FR2383188A2 - Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments - Google Patents

Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Info

Publication number
FR2383188A2
FR2383188A2 FR7707307A FR7707307A FR2383188A2 FR 2383188 A2 FR2383188 A2 FR 2383188A2 FR 7707307 A FR7707307 A FR 7707307A FR 7707307 A FR7707307 A FR 7707307A FR 2383188 A2 FR2383188 A2 FR 2383188A2
Authority
FR
France
Prior art keywords
oximes
thiazolyl
useful
gram positive
against gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7707307A
Other languages
English (en)
Other versions
FR2383188B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7601834A external-priority patent/FR2346014A1/fr
Priority to DE2760123A priority Critical patent/DE2760123C2/de
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7707307A priority patent/FR2383188A2/fr
Priority to CH361877A priority patent/CH619234A5/fr
Priority to BE176189A priority patent/BE852971R/fr
Priority to SE7703776A priority patent/SE7703776L/xx
Priority to IT48771/77A priority patent/IT1115958B/it
Priority to GB13839/77A priority patent/GB1580622A/en
Priority to DE19772714747 priority patent/DE2714747A1/de
Priority to NZ183767A priority patent/NZ183767A/xx
Priority to NL7703615A priority patent/NL7703615A/xx
Priority to PL1977197138A priority patent/PL124946B3/pl
Priority to IE706/77A priority patent/IE45600B1/en
Priority to EG186/77A priority patent/EG12997A/xx
Priority to YU00898/77A priority patent/YU89877A/xx
Priority to ZA00772331A priority patent/ZA772331B/xx
Priority to MX775661U priority patent/MX4959E/es
Priority to US05/817,114 priority patent/US4152432A/en
Priority to AU29622/77A priority patent/AU511864B2/en
Priority to LU79216A priority patent/LU79216A1/fr
Priority to CS781544A priority patent/CS207576B2/cs
Priority to AT263478A priority patent/AT357672B/de
Priority to US05/917,985 priority patent/US4283396A/en
Priority to US05/920,704 priority patent/US4196205A/en
Publication of FR2383188A2 publication Critical patent/FR2383188A2/fr
Application granted granted Critical
Publication of FR2383188B2 publication Critical patent/FR2383188B2/fr
Priority to SU802949072A priority patent/SU932986A3/ru
Priority to US06/449,680 priority patent/US4843164A/en
Priority to US07/582,386 priority patent/US5103012A/en
Priority to US07/777,614 priority patent/US5336776A/en
Priority to GEAP19931356A priority patent/GEP19960530B/en
Priority to MD94-0269A priority patent/MD228C2/ro
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Les produits répondant à la formule 1 du brevet principal dont les noms suivent : L'acide 7-/2 (2-amino 4-thiazolyl) 2-hydroxyimino acétamido/3-acétoxy méthyl ceph-3-ème 4-carboxylique, isomère syn et ses sels avec les métaux alcalins, alcalino-terreux, le magnésium ou les bases organiques aminées, et leur application comme médicaments, ainsi que des variantes de procédés décrits dans le brevet principal.
FR7707307A 1976-01-23 1977-03-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments Granted FR2383188A2 (fr)

Priority Applications (29)

