KR910002536B1 - 플라티늄-디아민 착화물의 제조방법 - Google Patents

플라티늄-디아민 착화물의 제조방법 Download PDF

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Publication number
KR910002536B1
KR910002536B1 KR1019830004987A KR830004987A KR910002536B1 KR 910002536 B1 KR910002536 B1 KR 910002536B1 KR 1019830004987 A KR1019830004987 A KR 1019830004987A KR 830004987 A KR830004987 A KR 830004987A KR 910002536 B1 KR910002536 B1 KR 910002536B1
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KR
South Korea
Prior art keywords
compound
formula
groups
platinum
general formula
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Expired
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KR1019830004987A
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English (en)
Korean (ko)
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KR840006492A (ko
Inventor
베르빅 프랑소와
베르그 쟝
쟝 불텐 에릭
Original Assignee
네덜란드즈 세트랄 오르가니세티 보르 퇴게파스트-네툴베텐 샤펠리젝 온 더족
베. 아. 드종
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Publication of KR840006492A publication Critical patent/KR840006492A/ko
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Publication of KR910002536B1 publication Critical patent/KR910002536B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019830004987A 1982-10-21 1983-10-21 플라티늄-디아민 착화물의 제조방법 Expired KR910002536B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8204067 1982-10-21
NL8204067A NL8204067A (nl) 1982-10-21 1982-10-21 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.

Publications (2)

Publication Number Publication Date
KR840006492A KR840006492A (ko) 1984-11-30
KR910002536B1 true KR910002536B1 (ko) 1991-04-23

Family

ID=19840444

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830004987A Expired KR910002536B1 (ko) 1982-10-21 1983-10-21 플라티늄-디아민 착화물의 제조방법

Country Status (28)

Country Link
JP (1) JPS5993091A (enrdf_load_stackoverflow)
KR (1) KR910002536B1 (enrdf_load_stackoverflow)
AT (1) AT390610B (enrdf_load_stackoverflow)
AU (1) AU562964B2 (enrdf_load_stackoverflow)
BE (1) BE898058A (enrdf_load_stackoverflow)
CA (1) CA1229618A (enrdf_load_stackoverflow)
CH (1) CH658244A5 (enrdf_load_stackoverflow)
CS (1) CS242888B2 (enrdf_load_stackoverflow)
DD (1) DD217522A5 (enrdf_load_stackoverflow)
DE (1) DE3337333A1 (enrdf_load_stackoverflow)
DK (2) DK483083A (enrdf_load_stackoverflow)
ES (1) ES8406498A1 (enrdf_load_stackoverflow)
FI (1) FI76351C (enrdf_load_stackoverflow)
FR (1) FR2534907B1 (enrdf_load_stackoverflow)
GB (1) GB2128615B (enrdf_load_stackoverflow)
GR (1) GR79652B (enrdf_load_stackoverflow)
HU (1) HU188035B (enrdf_load_stackoverflow)
IE (1) IE56124B1 (enrdf_load_stackoverflow)
IT (1) IT1169858B (enrdf_load_stackoverflow)
LU (1) LU85054A1 (enrdf_load_stackoverflow)
NL (1) NL8204067A (enrdf_load_stackoverflow)
NO (1) NO171276C (enrdf_load_stackoverflow)
NZ (1) NZ206018A (enrdf_load_stackoverflow)
PH (1) PH24077A (enrdf_load_stackoverflow)
PT (1) PT77542B (enrdf_load_stackoverflow)
SE (1) SE8305783L (enrdf_load_stackoverflow)
YU (1) YU43554B (enrdf_load_stackoverflow)
ZA (1) ZA837857B (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
EP0262498B1 (de) * 1986-10-03 1990-05-30 ASTA Pharma Aktiengesellschaft Diamin-platin (II)-Komplexverbindungen mit einem hydroxylierten 2-Phenyl-Indolring
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
CN102924528B (zh) * 2012-10-29 2015-04-15 东南大学 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
NL189358C (nl) * 1978-07-06 1993-03-16 Tno Werkwijze voor het bereiden van een geneesmiddel voor de behandeling van kanker, alsmede een van een 1,3-alkaandiamine afgeleid platina-diamminecomplex.
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes
NZ197104A (en) * 1980-05-27 1984-05-31 Bristol Myers Co Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives

Also Published As

Publication number Publication date
PT77542A (en) 1983-11-01
FI76351B (fi) 1988-06-30
JPH0244479B2 (enrdf_load_stackoverflow) 1990-10-04
CS775283A2 (en) 1985-08-15
AU2027583A (en) 1984-05-03
CH658244A5 (de) 1986-10-31
CA1229618A (en) 1987-11-24
FI833842A0 (fi) 1983-10-20
BE898058A (nl) 1984-04-24
NL8204067A (nl) 1984-05-16
CS242888B2 (en) 1986-05-15
GB2128615A (en) 1984-05-02
DK483083A (da) 1984-04-22
YU43554B (en) 1989-08-31
GB8328084D0 (en) 1983-11-23
GR79652B (enrdf_load_stackoverflow) 1984-10-31
YU210783A (en) 1986-08-31
DE3337333A1 (de) 1984-04-26
NZ206018A (en) 1986-02-21
JPS5993091A (ja) 1984-05-29
PH24077A (en) 1990-03-05
GB2128615B (en) 1986-07-16
ES526670A0 (es) 1984-07-01
NO833825L (no) 1984-04-24
ATA373083A (de) 1989-11-15
AU562964B2 (en) 1987-06-25
AT390610B (de) 1990-06-11
SE8305783L (sv) 1984-04-22
ZA837857B (en) 1984-06-27
ES8406498A1 (es) 1984-07-01
FR2534907A1 (fr) 1984-04-27
DD217522A5 (de) 1985-01-16
DK75592D0 (da) 1992-06-09
KR840006492A (ko) 1984-11-30
IE56124B1 (en) 1991-04-24
LU85054A1 (enrdf_load_stackoverflow) 1984-03-22
NO171276B (no) 1992-11-09
HU188035B (en) 1986-03-28
FI76351C (fi) 1988-10-10
IE832459L (en) 1984-04-21
FI833842L (fi) 1984-04-22
FR2534907B1 (fr) 1988-08-19
DK75592A (da) 1992-06-09
IT8323359A0 (it) 1983-10-19
IT1169858B (it) 1987-06-03
PT77542B (en) 1986-02-12
NO171276C (no) 1993-02-17
DK483083D0 (da) 1983-10-20
SE8305783D0 (sv) 1983-10-20

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