LT4072B - Use of a cross-linked polycarboxylic polymer and progesterone for manufacture of medicinal preparations - Google Patents

Use of a cross-linked polycarboxylic polymer and progesterone for manufacture of medicinal preparations Download PDF

Info

Publication number
LT4072B
LT4072B LT96-027A LT96027A LT4072B LT 4072 B LT4072 B LT 4072B LT 96027 A LT96027 A LT 96027A LT 4072 B LT4072 B LT 4072B
Authority
LT
Lithuania
Prior art keywords
progesterone
use according
polymer
medicament
levels
Prior art date
Application number
LT96-027A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT96027A (en
Inventor
William Joseph Bologna
Howard Leslie Levine
Original Assignee
Columbia Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402302&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT4072(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Inc filed Critical Columbia Lab Inc
Publication of LT96027A publication Critical patent/LT96027A/xx
Publication of LT4072B publication Critical patent/LT4072B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LT96-027A 1993-09-15 1996-03-11 Use of a cross-linked polycarboxylic polymer and progesterone for manufacture of medicinal preparations LT4072B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/122,371 US5543150A (en) 1993-09-15 1993-09-15 Method of progesterone delivery and affect thereof

Publications (2)

Publication Number Publication Date
LT96027A LT96027A (en) 1996-07-25
LT4072B true LT4072B (en) 1996-11-25

Family

ID=22402302

Family Applications (1)

Application Number Title Priority Date Filing Date
LT96-027A LT4072B (en) 1993-09-15 1996-03-11 Use of a cross-linked polycarboxylic polymer and progesterone for manufacture of medicinal preparations

Country Status (27)

Country Link
US (1) US5543150A (de)
EP (1) EP0719146B1 (de)
JP (1) JP3143474B2 (de)
KR (1) KR100278553B1 (de)
AT (1) ATE174796T1 (de)
BR (1) BR9407475A (de)
CA (1) CA2171939C (de)
CO (1) CO4290332A1 (de)
DE (1) DE69415543T2 (de)
DK (1) DK0719146T3 (de)
ES (1) ES2126783T3 (de)
FI (1) FI115444B (de)
GR (1) GR3029314T3 (de)
HU (1) HU221583B (de)
IL (1) IL110972A (de)
LT (1) LT4072B (de)
LV (1) LV11527B (de)
MA (1) MA23329A1 (de)
MY (1) MY111484A (de)
NO (1) NO308585B1 (de)
NZ (1) NZ273816A (de)
PE (1) PE50795A1 (de)
PH (1) PH30813A (de)
RU (1) RU2148393C1 (de)
UA (1) UA37244C2 (de)
WO (1) WO1995007699A1 (de)
ZA (1) ZA947073B (de)

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US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
CA2316296A1 (en) * 1997-10-10 1999-04-22 Imperial College Of Science, Technology And Medicine Use of csaidtm compounds for the management of uterine contractions
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US20070178139A1 (en) * 1998-11-18 2007-08-02 Yankov Vladimir I Vaginally administratable progesterone-containing tablets and method for preparing same
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
US6544553B1 (en) 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
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US7544348B2 (en) * 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
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US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US7572780B2 (en) 2003-01-21 2009-08-11 Dimera, Incorporated Method and kit for reducing the symptoms of peripheral vascular disease
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ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
CN1845723B (zh) * 2003-09-03 2010-07-21 迷斯康贸易有限公司 子宫内膜异位症的治疗方法
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EP1898880A2 (de) * 2005-06-16 2008-03-19 Warner Chilcott Company Inc. Gelzusammensetzungen zur topischen verabreichung
WO2006138686A1 (en) * 2005-06-16 2006-12-28 Warner Chilcott Company, Inc. Estrogen compositions for vaginal administration
WO2007143607A2 (en) * 2006-06-02 2007-12-13 Pear Tree Women's Health Care Method of treating atrophic vaginitis
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
ES2310968B1 (es) 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
JP2010539245A (ja) * 2007-09-14 2010-12-16 日東電工株式会社 薬物担体
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
GB0723882D0 (en) * 2007-12-07 2008-01-23 Univ Leicester Methods for the detection of a threatened miscarriage
DK2249757T3 (en) * 2008-02-04 2017-10-16 Ferring Bv Monolithic vaginal rings comprising progesterone and methods of preparation and use thereof.
US9107696B2 (en) * 2008-08-06 2015-08-18 Emory University Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
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EP2550288A1 (de) * 2010-03-22 2013-01-30 Repros Therapeutics Inc. Zusammensetzungen und verfahren zur nichttoxischen freisetzung von antiprogestinen
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8435972B2 (en) 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
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US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2013112947A1 (en) * 2012-01-26 2013-08-01 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
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US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
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US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103239389A (zh) * 2013-06-03 2013-08-14 南京泽恒医药技术开发有限公司 一种治疗先兆性流产的黄体酮缓释凝胶的制备方法
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
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IL310755A (en) * 2017-06-22 2024-04-01 Viramal Ltd An emulsion preparation that includes danzol for use in the treatment of endometrial conditions
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Also Published As

Publication number Publication date
KR100278553B1 (ko) 2001-01-15
DE69415543T2 (de) 1999-06-17
HU9600669D0 (en) 1996-05-28
RU2148393C1 (ru) 2000-05-10
ES2126783T3 (es) 1999-04-01
LT96027A (en) 1996-07-25
IL110972A (en) 1998-03-10
WO1995007699A1 (en) 1995-03-23
UA37244C2 (uk) 2001-05-15
LV11527B (en) 1997-02-20
NO961044L (no) 1996-05-14
BR9407475A (pt) 1996-11-12
JP3143474B2 (ja) 2001-03-07
DK0719146T3 (da) 1999-08-23
HU221583B (hu) 2002-11-28
CO4290332A1 (es) 1996-04-17
JPH09502724A (ja) 1997-03-18
CA2171939C (en) 2002-01-01
AU7726194A (en) 1995-04-03
MA23329A1 (fr) 1995-04-01
CA2171939A1 (en) 1995-03-23
PE50795A1 (es) 1996-01-19
EP0719146B1 (de) 1998-12-23
HUT76824A (en) 1997-11-28
AU689133B2 (en) 1998-03-26
NO308585B1 (no) 2000-10-02
DE69415543D1 (de) 1999-02-04
NO961044D0 (no) 1996-03-14
MY111484A (en) 2000-06-30
EP0719146A1 (de) 1996-07-03
ATE174796T1 (de) 1999-01-15
GR3029314T3 (en) 1999-05-28
LV11527A (lv) 1996-10-20
PH30813A (en) 1997-10-17
IL110972A0 (en) 1994-11-28
US5543150A (en) 1996-08-06
FI961221A0 (fi) 1996-03-15
ZA947073B (en) 1995-05-02
FI115444B (fi) 2005-05-13
FI961221A (fi) 1996-05-14
NZ273816A (en) 2007-09-28

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