DK483083A - Platin-diamin komplekser og fremgangsmaade til fremstilling deraf - Google Patents

Platin-diamin komplekser og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK483083A
DK483083A DK483083A DK483083A DK483083A DK 483083 A DK483083 A DK 483083A DK 483083 A DK483083 A DK 483083A DK 483083 A DK483083 A DK 483083A DK 483083 A DK483083 A DK 483083A
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DK
Denmark
Prior art keywords
platin
procedures
producing
diamine complexes
diamine
Prior art date
Application number
DK483083A
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English (en)
Other versions
DK483083D0 (da
Inventor
Francois Verbeek
Jan Berg
Eric Jan Bulten
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of DK483083D0 publication Critical patent/DK483083D0/da
Publication of DK483083A publication Critical patent/DK483083A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK483083A 1982-10-21 1983-10-20 Platin-diamin komplekser og fremgangsmaade til fremstilling deraf DK483083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8204067A NL8204067A (nl) 1982-10-21 1982-10-21 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.

Publications (2)

Publication Number Publication Date
DK483083D0 DK483083D0 (da) 1983-10-20
DK483083A true DK483083A (da) 1984-04-22

Family

ID=19840444

Family Applications (2)

Application Number Title Priority Date Filing Date
DK483083A DK483083A (da) 1982-10-21 1983-10-20 Platin-diamin komplekser og fremgangsmaade til fremstilling deraf
DK075592A DK75592A (da) 1982-10-21 1992-06-09 Analogifremgangsmaade til fremstilling af platin-diamin komplekser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK075592A DK75592A (da) 1982-10-21 1992-06-09 Analogifremgangsmaade til fremstilling af platin-diamin komplekser

Country Status (28)

Country Link
JP (1) JPS5993091A (da)
KR (1) KR910002536B1 (da)
AT (1) AT390610B (da)
AU (1) AU562964B2 (da)
BE (1) BE898058A (da)
CA (1) CA1229618A (da)
CH (1) CH658244A5 (da)
CS (1) CS242888B2 (da)
DD (1) DD217522A5 (da)
DE (1) DE3337333A1 (da)
DK (2) DK483083A (da)
ES (1) ES8406498A1 (da)
FI (1) FI76351C (da)
FR (1) FR2534907B1 (da)
GB (1) GB2128615B (da)
GR (1) GR79652B (da)
HU (1) HU188035B (da)
IE (1) IE56124B1 (da)
IT (1) IT1169858B (da)
LU (1) LU85054A1 (da)
NL (1) NL8204067A (da)
NO (1) NO171276C (da)
NZ (1) NZ206018A (da)
PH (1) PH24077A (da)
PT (1) PT77542B (da)
SE (1) SE8305783L (da)
YU (1) YU43554B (da)
ZA (1) ZA837857B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
EP0262498B1 (de) * 1986-10-03 1990-05-30 ASTA Pharma Aktiengesellschaft Diamin-platin (II)-Komplexverbindungen mit einem hydroxylierten 2-Phenyl-Indolring
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
CN102924528B (zh) * 2012-10-29 2015-04-15 东南大学 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL189358C (nl) * 1978-07-06 1993-03-16 Tno Werkwijze voor het bereiden van een geneesmiddel voor de behandeling van kanker, alsmede een van een 1,3-alkaandiamine afgeleid platina-diamminecomplex.
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes
NZ197104A (en) * 1980-05-27 1984-05-31 Bristol Myers Co Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives

Also Published As

Publication number Publication date
KR910002536B1 (ko) 1991-04-23
FR2534907A1 (fr) 1984-04-27
IE832459L (en) 1984-04-21
AU562964B2 (en) 1987-06-25
FR2534907B1 (fr) 1988-08-19
GB8328084D0 (en) 1983-11-23
FI833842A (fi) 1984-04-22
CS775283A2 (en) 1985-08-15
NO833825L (no) 1984-04-24
SE8305783D0 (sv) 1983-10-20
DK75592D0 (da) 1992-06-09
ATA373083A (de) 1989-11-15
CH658244A5 (de) 1986-10-31
ES526670A0 (es) 1984-07-01
FI833842A0 (fi) 1983-10-20
GR79652B (da) 1984-10-31
NL8204067A (nl) 1984-05-16
JPS5993091A (ja) 1984-05-29
FI76351B (fi) 1988-06-30
NZ206018A (en) 1986-02-21
CA1229618A (en) 1987-11-24
GB2128615A (en) 1984-05-02
YU43554B (en) 1989-08-31
DD217522A5 (de) 1985-01-16
IT1169858B (it) 1987-06-03
AT390610B (de) 1990-06-11
ZA837857B (en) 1984-06-27
DK75592A (da) 1992-06-09
BE898058A (nl) 1984-04-24
NO171276C (no) 1993-02-17
DE3337333A1 (de) 1984-04-26
PT77542A (en) 1983-11-01
SE8305783L (sv) 1984-04-22
KR840006492A (ko) 1984-11-30
IE56124B1 (en) 1991-04-24
ES8406498A1 (es) 1984-07-01
HU188035B (en) 1986-03-28
IT8323359A0 (it) 1983-10-19
FI76351C (fi) 1988-10-10
DK483083D0 (da) 1983-10-20
PT77542B (en) 1986-02-12
AU2027583A (en) 1984-05-03
NO171276B (no) 1992-11-09
GB2128615B (en) 1986-07-16
LU85054A1 (da) 1984-03-22
YU210783A (en) 1986-08-31
CS242888B2 (en) 1986-05-15
JPH0244479B2 (da) 1990-10-04
PH24077A (en) 1990-03-05

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