ES8504680A1 - Un procedimiento para la preparacion de derivados de benzamida - Google Patents

Un procedimiento para la preparacion de derivados de benzamida

Info

Publication number
ES8504680A1
ES8504680A1 ES530230A ES530230A ES8504680A1 ES 8504680 A1 ES8504680 A1 ES 8504680A1 ES 530230 A ES530230 A ES 530230A ES 530230 A ES530230 A ES 530230A ES 8504680 A1 ES8504680 A1 ES 8504680A1
Authority
ES
Spain
Prior art keywords
formula
benzamide derivatives
ryr
ethylendiamine
parkinsonism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530230A
Other languages
English (en)
Spanish (es)
Other versions
ES530230A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES530230A0 publication Critical patent/ES530230A0/es
Publication of ES8504680A1 publication Critical patent/ES8504680A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES530230A 1983-03-03 1984-03-02 Un procedimiento para la preparacion de derivados de benzamida Expired ES8504680A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Publications (2)

Publication Number Publication Date
ES530230A0 ES530230A0 (es) 1985-05-01
ES8504680A1 true ES8504680A1 (es) 1985-05-01

Family

ID=4203649

Family Applications (3)

Application Number Title Priority Date Filing Date
ES530230A Expired ES8504680A1 (es) 1983-03-03 1984-03-02 Un procedimiento para la preparacion de derivados de benzamida
ES537045A Expired ES8506600A1 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida
ES537046A Granted ES537046A0 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES537045A Expired ES8506600A1 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida
ES537046A Granted ES537046A0 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida

Country Status (28)

Country Link
JP (1) JPS59167552A (enrdf_load_stackoverflow)
KR (1) KR910008202B1 (enrdf_load_stackoverflow)
AR (1) AR243155A1 (enrdf_load_stackoverflow)
AT (1) AT390948B (enrdf_load_stackoverflow)
AU (2) AU570431B2 (enrdf_load_stackoverflow)
BE (1) BE899059A (enrdf_load_stackoverflow)
CA (1) CA1252794A (enrdf_load_stackoverflow)
CH (1) CH653670A5 (enrdf_load_stackoverflow)
DE (1) DE3407654C2 (enrdf_load_stackoverflow)
DK (1) DK166382C (enrdf_load_stackoverflow)
ES (3) ES8504680A1 (enrdf_load_stackoverflow)
FI (1) FI79297C (enrdf_load_stackoverflow)
FR (1) FR2541996B1 (enrdf_load_stackoverflow)
GB (1) GB2135998B (enrdf_load_stackoverflow)
GR (1) GR81866B (enrdf_load_stackoverflow)
HU (1) HU193556B (enrdf_load_stackoverflow)
IE (1) IE57004B1 (enrdf_load_stackoverflow)
IL (1) IL71078A (enrdf_load_stackoverflow)
IT (1) IT1173365B (enrdf_load_stackoverflow)
LU (1) LU85231A1 (enrdf_load_stackoverflow)
MC (1) MC1568A1 (enrdf_load_stackoverflow)
NL (1) NL8400459A (enrdf_load_stackoverflow)
NO (1) NO165999C (enrdf_load_stackoverflow)
NZ (1) NZ207272A (enrdf_load_stackoverflow)
PH (1) PH19623A (enrdf_load_stackoverflow)
PT (1) PT78187B (enrdf_load_stackoverflow)
SE (1) SE466447B (enrdf_load_stackoverflow)
ZA (1) ZA841394B (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1261335A (en) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Ethylenediamine monoamide derivatives
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
NZ219974A (en) * 1986-04-22 1989-08-29 Goedecke Ag N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
FR2642972B1 (fr) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation
WO2014155184A1 (en) * 2013-03-28 2014-10-02 Rhenovia Pharma Treatment for parkinson's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342679A (en) * 1967-09-19 Parts by weight of acid chloride to react with parts of amine in
FR6557M (enrdf_load_stackoverflow) * 1967-06-20 1968-12-23 Ile De France
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
DE2616486A1 (de) * 1976-04-14 1977-11-03 Basf Ag Farbstoffe der perylentetracarbonsaeurediimidreihe
CA1206964A (en) * 1980-11-12 1986-07-02 Nobuo Shinma Tetra-substituted benzene derivatives
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
IL69997A0 (en) * 1983-01-03 1984-01-31 Miles Lab Procainamide and n-acetylprocainamide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Also Published As

Publication number Publication date
FI840734L (fi) 1984-09-04
DK166382C (da) 1993-09-27
BE899059A (fr) 1984-09-03
KR840009077A (ko) 1984-12-24
GR81866B (enrdf_load_stackoverflow) 1984-12-12
IL71078A (en) 1987-12-31
SE8401190L (sv) 1984-09-04
GB2135998A (en) 1984-09-12
ES8506601A1 (es) 1985-08-16
FR2541996B1 (fr) 1987-12-11
ES537045A0 (es) 1985-08-16
GB8405486D0 (en) 1984-04-04
FI79297C (fi) 1989-12-11
IE57004B1 (en) 1992-03-11
PT78187A (en) 1984-04-01
NO840797L (no) 1984-09-04
PH19623A (enrdf_load_stackoverflow) 1986-06-04
ES8506600A1 (es) 1985-08-16
NZ207272A (en) 1987-07-31
IT1173365B (it) 1987-06-24
AT390948B (de) 1990-07-25
AU2506684A (en) 1984-09-06
AU609758B2 (en) 1991-05-09
AU8307987A (en) 1988-06-16
NO165999B (no) 1991-02-04
ES537046A0 (es) 1985-08-16
HU193556B (en) 1987-10-28
IL71078A0 (en) 1984-05-31
CA1252794A (en) 1989-04-18
IE840512L (en) 1984-09-03
MC1568A1 (fr) 1985-02-04
ES530230A0 (es) 1985-05-01
JPS59167552A (ja) 1984-09-21
ZA841394B (en) 1985-06-26
DK166382B (da) 1993-05-10
KR910008202B1 (ko) 1991-10-11
DK147584A (da) 1984-09-04
GB2135998B (en) 1986-09-24
SE8401190D0 (sv) 1984-03-02
CH653670A5 (de) 1986-01-15
FR2541996A1 (fr) 1984-09-07
LU85231A1 (de) 1985-09-12
AR243155A1 (es) 1993-07-30
FI840734A0 (fi) 1984-02-22
NO165999C (no) 1991-05-15
DK147584D0 (da) 1984-02-29
SE466447B (sv) 1992-02-17
DE3407654A1 (de) 1984-09-06
ATA72484A (de) 1990-01-15
PT78187B (en) 1986-08-05
JPH0430389B2 (enrdf_load_stackoverflow) 1992-05-21
FI79297B (fi) 1989-08-31
NL8400459A (nl) 1984-10-01
AU570431B2 (en) 1988-03-17
IT8419778A0 (it) 1984-02-23
DE3407654C2 (de) 1994-04-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519