CS201512B2 - Method of producing 1-n-alkyl-substituted derivatives of kanamycin - Google Patents

Method of producing 1-n-alkyl-substituted derivatives of kanamycin Download PDF

Info

Publication number
CS201512B2
CS201512B2 CS785377A CS537778A CS201512B2 CS 201512 B2 CS201512 B2 CS 201512B2 CS 785377 A CS785377 A CS 785377A CS 537778 A CS537778 A CS 537778A CS 201512 B2 CS201512 B2 CS 201512B2
Authority
CS
Czechoslovakia
Prior art keywords
group
kanamycin
formula
apos
formyl
Prior art date
Application number
CS785377A
Other languages
Czech (cs)
English (en)
Inventor
Michael B Thomas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS794190A priority Critical patent/CS201513B2/cs
Publication of CS201512B2 publication Critical patent/CS201512B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CS785377A 1977-08-18 1978-08-17 Method of producing 1-n-alkyl-substituted derivatives of kanamycin CS201512B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS794190A CS201513B2 (cs) 1977-08-18 1979-06-18 Zpasob výroby nových 6’-N-substituovaných-3-N-formyl- -kanamycinových derivátů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3480877 1977-08-18

Publications (1)

Publication Number Publication Date
CS201512B2 true CS201512B2 (en) 1980-11-28

Family

ID=10370176

Family Applications (1)

Application Number Title Priority Date Filing Date
CS785377A CS201512B2 (en) 1977-08-18 1978-08-17 Method of producing 1-n-alkyl-substituted derivatives of kanamycin

Country Status (24)

Country Link
US (1) US4178437A (fi)
JP (1) JPS5459256A (fi)
AR (1) AR218324A1 (fi)
AT (1) AT360154B (fi)
BE (1) BE869761A (fi)
CA (1) CA1106842A (fi)
CS (1) CS201512B2 (fi)
DD (2) DD139582A5 (fi)
DE (1) DE2835759A1 (fi)
DK (1) DK308878A (fi)
EG (1) EG13472A (fi)
ES (2) ES472657A1 (fi)
FI (1) FI782497A (fi)
FR (1) FR2400523A1 (fi)
GR (1) GR70241B (fi)
IE (1) IE47150B1 (fi)
IT (1) IT1098281B (fi)
LU (1) LU80124A1 (fi)
NL (1) NL7808566A (fi)
NO (1) NO782796L (fi)
PL (2) PL114720B1 (fi)
PT (1) PT68427A (fi)
SE (1) SE7808702L (fi)
SU (1) SU873889A3 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493831A (en) * 1982-10-25 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
AU2008326297B2 (en) * 2007-11-21 2012-11-08 Cipla USA, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE630462A (fi) * 1962-04-03
JPS5644076B2 (fi) * 1973-07-12 1981-10-16
US4029882A (en) * 1974-03-19 1977-06-14 Schering Corporation Selective acylation of the C-1 amino group of aminoglycoside antibiotics
US4044123A (en) * 1975-05-02 1977-08-23 Schering Corporation 6'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, methods for their use as antibacterial agents and compositions useful therefor
NZ184213A (en) * 1976-06-16 1980-05-27 Pfizer 2-deoxystreptamine aminoglycosides and antibacterial pharmaceutical compositions

Also Published As

Publication number Publication date
GR70241B (fi) 1982-09-01
NO782796L (no) 1979-02-20
ES472657A1 (es) 1979-10-16
NL7808566A (nl) 1979-02-20
AT360154B (de) 1980-12-29
BE869761A (fr) 1979-02-16
IT1098281B (it) 1985-09-07
PT68427A (en) 1978-09-01
PL209082A1 (fi) 1980-01-02
SE7808702L (sv) 1979-02-19
IT7826812A0 (it) 1978-08-17
JPS5459256A (en) 1979-05-12
IE47150B1 (en) 1983-12-28
FR2400523A1 (fr) 1979-03-16
IE781653L (en) 1979-02-18
DD148220A5 (de) 1981-05-13
DD139582A5 (de) 1980-01-09
EG13472A (en) 1981-12-31
LU80124A1 (fr) 1980-04-21
FI782497A (fi) 1979-02-19
ATA590278A (de) 1980-05-15
CA1106842A (en) 1981-08-11
AR218324A1 (es) 1980-05-30
DK308878A (da) 1979-02-19
ES479667A1 (es) 1979-08-01
PL114720B1 (en) 1981-02-28
SU873889A3 (ru) 1981-10-15
PL114954B1 (en) 1981-03-31
DE2835759A1 (de) 1979-03-08
US4178437A (en) 1979-12-11

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