KR960015399B1 - 면역 글로불린의 정제방법 - Google Patents

면역 글로불린의 정제방법 Download PDF

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Publication number
KR960015399B1
KR960015399B1 KR1019920701427A KR920701427A KR960015399B1 KR 960015399 B1 KR960015399 B1 KR 960015399B1 KR 1019920701427 A KR1019920701427 A KR 1019920701427A KR 920701427 A KR920701427 A KR 920701427A KR 960015399 B1 KR960015399 B1 KR 960015399B1
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KR
South Korea
Prior art keywords
antibody
column
protein
compass
cells
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1019920701427A
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English (en)
Korean (ko)
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KR920703108A (ko
Inventor
얀 니콜라스 라마지 폴
알렌 제프리
Original Assignee
더 웰컴 파운데이션 리미티드
엘. 디. 젠킨스
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10683866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR960015399(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 더 웰컴 파운데이션 리미티드, 엘. 디. 젠킨스 filed Critical 더 웰컴 파운데이션 리미티드
Publication of KR920703108A publication Critical patent/KR920703108A/ko
Application granted granted Critical
Publication of KR960015399B1 publication Critical patent/KR960015399B1/ko
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Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2893—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019920701427A 1990-10-17 1991-10-17 면역 글로불린의 정제방법 Expired - Lifetime KR960015399B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9022547.5 1990-10-17
GB909022547A GB9022547D0 (en) 1990-10-17 1990-10-17 Purified immunoglobulin
PCT/GB1991/001816 WO1992007084A1 (en) 1990-10-17 1991-10-17 Purified cdw52-specific antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019920702699A Division KR100193314B1 (ko) 1990-10-17 1992-10-30 정제된 면역 글로불린

Publications (2)

Publication Number Publication Date
KR920703108A KR920703108A (ko) 1992-12-17
KR960015399B1 true KR960015399B1 (ko) 1996-11-13

Family

ID=10683866

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019920701427A Expired - Lifetime KR960015399B1 (ko) 1990-10-17 1991-10-17 면역 글로불린의 정제방법
KR1019920702699A Expired - Lifetime KR100193314B1 (ko) 1990-10-17 1992-10-30 정제된 면역 글로불린

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019920702699A Expired - Lifetime KR100193314B1 (ko) 1990-10-17 1992-10-30 정제된 면역 글로불린

Country Status (29)

