ES484321A1 - Un procedimiento para la preparacion de un compuesto de 3- carbamoiloximetil-cefalosporina - Google Patents

Un procedimiento para la preparacion de un compuesto de 3- carbamoiloximetil-cefalosporina

Info

Publication number
ES484321A1
ES484321A1 ES484321A ES484321A ES484321A1 ES 484321 A1 ES484321 A1 ES 484321A1 ES 484321 A ES484321 A ES 484321A ES 484321 A ES484321 A ES 484321A ES 484321 A1 ES484321 A1 ES 484321A1
Authority
ES
Spain
Prior art keywords
preparation
cephalosporin compounds
cephalosporin compound
cephalosporin
phosphonocarbamoyloxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES484321A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB7912215A external-priority patent/GB2018764B/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES484321A1 publication Critical patent/ES484321A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Un procedimiento para la preparación de un compuesto de 3-carbamoiloximetil-cefalosporina que comprende hidrolizar un compuesto de 3-fosfornocarbamoiloximetil-cefalosporina.
ES484321A 1979-04-06 1979-09-20 Un procedimiento para la preparacion de un compuesto de 3- carbamoiloximetil-cefalosporina Expired ES484321A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7912215A GB2018764B (en) 1978-04-07 1979-04-06 Cephalosporin compounds

Publications (1)

Publication Number Publication Date
ES484321A1 true ES484321A1 (es) 1980-10-01

Family

ID=10504408

Family Applications (1)

Application Number Title Priority Date Filing Date
ES484321A Expired ES484321A1 (es) 1979-04-06 1979-09-20 Un procedimiento para la preparacion de un compuesto de 3- carbamoiloximetil-cefalosporina

Country Status (17)

Country Link
US (1) US4258183A (es)
JP (1) JPS55136289A (es)
KR (1) KR830000686B1 (es)
AT (1) AT367424B (es)
BE (1) BE878900A (es)
CH (1) CH646975A5 (es)
DE (1) DE2938065A1 (es)
DK (1) DK159155C (es)
ES (1) ES484321A1 (es)
FI (1) FI73437C (es)
FR (1) FR2453176A1 (es)
IL (1) IL58287A (es)
IT (1) IT1164704B (es)
NL (1) NL7907000A (es)
PT (1) PT70205A (es)
SE (1) SE445738B (es)
YU (1) YU230379A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
IN189046B (es) 1998-03-30 2002-12-14 Ranbaxy Lab Ltd
WO2000053609A1 (en) * 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime
KR100669507B1 (ko) * 2000-08-01 2007-01-16 보령제약 주식회사 세푸록심의 제조방법
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE664955A (es) * 1964-06-05
US3905967A (en) * 1971-05-07 1975-09-16 Smithkline Corp Method for O-acylating 7-acylamino-cephalosporadesic acids
US3875152A (en) * 1971-11-09 1975-04-01 American Home Prod Intermediates for producing semi-synthetic cephalosporins and methods of production
NL7216136A (es) * 1971-12-14 1973-06-18
GB1519997A (en) * 1974-09-20 1978-08-02 Sumitomo Chemical Co Preparation o peptides and cephalosporis
JPS53135996A (en) * 1977-04-27 1978-11-28 Takeda Chem Ind Ltd Preparation of cephalosporin compounds
FI791148A (fi) * 1978-04-07 1979-10-08 Glaxo Group Ltd Foerbaettringar i eller i anslutning till kefalosporinfoereningar

Also Published As

Publication number Publication date
BE878900A (fr) 1980-03-20
IL58287A0 (en) 1979-12-30
PT70205A (en) 1979-10-01
FI73437C (fi) 1987-10-09
CH646975A5 (de) 1984-12-28
DK159155B (da) 1990-09-10
KR830000686B1 (ko) 1983-03-29
IT1164704B (it) 1987-04-15
SE7907815L (sv) 1980-10-07
FI73437B (fi) 1987-06-30
DE2938065C2 (es) 1991-03-14
DE2938065A1 (de) 1980-10-16
SE445738B (sv) 1986-07-14
US4258183A (en) 1981-03-24
ATA619879A (de) 1981-11-15
JPS55136289A (en) 1980-10-23
IL58287A (en) 1982-08-31
IT7950306A0 (it) 1979-09-20
DK392879A (da) 1980-10-07
JPS638955B2 (es) 1988-02-25
AT367424B (de) 1982-07-12
FI792928A (fi) 1980-10-07
YU230379A (en) 1983-06-30
FR2453176B1 (es) 1983-12-30
DK159155C (da) 1991-02-11
NL7907000A (nl) 1980-10-08
FR2453176A1 (fr) 1980-10-31

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506