FR2286817A1 - Procede de preparation d'acide 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indenyl-3-acetique - Google Patents

Procede de preparation d'acide 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indenyl-3-acetique

Info

Publication number
FR2286817A1
FR2286817A1 FR7529068A FR7529068A FR2286817A1 FR 2286817 A1 FR2286817 A1 FR 2286817A1 FR 7529068 A FR7529068 A FR 7529068A FR 7529068 A FR7529068 A FR 7529068A FR 2286817 A1 FR2286817 A1 FR 2286817A1
Authority
FR
France
Prior art keywords
methylsulfinylbenzylidene
indenyl
fluoro
methyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7529068A
Other languages
English (en)
Other versions
FR2286817B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2286817A1 publication Critical patent/FR2286817A1/fr
Application granted granted Critical
Publication of FR2286817B1 publication Critical patent/FR2286817B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
FR7529068A 1974-10-02 1975-09-23 Procede de preparation d'acide 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indenyl-3-acetique Granted FR2286817A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/511,349 US3998875A (en) 1974-10-02 1974-10-02 Process of preparing 5-fluoro-2-methyl-1-(paramethylsulfinylbenzylidene)-indenyl-3-acetic acid

Publications (2)

Publication Number Publication Date
FR2286817A1 true FR2286817A1 (fr) 1976-04-30
FR2286817B1 FR2286817B1 (fr) 1979-01-05

Family

ID=24034513

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7529068A Granted FR2286817A1 (fr) 1974-10-02 1975-09-23 Procede de preparation d'acide 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indenyl-3-acetique

Country Status (21)

Country Link
US (2) US3998875A (fr)
JP (1) JPS51105049A (fr)
AT (1) AT344154B (fr)
BE (1) BE834080A (fr)
CH (1) CH615158A5 (fr)
CS (2) CS183850B2 (fr)
DD (1) DD125639A5 (fr)
DE (1) DE2543870A1 (fr)
DK (1) DK416975A (fr)
ES (1) ES441404A1 (fr)
FI (1) FI61690C (fr)
FR (1) FR2286817A1 (fr)
GB (1) GB1483980A (fr)
HU (1) HU171805B (fr)
LU (1) LU73496A1 (fr)
NL (1) NL7510944A (fr)
NO (2) NO141050C (fr)
PL (2) PL103093B1 (fr)
SE (1) SE7510329L (fr)
SU (3) SU860695A1 (fr)
YU (2) YU239875A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368127A (en) * 1979-07-02 1983-01-11 Akzona Incorporated Fabric softening compounds and method
DE3266350D1 (en) * 1981-06-11 1985-10-24 Sumitomo Chemical Co Tetrahydronaphthalene derivatives and their production
IT1190371B (it) * 1985-06-19 1988-02-16 Zambon Spa Processo per la preparazione dell'acido cis-5-fluoro-2-metil-1-(4-metiltiobenziliden)-indenil-3-acetico
US6063818A (en) * 1996-06-13 2000-05-16 Cell Pathways Inc. Substituted benzylidene indenyl formamides, acetamides and propionamides
US6121321A (en) * 1996-06-13 2000-09-19 Cell Pathways, Inc. Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions
US5965619A (en) * 1996-06-13 1999-10-12 Cell Pathways Inc. Method for treating patients having precancerous lesions with substituted indene derivatives
US5998477A (en) * 1996-06-13 1999-12-07 Cell Pathways Inc. Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions
EP1219181B1 (fr) * 1996-07-01 2005-10-12 The Procter & Gamble Company Procédé pour la préparation de pommes de terre déshydratées
US5948779A (en) * 1997-12-12 1999-09-07 Cell Pathways, Inc. Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes
US6028116A (en) * 1998-04-03 2000-02-22 Cell Pathways, Inc. Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725548A (en) * 1970-05-01 1973-04-03 Merck & Co Inc Substituted indenyl acetic acids in the treatment of pain, fever or inflammation
US3766259A (en) * 1970-05-01 1973-10-16 Merck & Co Inc Preparation of 1-aryl-3-indenyl acetic acids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532752A (en) * 1965-12-30 1970-10-06 Merck & Co Inc 1-alkylidene-3-indenyl aliphatic amines
US3547923A (en) * 1968-03-25 1970-12-15 Bristol Myers Co Piperazyl ethyl 7h-benzocycloheptenes
US3654349A (en) * 1970-05-01 1972-04-04 Merck & Co Inc Substituted indenyl acetic acids
US3692825A (en) * 1970-05-01 1972-09-19 Merck & Co Inc Indanyl acetic acids
US3870753A (en) * 1973-12-20 1975-03-11 Merck & Co Inc Process for preparing indenyl acetic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725548A (en) * 1970-05-01 1973-04-03 Merck & Co Inc Substituted indenyl acetic acids in the treatment of pain, fever or inflammation
US3766259A (en) * 1970-05-01 1973-10-16 Merck & Co Inc Preparation of 1-aryl-3-indenyl acetic acids

Also Published As

Publication number Publication date
FI61690C (fi) 1982-09-10
SU957760A3 (ru) 1982-09-07
AT344154B (de) 1978-07-10
NO146198B (no) 1982-05-10
NO791267L (no) 1976-04-05
PL103093B1 (pl) 1979-05-31
HU171805B (hu) 1978-03-28
YU141481A (en) 1982-02-28
GB1483980A (en) 1977-08-24
JPS51105049A (en) 1976-09-17
FI752573A (fr) 1976-04-03
FI61690B (fi) 1982-05-31
US4123457A (en) 1978-10-31
LU73496A1 (fr) 1976-08-19
SU995705A3 (ru) 1983-02-07
CS183850B2 (en) 1978-07-31
PL103733B1 (pl) 1979-07-31
SU860695A1 (ru) 1981-08-30
FR2286817B1 (fr) 1979-01-05
ES441404A1 (es) 1977-03-01
DD125639A5 (fr) 1977-05-04
NO753179L (fr) 1976-04-05
YU239875A (en) 1982-06-30
NO141050C (no) 1980-01-02
NO146198C (no) 1982-08-18
CH615158A5 (fr) 1980-01-15
CS183821B2 (en) 1978-07-31
ATA734575A (de) 1977-11-15
NO141050B (no) 1979-09-24
US3998875A (en) 1976-12-21
SE7510329L (sv) 1976-04-05
DK416975A (da) 1976-04-03
NL7510944A (nl) 1976-04-06
DE2543870A1 (de) 1976-04-22
BE834080A (fr) 1976-04-01

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Legal Events

Date Code Title Description
ST Notification of lapse