KR940019700A - 락톤 화합물 및 그의 제조방법 - Google Patents

락톤 화합물 및 그의 제조방법 Download PDF

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Publication number
KR940019700A
KR940019700A KR1019940002115A KR19940002115A KR940019700A KR 940019700 A KR940019700 A KR 940019700A KR 1019940002115 A KR1019940002115 A KR 1019940002115A KR 19940002115 A KR19940002115 A KR 19940002115A KR 940019700 A KR940019700 A KR 940019700A
Authority
KR
South Korea
Prior art keywords
configuration
asymmetric center
lactone
compound
dihydroxy
Prior art date
Application number
KR1019940002115A
Other languages
English (en)
Korean (ko)
Inventor
다베 마사야스
마나베 겐지
도미모리 코지
하자또 아쯔오
다께노우찌 오사미
아즈마 요시아끼
Original Assignee
히로시 이따가끼
데이진 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 히로시 이따가끼, 데이진 가부시끼가이샤 filed Critical 히로시 이따가끼
Publication of KR940019700A publication Critical patent/KR940019700A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
KR1019940002115A 1993-02-05 1994-02-04 락톤 화합물 및 그의 제조방법 KR940019700A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP18703/1993 1993-02-05
JP1870393 1993-02-05
JP68434/1993 1993-03-26
JP6843493 1993-03-26

Publications (1)

Publication Number Publication Date
KR940019700A true KR940019700A (ko) 1994-09-14

Family

ID=26355421

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940002115A KR940019700A (ko) 1993-02-05 1994-02-04 락톤 화합물 및 그의 제조방법

Country Status (11)

Country Link
US (1) US5604257A (ja)
EP (1) EP0619305B1 (ja)
JP (1) JP3588369B2 (ja)
KR (1) KR940019700A (ja)
CN (1) CN1055922C (ja)
AT (1) ATE154008T1 (ja)
AU (1) AU686578B2 (ja)
CA (1) CA2114830C (ja)
DE (1) DE69403541T2 (ja)
DK (1) DK0619305T3 (ja)
TW (1) TW364905B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0854139B1 (en) * 1994-06-07 2001-09-05 Teijin Limited Vitamin D3 derivative and production process thereof
US6020500A (en) * 1995-08-22 2000-02-01 The Lubrizol Corporation Hydroxy-substituted monolactones useful as intermediates for preparing lubricating oil and fuel additives
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP3020141B2 (ja) * 1996-10-07 2000-03-15 株式会社富士薬品 経鼻投与用製剤
EP1609469A3 (en) * 1996-12-13 2009-07-29 ZymoGenetics, Inc. Compositions and methods for stimulating bone growth
EP0944312B9 (en) * 1996-12-13 2006-07-05 ZymoGenetics, Inc. Compositions and methods for stimulating bone growth
US6080779A (en) * 1996-12-13 2000-06-27 Osteoscreen, Inc. Compositions and methods for stimulating bone growth
US6376476B1 (en) * 1996-12-13 2002-04-23 Zymogenetics Corporation Isoprenoid pathway inhibitors for stimulating bone growth
AUPP332898A0 (en) 1998-05-04 1998-05-28 Unisearch Limited Pharmaceutical composition
KR100676106B1 (ko) * 1998-10-23 2007-02-28 데이진 가부시키가이샤 비타민 ｄ3 유도체 및 그것을 사용하는 염증성 호흡기질환 치료제
US7041309B2 (en) * 2002-06-13 2006-05-09 Neuropro Technologies, Inc. Spinal fusion using an HMG-CoA reductase inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3247836A1 (de) * 1981-12-29 1983-07-07 Teijin Ltd., Osaka Arzneimittel und verwendung derselben zur steuerung der serumcalciumkonzentration bei warmbluetern
JPS58118516A (ja) * 1981-12-29 1983-07-14 Teijin Ltd １α，２５−ジヒドロキシビタミンＤ↓３−２６，２３−ラクトンを含有するカルシユウム調節剤
JPS58210011A (ja) * 1982-05-31 1983-12-07 Kureha Chem Ind Co Ltd 抗腫瘍剤
JPS60185715A (ja) * 1984-03-05 1985-09-21 Teijin Ltd 骨形成促進剤
JPS62175496A (ja) * 1986-01-30 1987-08-01 Teijin Ltd ステロイド化合物及びその製造法

Also Published As

Publication number Publication date
EP0619305A1 (en) 1994-10-12
EP0619305B1 (en) 1997-06-04
ATE154008T1 (de) 1997-06-15
CN1108244A (zh) 1995-09-13
DK0619305T3 (da) 1997-07-07
AU686578B2 (en) 1998-02-12
US5604257A (en) 1997-02-18
TW364905B (en) 1999-07-21
CN1055922C (zh) 2000-08-30
JP3588369B2 (ja) 2004-11-10
JPH06329696A (ja) 1994-11-29
DE69403541T2 (de) 1997-09-25
CA2114830A1 (en) 1994-08-06
AU5486694A (en) 1994-08-11
DE69403541D1 (de) 1997-07-10
CA2114830C (en) 2000-06-06

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