KR910004450B1 - 3-아크릴아미노메틸이미다조[1,2-a]피리딘 유도체, 그의 제법 및 그를 포함하는 의약조성물 - Google Patents

3-아크릴아미노메틸이미다조[1,2-a]피리딘 유도체, 그의 제법 및 그를 포함하는 의약조성물 Download PDF

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Publication number
KR910004450B1
KR910004450B1 KR1019850005660A KR850005660A KR910004450B1 KR 910004450 B1 KR910004450 B1 KR 910004450B1 KR 1019850005660 A KR1019850005660 A KR 1019850005660A KR 850005660 A KR850005660 A KR 850005660A KR 910004450 B1 KR910004450 B1 KR 910004450B1
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South Korea
Prior art keywords
formula
methyl
hydrogen
amide
chlorine
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Expired
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KR1019850005660A
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Korean (ko)
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KR860001809A (ko
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제오르즈 파스칼
지론 클로디
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신 떼라보
에 뚜레-레메뜨르
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019850005660A 1984-08-07 1985-08-06 3-아크릴아미노메틸이미다조[1,2-a]피리딘 유도체, 그의 제법 및 그를 포함하는 의약조성물 Expired KR910004450B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR12447 1984-08-07
FR84/12447 1984-08-07
FR8412447A FR2568880B1 (fr) 1984-08-07 1984-08-07 Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
KR860001809A KR860001809A (ko) 1986-03-22
KR910004450B1 true KR910004450B1 (ko) 1991-06-29

Family

ID=9306856

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KR1019850005660A Expired KR910004450B1 (ko) 1984-08-07 1985-08-06 3-아크릴아미노메틸이미다조[1,2-a]피리딘 유도체, 그의 제법 및 그를 포함하는 의약조성물

Country Status (23)

Country Link
US (1) US4650796A (enExample)
EP (1) EP0172096B1 (enExample)
JP (1) JPS6147485A (enExample)
KR (1) KR910004450B1 (enExample)
AR (1) AR241185A1 (enExample)
AT (1) ATE40365T1 (enExample)
AU (1) AU575190B2 (enExample)
CA (1) CA1261830A (enExample)
CZ (1) CZ357691A3 (enExample)
DE (1) DE3567867D1 (enExample)
DK (1) DK163923C (enExample)
ES (1) ES8604592A1 (enExample)
FI (1) FI80696C (enExample)
FR (1) FR2568880B1 (enExample)
GR (1) GR851928B (enExample)
HU (1) HU193799B (enExample)
IE (1) IE58347B1 (enExample)
IL (1) IL76020A (enExample)
MX (1) MX160845A (enExample)
NO (1) NO162189C (enExample)
NZ (1) NZ213013A (enExample)
PT (1) PT80921B (enExample)
ZA (1) ZA855939B (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3769333D1 (de) * 1986-01-22 1991-05-23 Synthelabo Acylaminomethylimidazo(1,2-a)pyrimidinderivate, ihre herstellung und therapeutische verwendung.
FR2593818B1 (fr) * 1986-02-05 1988-04-29 Synthelabo Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
FR2593180B1 (fr) * 1986-01-22 1990-10-26 Synthelabo Derives d'acylaminomethyl-1 imidazo (1,2-a)quinoleines, leur preparation et leur application en therapeutique
US4990506A (en) * 1986-02-05 1991-02-05 Synthelabo 3-(acylaminomethyl)imidazo[1,2-a]pyridine derivatives and their application in therapy
FR2606409B1 (fr) * 1986-11-07 1989-05-05 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
ES2026666T3 (es) * 1987-03-27 1992-05-01 Synthelabo Procedimiento para preparar derivados de imidazopiridinas.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2654933B1 (fr) * 1989-11-30 1994-06-10 Synthelabo Utilisation d'une imidazopyridine pour la fabrication de medicaments anesthesiques.
KR910011852A (ko) * 1989-12-04 1991-08-07 폴 디. 매튜카이티스 신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
US5716964A (en) * 1989-12-04 1998-02-10 G.D. Searle & Co. Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
IE904346A1 (en) * 1989-12-04 1991-06-05 Searle & Co IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
US5464843A (en) * 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AUPP278498A0 (en) 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
DE10019714A1 (de) * 2000-04-20 2002-01-10 Gruenenthal Gmbh Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
WO2002002557A2 (en) * 2000-06-30 2002-01-10 Neurogen Corporation 2-phenylimidazo[1,2-a]pyridine derivatives: a new class of gaba brain receptor ligands
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10247269A1 (de) 2002-10-10 2004-04-22 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yl-methylamine
JP2007509960A (ja) * 2003-10-28 2007-04-19 セプラコア インコーポレーテッド イミダゾ［１，２−ａ］ピリジン抗不安薬
WO2005081749A2 (en) * 2004-01-23 2005-09-09 Avanir Pharmaceuticals, Inc. Neutralizing human antibodies to anthraxtoxin
FR2874611B1 (fr) * 2004-08-31 2006-11-17 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1814880B1 (en) * 2004-11-11 2009-01-28 Ferrer Internacional, S.A. Imidazo[1,2-a]pyridine compounds, compositions, uses and methods related thereto
ES2441178T3 (es) 2005-06-01 2014-02-03 Ucb Pharma, S.A. Derivados de 2-oxo-1-pirrolidina, procedimientos para prepararlos y el uso terapéutico de los mismos sobre el sistema nervioso central
EP2152262A2 (en) * 2007-04-27 2010-02-17 UCB Pharma, S.A. New heterocyclic derivatives useful for the treatment of cns disorders
WO2009143156A2 (en) * 2008-05-19 2009-11-26 Sepracor Inc. IMIDAZO[1,2-a]PYRIDINE COMPOUNDS
DK2376490T3 (da) * 2008-12-04 2013-04-15 Proximagen Ltd Imidazopyridinforbindelser
SG11201509650YA (en) 2013-05-24 2015-12-30 Iomet Pharma Ltd Slc2a transporter inhibitors
US12282014B2 (en) 2015-11-19 2025-04-22 Dana-Farber Cancer Institute, Inc. Methods of identifying compounds that interfere with ERG-driven misguidance of BAF complexes in TMPRSS2-ERG driven prostate cancers
EP3746124A4 (en) 2018-01-30 2021-10-27 Foghorn Therapeutics Inc. COMPOUNDS AND THEIR USES
US12473334B2 (en) 2018-10-17 2025-11-18 Dana-Farber Cancer Institute, Inc. SWI/SNF family chromatin remodeling complexes and uses thereof
JP2022515879A (ja) * 2018-12-29 2022-02-22 武漢朗来科技発展有限公司 複素環式化合物、中間体、その製造方法及び応用 本願は、出願日が２０１８年１２月２９日の中国特許出願ｃｎ ２０１８１１６４２３１９、出願日が２０１９年０５月２４日の中国特許出願ｃｎ２０１９１０４４０２１４．３及び出願日が２０１９年１０月２４日の中国特許出願ｃｎ２０１９１１０１６１５８．７に基づいて優先権を主張する。また、上記中国特許出願の全文は本願に援用される。
WO2020160196A1 (en) 2019-01-29 2020-08-06 Foghorn Therapeutics Inc. Compounds and uses thereof
BR112022015004A2 (pt) 2020-01-29 2022-09-20 Foghorn Therapeutics Inc Composto, composição farmacêutica, métodos para diminuir a atividade de um complexo baf, induzir apoptose, reduzir o crescimento tumoral, suprimir a progressão e a colonização metastática do câncer e reduzir o nível e/ou a atividade de brg1 e/ou brm em um câncer e métodos de tratamento e de inibição de brm e brg1
EP4096668A4 (en) * 2020-01-29 2024-02-28 Foghorn Therapeutics Inc. Compounds and uses thereof
US12383555B2 (en) 2020-05-20 2025-08-12 Foghorn Therapeutics Inc. Methods of treating cancers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB991589A (en) * 1963-04-30 1965-05-12 Selvi & C Lab Bioterapico Novel [1,2-ª‡]imidazopyridines and a process for the manufacture thereof
GB1076089A (en) * 1965-11-09 1967-07-19 Selvi & C Lab Bioterapico New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

