LU80124A1 publication Critical patent/LU80124A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
LU80124A 1977-08-18 1978-08-17 Procede de production de derives 1-n-alkyles de la kanamycine LU80124A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3480877 1977-08-18
GB3480877 1977-08-18

Publications (1)

Publication Number Publication Date
LU80124A1 true LU80124A1 (fr) 1980-04-21

Family

ID=10370176

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80124A LU80124A1 (fr) 1977-08-18 1978-08-17 Procede de production de derives 1-n-alkyles de la kanamycine

Country Status (24)

Country Link
US (1) US4178437A (fi)
JP (1) JPS5459256A (fi)
AR (1) AR218324A1 (fi)
AT (1) AT360154B (fi)
BE (1) BE869761A (fi)
CA (1) CA1106842A (fi)
CS (1) CS201512B2 (fi)
DD (2) DD139582A5 (fi)
DE (1) DE2835759A1 (fi)
DK (1) DK308878A (fi)
EG (1) EG13472A (fi)
ES (2) ES472657A1 (fi)
FI (1) FI782497A (fi)
FR (1) FR2400523A1 (fi)
GR (1) GR70241B (fi)
IE (1) IE47150B1 (fi)
IT (1) IT1098281B (fi)
LU (1) LU80124A1 (fi)
NL (1) NL7808566A (fi)
NO (1) NO782796L (fi)
PL (2) PL114720B1 (fi)
PT (1) PT68427A (fi)
SE (1) SE7808702L (fi)
SU (1) SU873889A3 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493831A (en) * 1982-10-25 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
AU2008326297B2 (en) * 2007-11-21 2012-11-08 Cipla USA, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE630462A (fi) * 1962-04-03
JPS5644076B2 (fi) * 1973-07-12 1981-10-16
US4029882A (en) * 1974-03-19 1977-06-14 Schering Corporation Selective acylation of the C-1 amino group of aminoglycoside antibiotics
US4044123A (en) * 1975-05-02 1977-08-23 Schering Corporation 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their use as antibacterial agents and compositions useful therefor
NZ184213A (en) * 1976-06-16 1980-05-27 Pfizer 2-deoxystreptamine aminoglycosides and antibacterial pharmaceutical compositions

Also Published As

Publication number Publication date
GR70241B (fi) 1982-09-01
NO782796L (no) 1979-02-20
ES472657A1 (es) 1979-10-16
NL7808566A (nl) 1979-02-20
CS201512B2 (en) 1980-11-28
AT360154B (de) 1980-12-29
BE869761A (fr) 1979-02-16
IT1098281B (it) 1985-09-07
PT68427A (en) 1978-09-01
PL209082A1 (fi) 1980-01-02
SE7808702L (sv) 1979-02-19
IT7826812A0 (it) 1978-08-17
JPS5459256A (en) 1979-05-12
IE47150B1 (en) 1983-12-28
FR2400523A1 (fr) 1979-03-16
IE781653L (en) 1979-02-18
DD148220A5 (de) 1981-05-13
DD139582A5 (de) 1980-01-09
EG13472A (en) 1981-12-31
FI782497A (fi) 1979-02-19
ATA590278A (de) 1980-05-15
CA1106842A (en) 1981-08-11
AR218324A1 (es) 1980-05-30
DK308878A (da) 1979-02-19
ES479667A1 (es) 1979-08-01
PL114720B1 (en) 1981-02-28
SU873889A3 (ru) 1981-10-15
PL114954B1 (en) 1981-03-31
DE2835759A1 (de) 1979-03-08
US4178437A (en) 1979-12-11

Similar Documents

Publication Publication Date Title
CA2356942C (en) Preparation of iodixanol
FR2514350A1 (fr) N-(4- (3-aminopropyl) aminobutyl)-2-(o-guanidino (acide gras)amido)-ethanamides substitues en position 2 et leurs sels, procede pour leur preparation et leur application therapeutique
EP0340064B1 (fr) Benzodiazépines, leur procédé et intermédiaires de préparation et leurs applications en thérapeutique
FR2515184A1 (fr) Syntheses de derives de la codeine et autres 3-o-alkylmorphines et composes intermediaires utilises
LU80124A1 (fr) Procede de production de derives 1-n-alkyles de la kanamycine
CH622528A5 (en) Process for the preparation of aminoglycoside antibiotics
CH618706A5 (fi)
JPH0212958B2 (fi)
IL156463A (en) Process for the preparation of 25-cyclohexyl-23,22-dihydro-5-oxoawermectin 1B
US4003922A (en) Synthesis of cis-1,4-cyclohexadiene dioxide
DE2617597A1 (de) Verfahren zur herstellung von alpha-substituierten 1-n-(w-aminoacyl)- 3'-deoxyribostamycinen
US4169939A (en) Processes for the production of 3',4'-dideoxykanamycin b
Pelyvás et al. Synthesis of N-trifluoroacetyl-l-acosamine, N-trifluoroacetyl-l-daunosamine, and their 1-thio analogs
FR2766188A1 (fr) Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes
US4101556A (en) Total synthesis of 2,5-dideoxystreptamines
NL8520047A (nl) Werkwijze voor het bereiden van n-acylphenylalanines.
DE69708950T2 (de) Verfahren zur Herstellung von 2'-Deoxy-2'-Halocoformycin oder Stereoisomere davon
Valcavi et al. Chemical modifications in the tetracycline series
DE68928249T2 (de) Verfahren zur Trennung von Methylester von alpha-L-aspartyl-L-phenylalaninen
IE47709B1 (en) A process for the production of 4-aminobutyric acid or its derivatives
Limberg et al. Synthesis of modified aldonic acids and studies of their substrate efficiency for dihydroxy acid dehydratase (DHAD)
JPH10237013A (ja) 光学活性2−ベンジルコハク酸の製造法
EP0087654B1 (de) Verfahren zur Herstellung von 1-(4-Chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsäure
CA1129886A (fr) Procede de preparation de n-alcoylamino benzophenones
FR1464537A (fr) Nouveaux aminophénanthrènes et leur procédé de fabrication