ES8304138A1 - Un procedimiento para la produccion de amoxicilina sodica solida. - Google Patents

Un procedimiento para la produccion de amoxicilina sodica solida.

Info

Publication number
ES8304138A1
ES8304138A1 ES511295A ES511295A ES8304138A1 ES 8304138 A1 ES8304138 A1 ES 8304138A1 ES 511295 A ES511295 A ES 511295A ES 511295 A ES511295 A ES 511295A ES 8304138 A1 ES8304138 A1 ES 8304138A1
Authority
ES
Spain
Prior art keywords
drying
production
spray
sodium amoxicillin
amoxicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511295A
Other languages
English (en)
Other versions
ES511295A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8304138A1 publication Critical patent/ES8304138A1/es
Publication of ES511295A0 publication Critical patent/ES511295A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/14—Preparation of salts
    • C07D499/16—Preparation of salts of alkali or alkaline earth metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PRODUCCION DE AMOXICILINA SODICA SOLIDA. CONSISTE EN SECAR POR ATOMIZACION UNA SOLUCION DE AMOXICILINA SODICA EN T-BUTANOL ACUOSO. LA TEMPERATURA DE ENTRADA ES DE UNOS 180 C MIENTRAS QUE LA DE SALIDA ES DE 120 C. LA SOLUCION QUE SE SECA CONTIENE APROXIMADAMENTE 1,5 LITROS DE T-BUTANOL POR CADA 3,6 LITROS DE AGUA. SE EMPLEA UN DESECADOR DE ROCIO DE CICLO CERRADO CUYOS COMPONENTES PRINCIPALES SON UNA CAMARA DESECADORA, UNA CENTRIFUGA DE PRODUCTOS, UN VENTILADOR EDUCTOR, UN CONDENSADOR/DEPURADOR, UN VENTILADOR DE NITROGENO, UN INTERCAMBIADOR DE CALOR Y UNA BOMBA DE ALIMENTACION. EL APARATO SE MONTA PARA LA OPERACION SIMULTANEA CON DESCARGA DEL PRODUCTO DE LA CENTRIFU
ES511295A 1981-04-10 1982-04-07 Un procedimiento para la produccion de amoxicilina sodica solida. Granted ES511295A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8107247A FR2503710B1 (fr) 1981-04-10 1981-04-10 Procede de production du sel de sodium de l'amoxicilline

Publications (2)

Publication Number Publication Date
ES8304138A1 true ES8304138A1 (es) 1983-02-16
ES511295A0 ES511295A0 (es) 1983-02-16

Family

ID=9257255

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511295A Granted ES511295A0 (es) 1981-04-10 1982-04-07 Un procedimiento para la produccion de amoxicilina sodica solida.

Country Status (23)

Country Link
JP (1) JPS57179191A (es)
KR (1) KR880001410B1 (es)
AU (1) AU559766B2 (es)
BE (1) BE892451A (es)
CA (1) CA1182108A (es)
CH (1) CH651836A5 (es)
DE (1) DE3213308A1 (es)
DK (1) DK157382A (es)
ES (1) ES511295A0 (es)
FI (1) FI821247L (es)
FR (1) FR2503710B1 (es)
GB (1) GB2096599B (es)
GR (1) GR76106B (es)
IE (1) IE52939B1 (es)
IT (1) IT1148165B (es)
LU (1) LU84007A1 (es)
NL (1) NL8201467A (es)
NO (1) NO821174L (es)
NZ (1) NZ200281A (es)
PT (1) PT74727B (es)
SE (1) SE8202269L (es)
YU (1) YU43132B (es)
ZA (1) ZA822400B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131147B2 (en) * 1983-06-10 1996-12-04 Beecham Group p.l.c. Crystalline amoxycillin salt
IT1255716B (it) * 1992-10-05 1995-11-10 Procedimento per la preparazione di antibiotici beta-lattamici sterili
AT412213B (de) 2000-05-30 2004-11-25 Sandoz Ag Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
CN105055169B (zh) * 2015-07-11 2019-01-22 鲁南制药集团股份有限公司 一种制备亚胺培南西司他丁钠无菌粉末的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1471235A (en) * 1974-09-18 1977-04-21 Beecham Group Ltd Amoxycillin derivatives
GB1527557A (en) * 1976-07-07 1978-10-04 Beecham Group Ltd Process for preparing solid sodium amoxycillin
GB1576731A (en) * 1976-08-10 1980-10-15 Beecham Group Ltd Process for the preparation of sodium amoxycillin
EP0012496B1 (en) * 1978-12-08 1983-07-20 Beecham Group Plc A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof

Also Published As

Publication number Publication date
ZA822400B (en) 1983-02-23
AU8045582A (en) 1982-10-14
KR830010116A (ko) 1983-12-26
CH651836A5 (fr) 1985-10-15
BE892451A (fr) 1982-09-10
DE3213308A1 (de) 1982-11-11
IE52939B1 (en) 1988-04-13
JPS57179191A (en) 1982-11-04
FR2503710B1 (fr) 1985-07-05
CA1182108A (en) 1985-02-05
IE820844L (en) 1983-10-10
AU559766B2 (en) 1987-03-19
ES511295A0 (es) 1983-02-16
FR2503710A1 (fr) 1982-10-15
YU43132B (en) 1989-04-30
GB2096599A (en) 1982-10-20
GR76106B (es) 1984-08-03
PT74727A (en) 1982-05-01
PT74727B (en) 1985-01-08
IT8248188A0 (it) 1982-04-07
DK157382A (da) 1982-10-11
LU84007A1 (fr) 1983-02-22
NL8201467A (nl) 1982-11-01
FI821247A0 (fi) 1982-04-07
GB2096599B (en) 1985-01-23
FI821247L (fi) 1982-10-11
NO821174L (no) 1982-10-11
JPH0219119B2 (es) 1990-04-27
NZ200281A (en) 1984-12-14
SE8202269L (sv) 1982-10-11
YU43282A (en) 1985-06-30
KR880001410B1 (ko) 1988-08-01
IT1148165B (it) 1986-11-26

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