Also Published As

Publication number Publication date
DK163923C (da) 1992-09-14
ATE40365T1 (de) 1989-02-15
FI80696B (fi) 1990-03-30
DK356885D0 (da) 1985-08-06
JPS6147485A (ja) 1986-03-07
IE58347B1 (en) 1993-09-08
AR241185A1 (es) 1992-01-31
EP0172096B1 (fr) 1989-01-25
FI853026A0 (fi) 1985-08-06
FI80696C (fi) 1990-07-10
FI853026L (fi) 1986-02-08
KR860001809A (ko) 1986-03-22
ES8604592A1 (es) 1986-02-01
EP0172096A1 (fr) 1986-02-19
PT80921B (pt) 1987-12-30
DK356885A (da) 1986-02-08
GR851928B (enExample) 1985-12-09
US4650796A (en) 1987-03-17
CA1261830A (en) 1989-09-26
IL76020A0 (en) 1985-12-31
NO162189B (no) 1989-08-14
DK163923B (da) 1992-04-21
AU575190B2 (en) 1988-07-21
ES545928A0 (es) 1986-02-01
JPH0523267B2 (enExample) 1993-04-02
CZ357691A3 (en) 1993-06-16
MX160845A (es) 1990-05-31
NZ213013A (en) 1988-05-30
AU4580985A (en) 1986-02-13
PT80921A (fr) 1985-09-01
HUT38637A (en) 1986-06-30
ZA855939B (en) 1986-03-26
HU193799B (en) 1987-11-30
NO853100L (no) 1986-02-10
FR2568880A1 (fr) 1986-02-14
DE3567867D1 (en) 1989-03-02
IL76020A (en) 1989-01-31
NO162189C (no) 1989-11-29
FR2568880B1 (fr) 1986-12-12
IE851937L (en) 1986-02-07

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