LU79216A1 - Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique - Google Patents

Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique

Info

Publication number
LU79216A1
LU79216A1 LU79216A LU79216A LU79216A1 LU 79216 A1 LU79216 A1 LU 79216A1 LU 79216 A LU79216 A LU 79216A LU 79216 A LU79216 A LU 79216A LU 79216 A1 LU79216 A1 LU 79216A1
Authority
LU
Luxembourg
Prior art keywords
preparation
cephalosporanic acid
amino thiazolyl
acetamido cephalosporanic
oximes derived
Prior art date
Application number
LU79216A
Other languages
English (en)
French (fr)
Inventor
R Heymes
A Lutz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7601834A external-priority patent/FR2346014A1/fr
Priority claimed from FR7617743A external-priority patent/FR2361893A2/fr
Priority claimed from FR7625051A external-priority patent/FR2361894A2/fr
Priority claimed from FR7707307A external-priority patent/FR2383188A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of LU79216A1 publication Critical patent/LU79216A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU79216A 1976-01-23 1978-03-10 Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique LU79216A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7617743A FR2361893A2 (fr) 1976-01-23 1976-06-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7625051A FR2361894A2 (fr) 1976-01-23 1976-08-18 Nouvelles oximes derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7707307A FR2383188A2 (fr) 1976-01-23 1977-03-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
LU79216A1 true LU79216A1 (fr) 1978-11-27

Family

ID=27446319

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79216A LU79216A1 (fr) 1976-01-23 1978-03-10 Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique

Country Status (5)

Country Link
US (4) US4152432A (xx)
BE (1) BE852971R (xx)
DE (2) DE2760123C2 (xx)
GB (1) GB1580622A (xx)
LU (1) LU79216A1 (xx)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
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US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
JPS5760345B2 (xx) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SE440655B (sv) 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
US4376203A (en) * 1976-01-23 1983-03-08 Roussell Uclaf Novel 3-acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
US5336776A (en) * 1976-01-23 1994-08-09 Roussel Uclaf 3-acetoxymethyl-7-(iminoacetamideo)-cephalosporanic acid
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
US4364943A (en) * 1976-04-12 1982-12-21 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 7-[2-alkoxyimino-2-(2-amino-alkanoylamino-or haloalkanoylamino-thiazol-4-yl) acetamids]-3-[hexanoyl-, or phenylalkanoyl-oxymethyl or benzothiazolylthiomethyl]-3-cephem-4-carboxylic acid
US4304770A (en) * 1976-04-12 1981-12-08 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
US4804752A (en) * 1976-04-12 1989-02-14 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
US4493833A (en) * 1976-04-12 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds
US4331664A (en) * 1976-04-12 1982-05-25 Fujisawa Pharmaceutical Co., Ltd. Syn isomer of 7-[2-cyclo(lower) alkoxyimino-2-(2-amino-or substituted aminothiazol-4-yl)acetamido]-3-lower alkanoyloxymethyl or heterocyclicthiomethyl-3-cephem-4-carboxylic acid compounds
US4431643A (en) * 1976-04-12 1984-02-14 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3-substituted-7-[2-cyclopentyloxyimino-2-(2-aminothiazol-4-yl)-acetamido]-3
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
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JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
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DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
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FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
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FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5936891B2 (ja) * 1977-12-09 1984-09-06 武田薬品工業株式会社 保護基の脱離方法
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CN103265562A (zh) * 2013-05-29 2013-08-28 四川方向药业有限责任公司 头孢克肟的制备方法
CN113637025B (zh) * 2020-05-11 2023-02-03 承德医学院 一种头孢噻肟镁化合物、其制备方法及应用
CN114014823B (zh) * 2021-12-15 2023-07-07 山东金城医药化工有限公司 反式去甲氨噻肟酸乙酯的制备方法

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Also Published As

Publication number Publication date
DE2760123C2 (de) 1986-04-30
BE852971R (fr) 1977-09-29
US4152432A (en) 1979-05-01
GB1580622A (en) 1980-12-03
US5103012A (en) 1992-04-07
US4843164A (en) 1989-06-27
DE2714747A1 (de) 1978-11-23
US4283396A (en) 1981-08-11

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