ES8105982A1 - Procedimiento de preparacion del carbanion de la papaverina - Google Patents

Procedimiento de preparacion del carbanion de la papaverina

Info

Publication number
ES8105982A1
ES8105982A1 ES493502A ES493502A ES8105982A1 ES 8105982 A1 ES8105982 A1 ES 8105982A1 ES 493502 A ES493502 A ES 493502A ES 493502 A ES493502 A ES 493502A ES 8105982 A1 ES8105982 A1 ES 8105982A1
Authority
ES
Spain
Prior art keywords
carbanion
papavrine
forming
solution
papaverine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493502A
Other languages
English (en)
Other versions
ES493502A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES493502A0 publication Critical patent/ES493502A0/es
Publication of ES8105982A1 publication Critical patent/ES8105982A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DEL CARBANION DE LA PAPAVERINA DE FORMULA (I). CONSISTE EN HACER REACCIONAR CON LA PAPAVERINA, DISUELTA EN UN DISOLVENTE BASICO, UN AGENTE MUY BASICO EN EXCESO. COMO DISOLVENTES PUEDEN EMPLEARSE HEXAMETIL-FOSFOTRIAMIDA, TETRAHIDROFURANO, DIMETIL FORMAMIDA O AMONIACO LIQUIDO. COMO AGENTES MUY BASICOS PUEDEN UTILIZARSE BUTIL-LITIO, UN ALCOHIL-AMIDURO DE LITIO, AMIDURO DE SODIO O AMIDURO DE POTASIO. EXISTEN DIFERENTES ALTERNATIVAS PARA OBTENER EL CARBANION, VARIANDO EL PAR AGENTE MUY BASICO-DISOLVENTE BASICO. DE APLICACION EN LA SINTESIS DE OTROS COMPUESTOS. *FORMULA*
ES493502A 1979-07-19 1980-07-18 Procedimiento de preparacion del carbanion de la papaverina Expired ES8105982A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7925275 1979-07-19

Publications (2)

Publication Number Publication Date
ES493502A0 ES493502A0 (es) 1981-07-01
ES8105982A1 true ES8105982A1 (es) 1981-07-01

Family

ID=10506636

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493502A Expired ES8105982A1 (es) 1979-07-19 1980-07-18 Procedimiento de preparacion del carbanion de la papaverina

Country Status (30)

Country Link
US (1) US4501891A (es)
JP (1) JPS5618965A (es)
AU (1) AU538064B2 (es)
BE (1) BE884241A (es)
CA (1) CA1152997A (es)
CH (1) CH645627A5 (es)
DE (1) DE3027325A1 (es)
DK (1) DK310080A (es)
EG (1) EG14652A (es)
ES (1) ES8105982A1 (es)
FI (1) FI802117A (es)
FR (1) FR2461701A1 (es)
GB (1) GB2058754B (es)
GR (1) GR69196B (es)
IE (1) IE50069B1 (es)
IL (1) IL60481A (es)
IN (1) IN154317B (es)
IT (1) IT1237318B (es)
LU (1) LU82591A1 (es)
MA (1) MA18908A1 (es)
MX (1) MX5827E (es)
MY (1) MY8400340A (es)
NL (1) NL8003957A (es)
NO (1) NO158801C (es)
NZ (1) NZ194279A (es)
OA (1) OA06611A (es)
PT (1) PT71577A (es)
SE (1) SE459091B (es)
SG (1) SG48683G (es)
ZA (1) ZA803992B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA803993B (en) * 1979-07-19 1981-07-29 Buzas Andre New isoquinoline derivatives and preparation thereof
US4559403A (en) * 1983-05-19 1985-12-17 Hoffmann-La Roche Inc. Substituted isoquinolines
US4544657A (en) * 1983-05-19 1985-10-01 Hoffmann-La Roche Inc. Substituted isoquinolines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1176597A (en) * 1914-07-28 1916-03-21 Chem Ind Basel Condensation products of the papaverine series and a process of making same.
US3966724A (en) * 1974-12-20 1976-06-29 Armour Pharmaceutical Company 1-(α-Aminomethylbenzyl)isoquinoline compounds

Also Published As

Publication number Publication date
GB2058754B (en) 1983-05-25
LU82591A1 (fr) 1980-10-08
ES493502A0 (es) 1981-07-01
GR69196B (es) 1982-05-06
IT8023535A0 (it) 1980-07-18
DK310080A (da) 1981-01-20
IL60481A (en) 1985-04-30
IT1237318B (it) 1993-05-31
MX5827E (es) 1984-07-30
GB2058754A (en) 1981-04-15
MY8400340A (en) 1984-12-31
AU6062980A (en) 1981-01-22
CH645627A5 (fr) 1984-10-15
IN154317B (es) 1984-10-13
IE50069B1 (en) 1986-02-05
US4501891A (en) 1985-02-26
DE3027325A1 (de) 1981-02-12
NO158801C (no) 1988-11-02
NO802159L (no) 1981-01-20
JPS5618965A (en) 1981-02-23
IL60481A0 (en) 1980-09-16
AU538064B2 (en) 1984-07-26
SG48683G (en) 1984-07-27
OA06611A (fr) 1981-08-31
SE459091B (sv) 1989-06-05
MA18908A1 (fr) 1981-04-01
FR2461701B1 (es) 1982-11-19
NO158801B (no) 1988-07-25
BE884241A (fr) 1980-11-03
NZ194279A (en) 1982-11-23
SE8005259L (sv) 1981-01-20
ZA803992B (en) 1981-06-24
IE801499L (en) 1981-01-19
PT71577A (en) 1980-08-01
FR2461701A1 (fr) 1981-02-06
EG14652A (en) 1985-03-31
FI802117A (fi) 1981-01-20
NL8003957A (nl) 1981-01-21
CA1152997A (en) 1983-08-30

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