KR910008202B1 - 벤즈아미드 유도체의 제조방법 - Google Patents

벤즈아미드 유도체의 제조방법 Download PDF

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Publication number
KR910008202B1
KR910008202B1 KR1019840001083A KR840001083A KR910008202B1 KR 910008202 B1 KR910008202 B1 KR 910008202B1 KR 1019840001083 A KR1019840001083 A KR 1019840001083A KR 840001083 A KR840001083 A KR 840001083A KR 910008202 B1 KR910008202 B1 KR 910008202B1
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KR
South Korea
Prior art keywords
formula
acid
compound
mol
hydrogen
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Expired
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KR1019840001083A
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English (en)
Korean (ko)
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KR840009077A (ko
Inventor
다 프라다 모제
주스 레나토
키부르츠 에밀리오
찰스 뷔스 피에르
Original Assignee
에프. 호프만-라 롯슈 에이지
페터 유레흐, 프리돌린 클라우스너
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Application filed by 에프. 호프만-라 롯슈 에이지, 페터 유레흐, 프리돌린 클라우스너 filed Critical 에프. 호프만-라 롯슈 에이지
Publication of KR840009077A publication Critical patent/KR840009077A/ko
Application granted granted Critical
Publication of KR910008202B1 publication Critical patent/KR910008202B1/ko
Expired legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019840001083A 1983-03-03 1984-03-03 벤즈아미드 유도체의 제조방법 Expired KR910008202B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1150/83 1983-03-03
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Publications (2)

Publication Number Publication Date
KR840009077A KR840009077A (ko) 1984-12-24
KR910008202B1 true KR910008202B1 (ko) 1991-10-11

Family

ID=4203649

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840001083A Expired KR910008202B1 (ko) 1983-03-03 1984-03-03 벤즈아미드 유도체의 제조방법

Country Status (28)

Country Link
JP (1) JPS59167552A (enrdf_load_stackoverflow)
KR (1) KR910008202B1 (enrdf_load_stackoverflow)
AR (1) AR243155A1 (enrdf_load_stackoverflow)
AT (1) AT390948B (enrdf_load_stackoverflow)
AU (2) AU570431B2 (enrdf_load_stackoverflow)
BE (1) BE899059A (enrdf_load_stackoverflow)
CA (1) CA1252794A (enrdf_load_stackoverflow)
CH (1) CH653670A5 (enrdf_load_stackoverflow)
DE (1) DE3407654C2 (enrdf_load_stackoverflow)
DK (1) DK166382C (enrdf_load_stackoverflow)
ES (3) ES8504680A1 (enrdf_load_stackoverflow)
FI (1) FI79297C (enrdf_load_stackoverflow)
FR (1) FR2541996B1 (enrdf_load_stackoverflow)
GB (1) GB2135998B (enrdf_load_stackoverflow)
GR (1) GR81866B (enrdf_load_stackoverflow)
HU (1) HU193556B (enrdf_load_stackoverflow)
IE (1) IE57004B1 (enrdf_load_stackoverflow)
IL (1) IL71078A (enrdf_load_stackoverflow)
IT (1) IT1173365B (enrdf_load_stackoverflow)
LU (1) LU85231A1 (enrdf_load_stackoverflow)
MC (1) MC1568A1 (enrdf_load_stackoverflow)
NL (1) NL8400459A (enrdf_load_stackoverflow)
NO (1) NO165999C (enrdf_load_stackoverflow)
NZ (1) NZ207272A (enrdf_load_stackoverflow)
PH (1) PH19623A (enrdf_load_stackoverflow)
PT (1) PT78187B (enrdf_load_stackoverflow)
SE (1) SE466447B (enrdf_load_stackoverflow)
ZA (1) ZA841394B (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1261335A (en) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Ethylenediamine monoamide derivatives
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
NZ219974A (en) * 1986-04-22 1989-08-29 Goedecke Ag N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
FR2642972B1 (fr) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation
WO2014155184A1 (en) * 2013-03-28 2014-10-02 Rhenovia Pharma Treatment for parkinson's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342679A (en) * 1967-09-19 Parts by weight of acid chloride to react with parts of amine in
FR6557M (enrdf_load_stackoverflow) * 1967-06-20 1968-12-23 Ile De France
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
DE2616486A1 (de) * 1976-04-14 1977-11-03 Basf Ag Farbstoffe der perylentetracarbonsaeurediimidreihe
CA1206964A (en) * 1980-11-12 1986-07-02 Nobuo Shinma Tetra-substituted benzene derivatives
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
IL69997A0 (en) * 1983-01-03 1984-01-31 Miles Lab Procainamide and n-acetylprocainamide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Also Published As

Publication number Publication date
AT390948B (de) 1990-07-25
CA1252794A (en) 1989-04-18
FI840734A0 (fi) 1984-02-22
AR243155A1 (es) 1993-07-30
IT8419778A0 (it) 1984-02-23
GB2135998B (en) 1986-09-24
IE57004B1 (en) 1992-03-11
GB8405486D0 (en) 1984-04-04
ES537046A0 (es) 1985-08-16
IL71078A0 (en) 1984-05-31
ES530230A0 (es) 1985-05-01
NL8400459A (nl) 1984-10-01
ES8506600A1 (es) 1985-08-16
CH653670A5 (de) 1986-01-15
IT1173365B (it) 1987-06-24
HU193556B (en) 1987-10-28
ES8506601A1 (es) 1985-08-16
GB2135998A (en) 1984-09-12
IE840512L (en) 1984-09-03
MC1568A1 (fr) 1985-02-04
BE899059A (fr) 1984-09-03
NZ207272A (en) 1987-07-31
FI79297C (fi) 1989-12-11
LU85231A1 (de) 1985-09-12
NO840797L (no) 1984-09-04
PH19623A (enrdf_load_stackoverflow) 1986-06-04
GR81866B (enrdf_load_stackoverflow) 1984-12-12
ZA841394B (en) 1985-06-26
FI79297B (fi) 1989-08-31
FI840734L (fi) 1984-09-04
AU570431B2 (en) 1988-03-17
DK166382B (da) 1993-05-10
ES537045A0 (es) 1985-08-16
KR840009077A (ko) 1984-12-24
NO165999C (no) 1991-05-15
PT78187A (en) 1984-04-01
DK147584A (da) 1984-09-04
NO165999B (no) 1991-02-04
FR2541996A1 (fr) 1984-09-07
DK166382C (da) 1993-09-27
DK147584D0 (da) 1984-02-29
DE3407654C2 (de) 1994-04-07
ES8504680A1 (es) 1985-05-01
SE8401190D0 (sv) 1984-03-02
IL71078A (en) 1987-12-31
JPS59167552A (ja) 1984-09-21
ATA72484A (de) 1990-01-15
AU2506684A (en) 1984-09-06
JPH0430389B2 (enrdf_load_stackoverflow) 1992-05-21
SE466447B (sv) 1992-02-17
PT78187B (en) 1986-08-05
SE8401190L (sv) 1984-09-04
DE3407654A1 (de) 1984-09-06
FR2541996B1 (fr) 1987-12-11
AU609758B2 (en) 1991-05-09
AU8307987A (en) 1988-06-16

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