LT3230298T - 3-padėtyje pakeisti 5-amino-6h-tiazol[4,5-d]pirimidin-2,7-diono junginiai, skirti viruso sukeliamos infekcijos gydymui ir profilaktikai - Google Patents
3-padėtyje pakeisti 5-amino-6h-tiazol[4,5-d]pirimidin-2,7-diono junginiai, skirti viruso sukeliamos infekcijos gydymui ir profilaktikaiInfo
- Publication number
- LT3230298T LT3230298T LTEP15804128.5T LT15804128T LT3230298T LT 3230298 T LT3230298 T LT 3230298T LT 15804128 T LT15804128 T LT 15804128T LT 3230298 T LT3230298 T LT 3230298T
- Authority
- LT
- Lithuania
- Prior art keywords
- thiazolo
- prophylaxis
- pyrimidine
- amino
- substituted
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2014093224 | 2014-12-08 | ||
| CN2015086987 | 2015-08-14 | ||
| PCT/EP2015/078439 WO2016091698A1 (en) | 2014-12-08 | 2015-12-03 | 3-substituted 5-amino-6h-thiazolo[4,5-d]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3230298T true LT3230298T (lt) | 2021-04-12 |
Family
ID=54771116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP15804128.5T LT3230298T (lt) | 2014-12-08 | 2015-12-03 | 3-padėtyje pakeisti 5-amino-6h-tiazol[4,5-d]pirimidin-2,7-diono junginiai, skirti viruso sukeliamos infekcijos gydymui ir profilaktikai |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US9441008B2 (lt) |
| EP (1) | EP3230298B1 (lt) |
| JP (1) | JP6817217B2 (lt) |
| KR (2) | KR20230113824A (lt) |
| CN (2) | CN106164079B (lt) |
| AU (1) | AU2015359692B2 (lt) |
| BR (1) | BR112017011941B1 (lt) |
| CA (1) | CA2963717C (lt) |
| CL (1) | CL2017001426A1 (lt) |
| CR (1) | CR20170237A (lt) |
| DK (1) | DK3230298T3 (lt) |
| EA (1) | EA038744B1 (lt) |
| ES (1) | ES2864223T3 (lt) |
| HK (1) | HK1245764A1 (lt) |
| HR (1) | HRP20210454T1 (lt) |
| HU (1) | HUE053704T2 (lt) |
| IL (1) | IL251285B (lt) |
| LT (1) | LT3230298T (lt) |
| MA (1) | MA41134B1 (lt) |
| MX (1) | MX2017007044A (lt) |
| MY (1) | MY194002A (lt) |
| PE (1) | PE20170679A1 (lt) |
| PH (1) | PH12017501061A1 (lt) |
| PL (1) | PL3230298T3 (lt) |
| PT (1) | PT3230298T (lt) |
| RS (1) | RS61612B1 (lt) |
| SG (1) | SG11201704512PA (lt) |
| SI (1) | SI3230298T1 (lt) |
| TW (1) | TWI733656B (lt) |
| UA (1) | UA124184C2 (lt) |
| WO (1) | WO2016091698A1 (lt) |
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| UA124184C2 (uk) * | 2014-12-08 | 2021-08-04 | Ф. Хоффманн-Ля Рош Аг | 3-ЗАМІЩЕНІ 5-АМІНО-6H-ТІАЗОЛО[4,5-d]ПІРИМІДИН-2,7-ДІОНОВІ СПОЛУКИ ДЛЯ ЛІКУВАННЯ І ПРОФІЛАКТИКИ ВІРУСНИХ ІНФЕКЦІЙ |
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| JP6839104B2 (ja) * | 2015-06-30 | 2021-03-03 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ウイルス感染の治療及び予防のための新規な置換アミノチアゾロピリミジンジオン |
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| EP3568400A1 (en) * | 2017-01-06 | 2019-11-20 | H. Hoffnabb-La Roche Ag | PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-d]PYRIMIDINE-2-7-DIONE COMPOUNDS |
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| BRPI0717741A2 (pt) | 2006-10-17 | 2014-04-08 | Anadys Pharmaceuticals Inc | Compostos e respectivos método de preparação, método de redução de composto de sulfonil substituído, composição farmacêutica método de tratamento ou prevenção de doença |
| US20110166092A1 (en) * | 2007-08-20 | 2011-07-07 | Anadys Pharmaceuticals, Inc. | Dosing methods for treating disease |
| UA124184C2 (uk) * | 2014-12-08 | 2021-08-04 | Ф. Хоффманн-Ля Рош Аг | 3-ЗАМІЩЕНІ 5-АМІНО-6H-ТІАЗОЛО[4,5-d]ПІРИМІДИН-2,7-ДІОНОВІ СПОЛУКИ ДЛЯ ЛІКУВАННЯ І ПРОФІЛАКТИКИ ВІРУСНИХ ІНФЕКЦІЙ |
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| JP6839104B2 (ja) | 2015-06-30 | 2021-03-03 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ウイルス感染の治療及び予防のための新規な置換アミノチアゾロピリミジンジオン |
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