ES485098A1 - Derivados de dibenzotiepin y un proceso para la produccion- del mismo. - Google Patents
Derivados de dibenzotiepin y un proceso para la produccion- del mismo.Info
- Publication number
- ES485098A1 ES485098A1 ES485098A ES485098A ES485098A1 ES 485098 A1 ES485098 A1 ES 485098A1 ES 485098 A ES485098 A ES 485098A ES 485098 A ES485098 A ES 485098A ES 485098 A1 ES485098 A1 ES 485098A1
- Authority
- ES
- Spain
- Prior art keywords
- producing
- same
- dibenzothiepin
- derivatives
- dibenzothiepin derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008510 dibenzothiepins Chemical class 0.000 title 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
El compuesto se produce mediante la hidrolización del compuesto. La reacción se lleva a cabo por cualquier de los métodos usuales es decir, con el uso de agua o de un disolvente que contengan una pequeña cantidad de agua, por ejemplo, un alcohol, como por ejemplo metal o etanol, en presencia de un catalizador, como por ejemplo el hidróxido de potasio, el hidróxido de sodio, el ácido clorhídrico o el acido sulfúrico, a temperaturas, que van desde la temperatura ambiente hasta el punto de ebullición del disolvente, durante un espacio de 3 a 10 horas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12684678A JPS5553282A (en) | 1978-10-17 | 1978-10-17 | Dibenzothiepin derivative and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES485098A1 true ES485098A1 (es) | 1980-09-01 |
Family
ID=14945305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES485098A Expired ES485098A1 (es) | 1978-10-17 | 1979-10-17 | Derivados de dibenzotiepin y un proceso para la produccion- del mismo. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4247706A (es) |
| JP (1) | JPS5553282A (es) |
| CA (1) | CA1127165A (es) |
| CH (1) | CH641798A5 (es) |
| DE (1) | DE2941869A1 (es) |
| ES (1) | ES485098A1 (es) |
| FR (1) | FR2439194A1 (es) |
| GB (1) | GB2035311B (es) |
| IT (1) | IT1121483B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536507A (en) * | 1977-07-26 | 1985-08-20 | Merck & Co., Inc. | Prostaglandin antagonists |
| JPS54115388A (en) * | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
| JPS57106678A (en) * | 1980-12-23 | 1982-07-02 | Nippon Chemiphar Co Ltd | Preparation of dibenzothiepinpropionic acid derivative |
| JPS57106656A (en) * | 1980-12-23 | 1982-07-02 | Nippon Chemiphar Co Ltd | Phenylthiophenylacetic acid derivative |
| JPS58113168A (ja) * | 1981-12-28 | 1983-07-05 | Fuji Photo Film Co Ltd | ５−（１−カルボキシエチル）−２−フエニルチオフエニル酢酸の製造法 |
| JPS58203986A (ja) * | 1982-05-20 | 1983-11-28 | Nippon Chemiphar Co Ltd | 光学活性ジベンゾチエピン酸を含有する薬剤 |
| US4891433A (en) * | 1986-06-10 | 1990-01-02 | Nippon Chemiphar Co., Ltd. | Process for the preparation of dibenzothiepin derivative |
| EP0309626B1 (en) * | 1987-09-30 | 1992-05-06 | Nippon Chemiphar Co., Ltd. | Process for the preparation of dibenzothiepin derivative |
| AU3952497A (en) * | 1996-08-22 | 1998-03-06 | Nippon Chemiphar Co. Ltd. | Process for preparing 2-(10,11-dihydro-10-oxodibenzo{b,f}thiepin-2-yl)propionic acid and intermediates therefor |
| IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
| KR100898099B1 (ko) | 2007-05-28 | 2009-05-15 | 주식회사 엔지켐 | 잘토프로펜의 제조방법 |
| EP2842952A4 (en) | 2012-04-24 | 2015-09-09 | Nippon Chemiphar Co | PROCESS FOR PRODUCING ZALTOPROFEN AND ITS DERIVATIVE |
| KR20200077911A (ko) | 2018-12-21 | 2020-07-01 | (주)유케이케미팜 | 잘토프로펜 함유 서방성 의약 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4101667A (en) * | 1975-05-30 | 1978-07-18 | Nippon Chemiphar Co., Ltd. | Benzo[b,f]thiepin derivatives |
| US4205170A (en) * | 1976-12-03 | 1980-05-27 | Nippon Chemiphar Company, Limited | Propionic acid derivatives |
| US4104280A (en) * | 1977-02-04 | 1978-08-01 | Syntex (U.S.A.) Inc. | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives |
| JPS54122284A (en) * | 1978-02-17 | 1979-09-21 | Dainippon Pharmaceut Co Ltd | Dibenzb,foxepin derivative |
| JPS54115388A (en) * | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
-
1978
- 1978-10-17 JP JP12684678A patent/JPS5553282A/ja active Granted
-
1979
- 1979-10-12 US US06/084,163 patent/US4247706A/en not_active Expired - Lifetime
- 1979-10-16 CA CA337,710A patent/CA1127165A/en not_active Expired
- 1979-10-16 CH CH929879A patent/CH641798A5/fr not_active IP Right Cessation
- 1979-10-16 IT IT69010/79A patent/IT1121483B/it active
- 1979-10-16 FR FR7925685A patent/FR2439194A1/fr active Granted
- 1979-10-16 DE DE19792941869 patent/DE2941869A1/de active Granted
- 1979-10-16 GB GB7935949A patent/GB2035311B/en not_active Expired
- 1979-10-17 ES ES485098A patent/ES485098A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2439194A1 (fr) | 1980-05-16 |
| GB2035311B (en) | 1982-07-14 |
| CH641798A5 (fr) | 1984-03-15 |
| GB2035311A (en) | 1980-06-18 |
| JPS5553282A (en) | 1980-04-18 |
| JPS617199B2 (es) | 1986-03-04 |
| FR2439194B1 (es) | 1984-02-03 |
| IT7969010A0 (it) | 1979-10-16 |
| CA1127165A (en) | 1982-07-06 |
| US4247706A (en) | 1981-01-27 |
| DE2941869A1 (de) | 1980-04-30 |
| DE2941869C2 (es) | 1988-07-21 |
| IT1121483B (it) | 1986-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010301 |