Country Link
US (1) US5644036A (https=)
EP (1) EP0504363B2 (https=)
JP (1) JP2638680B2 (https=)
KR (2) KR960015399B1 (https=)
AT (2) ATA900791A (https=)
AU (3) AU658926B2 (https=)
BE (1) BE1004226A5 (https=)
BR (1) BR1100358A (https=)
CA (1) CA2069481C (https=)
CH (2) CH681455A5 (https=)
DE (1) DE69128774T3 (https=)
DK (1) DK0504363T4 (https=)
ES (2) ES2112865T5 (https=)
FI (2) FI110003B (https=)
FR (2) FR2668164A1 (https=)
GB (2) GB9022547D0 (https=)
GR (3) GR910100425A (https=)
HU (1) HUT64601A (https=)
IE (1) IE913560A1 (https=)
IL (3) IL99761A0 (https=)
IT (1) IT1250064B (https=)
LU (1) LU88122A1 (https=)
MX (1) MX9203794A (https=)
MY (2) MY136210A (https=)
NZ (2) NZ240247A (https=)
PT (2) PT99248B (https=)
TW (1) TW283710B (https=)
WO (1) WO1992007084A1 (https=)
ZA (2) ZA918259B (https=)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
KR100264218B1 (ko) * 1991-10-15 2000-08-16 그레이엄 브레레톤 관절의 T-세포 매개 염증의 치료용 CDw52-특이 항체
GB9125768D0 (en) * 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
GB9300501D0 (en) * 1993-01-09 1993-03-03 Wellcome Found Purification of immunoglobulin
EP0841942B2 (fr) † 1995-08-01 2007-12-12 Sanofi Pasteur Procede de production industrielle d'un vaccin contre l'encephalite japonaise et vaccin obtenu
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
DK0929578T3 (da) * 1996-02-09 2003-08-25 Abbott Lab Bermuda Ltd Humane antistoffer, der binder human TNFalfa
GB9603256D0 (en) * 1996-02-16 1996-04-17 Wellcome Found Antibodies
US20030023043A1 (en) * 2000-03-02 2003-01-30 Kazuhisa Uchida Method of separating and purifying protein
EP3088412B1 (en) 2001-03-09 2021-05-05 Chugai Seiyaku Kabushiki Kaisha Protein purification method
DE60213248T2 (de) * 2001-06-05 2006-11-30 Genetics Institute, LLC, Cambridge Verfahren zur reinigung hochanionischer proteine
GB0220894D0 (en) * 2002-09-09 2002-10-16 Millipore Uk Ltd Method of separation
ES2558303T3 (es) 2002-09-11 2016-02-03 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
WO2004035618A2 (en) 2002-10-15 2004-04-29 Intercell Ag Nucleic acids coding for adhesion factor of group b streptococcus, adhesion factors of group b streptococcus and further uses thereof
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
JP2007515492A (ja) * 2003-12-22 2007-06-14 ジェンザイム コーポレイション 糖尿病の抗ｃｄ５２抗体治療法
AU2006223180B2 (en) * 2005-03-11 2011-11-24 Wyeth Llc A method of weak partitioning chromatography
ES2892925T3 (es) 2006-03-31 2022-02-07 Chugai Pharmaceutical Co Ltd Métodos para controlar la farmacocinética en sangre de anticuerpos
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
KR102057826B1 (ko) 2008-04-11 2019-12-20 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
CA2761885A1 (en) 2009-05-13 2010-11-18 Genzyme Corporation Methods and compositions for treating lupus
EP2998405B1 (en) 2009-05-13 2019-12-11 Genzyme Corporation Anti-human cd52 immunoglobulins
US20130178608A1 (en) * 2009-12-29 2013-07-11 Samir Kulkarni Protein purification by ion exchange
EP3266793A1 (en) 2010-06-21 2018-01-10 Kyowa Hakko Kirin Co., Ltd. Method for purifying protein using amino acid
RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
TWI812066B (zh) 2010-11-30 2023-08-11 日商中外製藥股份有限公司 具有鈣依存性的抗原結合能力之抗體
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
GB201109238D0 (en) * 2011-06-01 2011-07-13 Antitope Ltd Antibodies
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9650411B2 (en) 2012-08-07 2017-05-16 Kyowa Hakko Kirin Co., Ltd. Method of purifying protein
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
HK1211981A1 (en) 2012-09-02 2016-06-03 Abbvie Inc. Methods to control protein heterogeneity
SG11201507230PA (en) 2013-03-12 2015-10-29 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
AR095199A1 (es) 2013-03-15 2015-09-30 Genzyme Corp Anticuerpos anti-cd52
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
BR112016014824A2 (pt) 2013-12-27 2017-09-19 Chugai Pharmaceutical Co Ltd Método para purificar anticorpo que tem ponto isoelétrico baixo
KR101860280B1 (ko) 2014-12-19 2018-05-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
CN114773470A (zh) 2015-02-05 2022-07-22 中外制药株式会社 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il-8-结合抗体及其应用
WO2017022651A1 (ja) 2015-07-31 2017-02-09 中外製薬株式会社 アニオン性ポリマーによる抗体を含有する組成物の精製方法
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
US10688412B2 (en) 2016-07-25 2020-06-23 Cehpalon, Inc. Affinity chromatography wash buffer
TWI693940B (zh) 2016-08-05 2020-05-21 日商中外製藥股份有限公司 Ｉｌ-８相關疾病之治療用或預防用組成物
CN113646066B (zh) 2019-03-29 2024-05-31 旭化成医疗株式会社 蛋白质的纯化方法
US12383884B2 (en) 2019-04-08 2025-08-12 Asahi Kasei Medical Co., Ltd. Polyamide medium for purifying protein-containing solution and method for producing polyamide medium
JP7583411B2 (ja) 2019-04-10 2024-11-14 中外製薬株式会社 Ｆｃ領域改変抗体の精製方法
CN117241881A (zh) 2021-06-10 2023-12-15 三菱化学株式会社 合成吸附剂、抗体的纯化方法和抗体的制造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
WO1989007452A1 (en) * 1988-02-12 1989-08-24 Medical Research Council Improvements in or relating to antibodies

