ZA947073B - Novel method of progesterone delivery and affect thereof - Google Patents

Novel method of progesterone delivery and affect thereof

Info

Publication number
ZA947073B
ZA947073B ZA947073A ZA947073A ZA947073B ZA 947073 B ZA947073 B ZA 947073B ZA 947073 A ZA947073 A ZA 947073A ZA 947073 A ZA947073 A ZA 947073A ZA 947073 B ZA947073 B ZA 947073B
Authority
ZA
South Africa
Prior art keywords
progesterone
serum
affect
low levels
novel method
Prior art date
Application number
ZA947073A
Other languages
English (en)
Inventor
William J Bologna
Howard L Levine
Original Assignee
Columbia Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402302&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA947073(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Inc filed Critical Columbia Lab Inc
Publication of ZA947073B publication Critical patent/ZA947073B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA947073A 1993-09-15 1994-09-14 Novel method of progesterone delivery and affect thereof ZA947073B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/122,371 US5543150A (en) 1993-09-15 1993-09-15 Method of progesterone delivery and affect thereof

Publications (1)

Publication Number Publication Date
ZA947073B true ZA947073B (en) 1995-05-02

Family

ID=22402302

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA947073A ZA947073B (en) 1993-09-15 1994-09-14 Novel method of progesterone delivery and affect thereof

Country Status (27)

Country Link
US (1) US5543150A (de)
EP (1) EP0719146B1 (de)
JP (1) JP3143474B2 (de)
KR (1) KR100278553B1 (de)
AT (1) ATE174796T1 (de)
BR (1) BR9407475A (de)
CA (1) CA2171939C (de)
CO (1) CO4290332A1 (de)
DE (1) DE69415543T2 (de)
DK (1) DK0719146T3 (de)
ES (1) ES2126783T3 (de)
FI (1) FI115444B (de)
GR (1) GR3029314T3 (de)
HU (1) HU221583B (de)
IL (1) IL110972A (de)
LT (1) LT4072B (de)
LV (1) LV11527B (de)
MA (1) MA23329A1 (de)
MY (1) MY111484A (de)
NO (1) NO308585B1 (de)
NZ (1) NZ273816A (de)
PE (1) PE50795A1 (de)
PH (1) PH30813A (de)
RU (1) RU2148393C1 (de)
UA (1) UA37244C2 (de)
WO (1) WO1995007699A1 (de)
ZA (1) ZA947073B (de)

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DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
CA2316296A1 (en) * 1997-10-10 1999-04-22 Imperial College Of Science, Technology And Medicine Use of csaidtm compounds for the management of uterine contractions
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WO2006138686A1 (en) * 2005-06-16 2006-12-28 Warner Chilcott Company, Inc. Estrogen compositions for vaginal administration
WO2007143607A2 (en) * 2006-06-02 2007-12-13 Pear Tree Women's Health Care Method of treating atrophic vaginitis
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
ES2310968B1 (es) 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
JP2010539245A (ja) * 2007-09-14 2010-12-16 日東電工株式会社 薬物担体
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
GB0723882D0 (en) * 2007-12-07 2008-01-23 Univ Leicester Methods for the detection of a threatened miscarriage
DK2249757T3 (en) * 2008-02-04 2017-10-16 Ferring Bv Monolithic vaginal rings comprising progesterone and methods of preparation and use thereof.
US9107696B2 (en) * 2008-08-06 2015-08-18 Emory University Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
US8421747B2 (en) 2008-09-24 2013-04-16 Microsoft Corporation Object detection and user settings
ES2344675B1 (es) 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
EP2550288A1 (de) * 2010-03-22 2013-01-30 Repros Therapeutics Inc. Zusammensetzungen und verfahren zur nichttoxischen freisetzung von antiprogestinen
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8435972B2 (en) 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
WO2013010915A1 (en) * 2011-07-15 2013-01-24 Universiteit Gent Intravaginal delivery system
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
LT2782584T (lt) 2011-11-23 2021-09-10 Therapeuticsmd, Inc. Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2013112947A1 (en) * 2012-01-26 2013-08-01 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
BR112014029131B1 (pt) 2012-05-31 2021-03-09 Allergan Pharmaceuticals International Limited cápsula de mucoadesivo
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
CA2888377C (en) 2012-11-02 2021-02-02 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103239389A (zh) * 2013-06-03 2013-08-14 南京泽恒医药技术开发有限公司 一种治疗先兆性流产的黄体酮缓释凝胶的制备方法
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
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IL310755A (en) * 2017-06-22 2024-04-01 Viramal Ltd An emulsion preparation that includes danzol for use in the treatment of endometrial conditions
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Also Published As

Publication number Publication date
KR100278553B1 (ko) 2001-01-15
DE69415543T2 (de) 1999-06-17
HU9600669D0 (en) 1996-05-28
RU2148393C1 (ru) 2000-05-10
ES2126783T3 (es) 1999-04-01
LT96027A (en) 1996-07-25
IL110972A (en) 1998-03-10
WO1995007699A1 (en) 1995-03-23
UA37244C2 (uk) 2001-05-15
LV11527B (en) 1997-02-20
NO961044L (no) 1996-05-14
BR9407475A (pt) 1996-11-12
JP3143474B2 (ja) 2001-03-07
DK0719146T3 (da) 1999-08-23
HU221583B (hu) 2002-11-28
CO4290332A1 (es) 1996-04-17
JPH09502724A (ja) 1997-03-18
CA2171939C (en) 2002-01-01
AU7726194A (en) 1995-04-03
MA23329A1 (fr) 1995-04-01
CA2171939A1 (en) 1995-03-23
PE50795A1 (es) 1996-01-19
EP0719146B1 (de) 1998-12-23
HUT76824A (en) 1997-11-28
AU689133B2 (en) 1998-03-26
NO308585B1 (no) 2000-10-02
DE69415543D1 (de) 1999-02-04
NO961044D0 (no) 1996-03-14
MY111484A (en) 2000-06-30
EP0719146A1 (de) 1996-07-03
LT4072B (en) 1996-11-25
ATE174796T1 (de) 1999-01-15
GR3029314T3 (en) 1999-05-28
LV11527A (lv) 1996-10-20
PH30813A (en) 1997-10-17
IL110972A0 (en) 1994-11-28
US5543150A (en) 1996-08-06
FI961221A0 (fi) 1996-03-15
FI115444B (fi) 2005-05-13
FI961221A (fi) 1996-05-14
NZ273816A (en) 2007-09-28

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