Application Number Priority Date Filing Date Title
DE2760123A DE2760123C2 (de) 1976-01-23 1977-01-21 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
FR7707307A FR2383188A2 (fr) 1976-01-23 1977-03-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
CH361877A CH619234A5 (en) 1977-03-11 1977-03-22 Process for the preparation of new oximes derived from 7-(aminothiazolylacetamido)cephalosporanic acid
BE176189A BE852971R (fr) 1976-01-23 1977-03-29 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
SE7703776A SE7703776L (sv) 1977-03-11 1977-03-31 Sett att frastella nya oximderivat av 7-amino-tiazolylacetamidocefalosporansyra samt anvendning derav som lelemedel
IT48771/77A IT1115958B (it) 1977-03-11 1977-03-31 Procedimento per la produzione di ossime derivate dall'acido 7-amminotiazolilacetammidocefalosporanico e prodotto ottenuto
GB13839/77A GB1580622A (en) 1976-01-23 1977-04-01 Oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporanic acid processes for their preparation and pharmaceutical compositions containing them
DE19772714747 DE2714747A1 (de) 1976-01-23 1977-04-01 Neue oxime der 7-aminothiazolylacetamidocephalosporansaeure, herstellungsverfahren, pharmazeutische zusammensetzungen und anwendung als arzneimittel
NZ183767A NZ183767A (en) 1977-01-21 1977-04-01 Oxime derivatives of 7/amino-thiazolyl-acetamido-cephalosporanic acid
NL7703615A NL7703615A (nl) 1977-03-11 1977-04-01 7-amino thiazolyl cefalosporaanzuuroximen.
PL1977197138A PL124946B3 (en) 1977-03-11 1977-04-01 Process for preparing novel oxime derivatives of 7-amino-thiazolylacetamidecephalosporanic acid
IE706/77A IE45600B1 (en) 1977-01-24 1977-04-01 New oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporanic acid, processes for their preparation and pharmaceutical compositions containing them
EG186/77A EG12997A (en) 1977-03-11 1977-04-04 Nouvelles oximes derivees de l'acide 7 amino thiazolyl acetamido cephalosporanique leur procede de preparation et leur application comme medicaments
YU00898/77A YU89877A (en) 1977-03-11 1977-04-05 Process for obtaining new oxime derivatives of 7-amino-thiazolyl-acetamino-cephalosporanic acid
ZA00772331A ZA772331B (en) 1977-03-11 1977-04-18 New oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for their preparation and their application as medicaments
MX775661U MX4959E (es) 1977-03-11 1977-04-26 Procedimiento para preparar oximas derivadas del acido 7 amino tiazolil-acetamido cefalosporanico
US05/817,114 US4152432A (en) 1976-01-23 1977-07-19 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
AU29622/77A AU511864B2 (en) 1977-03-11 1977-10-12 Oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid
LU79216A LU79216A1 (fr) 1976-01-23 1978-03-10 Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
CS781544A CS207576B2 (en) 1977-03-11 1978-03-11 Method of preparation of the oxime derivatives of the 7-a-minothiazolylacetamidocephapsosporane acid
AT263478A AT357672B (de) 1977-03-11 1978-04-14 Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure
US05/917,985 US4283396A (en) 1976-01-23 1978-06-22 3-Acetoxymethyl-7-(hydroxyiminoacetamido)-cephalosporanic acid derivatives
US05/920,704 US4196205A (en) 1976-01-23 1978-06-30 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
SU802949072A SU932986A3 (ru) 1977-03-11 1980-07-21 Способ получени 7-/2-(2-аминотиазолил-4)-2-оксииминоацетамидо/-3/ацетоксиметил-3-цефем-4-карбоновой кислоты или ее солей с щелочными металлами
US06/449,680 US4843164A (en) 1976-01-23 1982-12-14 Aminothiazolyl acetic acid derivatives
US07/582,386 US5103012A (en) 1976-01-23 1990-09-13 3-acetoxymethyl-7-(iminoacetamino)-cephalosporanic acid derivatives
US07/777,614 US5336776A (en) 1976-01-23 1991-10-16 3-acetoxymethyl-7-(iminoacetamideo)-cephalosporanic acid
GEAP19931356A GEP19960530B (en) 1977-03-11 1993-07-31 Process for producing 7-(2-aminothiazolyl-4)-(2-oxyimino-acetamido)-3-acetoxymethyl-2-cefem-4-carboxylic acid or its alkali metal salts
MD94-0269A MD228C2 (ro) 1977-01-18 1994-09-08 Procedeu de obţinere a acidului 7-ő2-(2-aminotiazolil-4)-2-oximiinoacetamidoo-3-acetoximetil-3-cefem-4-carbonic sau a sărurilor lui cu metale alcaline

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7707307A FR2383188A2 (fr) 1976-01-23 1977-03-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2383188A2 true FR2383188A2 (fr) 1978-10-06
FR2383188B2 FR2383188B2 (fr) 1980-04-18

Family

ID=26219264

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7707307A Granted FR2383188A2 (fr) 1976-01-23 1977-03-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Country Status (1)

Country Link
FR (1) FR2383188A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727753A1 (de) * 1976-09-08 1978-03-16 Takeda Chemical Industries Ltd Neue cephalosporinderivate und verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727753A1 (de) * 1976-09-08 1978-03-16 Takeda Chemical Industries Ltd Neue cephalosporinderivate und verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2760448C2 (fr) * 1976-09-08 1989-06-22 Takeda Chemical Industries, Ltd., Osaka, Jp

Also Published As

Publication number Publication date
FR2383188B2 (fr) 1980-04-18

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