Also Published As

Publication number Publication date
FR2668164B1 (https=) 1995-04-14
ES2112865T5 (es) 2007-09-16
EP0504363B1 (en) 1998-01-21
AU4521897A (en) 1998-02-12
GR3026588T3 (en) 1998-07-31
IL99761A0 (en) 1992-08-18
BE1004226A5 (fr) 1992-10-13
FI922380A0 (fi) 1992-05-25
MY136210A (en) 2008-08-29
GB9022547D0 (en) 1990-11-28
BR1100358A (pt) 2000-03-28
CH681455A5 (https=) 1993-03-31
NZ240247A (en) 1994-03-25
MY119030A (en) 2005-03-31
KR920703108A (ko) 1992-12-17
IT1250064B (it) 1995-03-30
CA2069481C (en) 2003-07-29
ES2081742B1 (es) 1996-10-01
PT100988B (pt) 1999-08-31
GR910100425A (el) 1992-09-25
GB2253397A (en) 1992-09-09
JP2638680B2 (ja) 1997-08-06
TW283710B (https=) 1996-08-21
ES2081742A1 (es) 1996-03-01
CA2069481A1 (en) 1992-04-18
AU658926B2 (en) 1995-05-04
AU649078B2 (en) 1994-05-12
ZA926191B (en) 1993-04-16
EP0504363B2 (en) 2007-02-07
AU7024294A (en) 1995-01-05
ITRM910788A0 (it) 1991-10-16
AU2532192A (en) 1993-02-11
DE69128774T2 (de) 1998-06-04
AU716402B2 (en) 2000-02-24
ATA900791A (de) 1996-06-15
PT100988A (pt) 1994-02-28
LU88122A1 (fr) 1993-03-15
MX9203794A (es) 1992-07-01
FI922380L (fi) 1992-05-25
FR2668164A1 (fr) 1992-04-24
FR2677997A1 (fr) 1992-12-24
DK0504363T4 (da) 2007-05-29
HUT64601A (en) 1994-01-28
AU8729491A (en) 1992-05-20
DE69128774T3 (de) 2007-08-16
IL102726A (en) 2002-08-14
GR920100471A (el) 1994-06-30
EP0504363A1 (en) 1992-09-23
FI922824A0 (fi) 1992-06-17
GB9209529D0 (en) 1992-07-01
HU9202000D0 (en) 1992-10-28
US5644036A (en) 1997-07-01
PT99248B (pt) 1999-04-30
PT99248A (pt) 1993-06-30
FI110002B (fi) 2002-11-15
JPH05504579A (ja) 1993-07-15
WO1992007084A1 (en) 1992-04-30
IL102726A0 (en) 1993-01-31
ZA918259B (en) 1993-04-16
ATE162552T1 (de) 1998-02-15
FI110003B (fi) 2002-11-15
ITRM910788A1 (it) 1993-04-16
CH681305A5 (https=) 1993-02-26
KR100193314B1 (ko) 1999-06-15
NZ244114A (en) 1995-06-27
FI922824L (fi) 1992-06-17
DK0504363T3 (da) 1998-09-21
DE69128774D1 (de) 1998-02-26
ES2112865T3 (es) 1998-04-16
IE913560A1 (en) 1992-04-22

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