ZA837857B - Platinum-diamine complexes,a process for the preparation thereof and a process for the preparation of a medical composition using such a complex for the treatment of cancer - Google Patents

Platinum-diamine complexes,a process for the preparation thereof and a process for the preparation of a medical composition using such a complex for the treatment of cancer

Info

Publication number
ZA837857B
ZA837857B ZA837857A ZA837857A ZA837857B ZA 837857 B ZA837857 B ZA 837857B ZA 837857 A ZA837857 A ZA 837857A ZA 837857 A ZA837857 A ZA 837857A ZA 837857 B ZA837857 B ZA 837857B
Authority
ZA
South Africa
Prior art keywords
preparation
platinum
cancer
complex
treatment
Prior art date
Application number
ZA837857A
Inventor
Francois Verbeek
Jan Berg
Eric Jan Bulten
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of ZA837857B publication Critical patent/ZA837857B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA837857A 1982-10-21 1983-10-21 Platinum-diamine complexes,a process for the preparation thereof and a process for the preparation of a medical composition using such a complex for the treatment of cancer ZA837857B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8204067A NL8204067A (en) 1982-10-21 1982-10-21 PLATINUM DIAMINE COMPLEXES, METHOD FOR PREPARING THE SAME, METHOD FOR PREPARING A MEDICINAL PRODUCT USING SUCH PLATINADIAMINE COMPLEX FOR THE TREATMENT OF CANCER, PREVENTLY PREVENTED.

Publications (1)

Publication Number Publication Date
ZA837857B true ZA837857B (en) 1984-06-27

Family

ID=19840444

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA837857A ZA837857B (en) 1982-10-21 1983-10-21 Platinum-diamine complexes,a process for the preparation thereof and a process for the preparation of a medical composition using such a complex for the treatment of cancer

Country Status (28)

Country Link
JP (1) JPS5993091A (en)
KR (1) KR910002536B1 (en)
AT (1) AT390610B (en)
AU (1) AU562964B2 (en)
BE (1) BE898058A (en)
CA (1) CA1229618A (en)
CH (1) CH658244A5 (en)
CS (1) CS242888B2 (en)
DD (1) DD217522A5 (en)
DE (1) DE3337333A1 (en)
DK (2) DK483083A (en)
ES (1) ES8406498A1 (en)
FI (1) FI76351C (en)
FR (1) FR2534907B1 (en)
GB (1) GB2128615B (en)
GR (1) GR79652B (en)
HU (1) HU188035B (en)
IE (1) IE56124B1 (en)
IT (1) IT1169858B (en)
LU (1) LU85054A1 (en)
NL (1) NL8204067A (en)
NO (1) NO171276C (en)
NZ (1) NZ206018A (en)
PH (1) PH24077A (en)
PT (1) PT77542B (en)
SE (1) SE8305783L (en)
YU (1) YU43554B (en)
ZA (1) ZA837857B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (en) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg CIS-PLATINUM COMPLEXES WITH A PENTAERYTHRITE DERIVATIVE AS A LIGAND, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENT CONTAINING THESE COMPOUNDS
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
DE3630497A1 (en) * 1986-09-08 1988-03-10 Behringwerke Ag CIS-PLATINUM COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS
ATE53217T1 (en) * 1986-10-03 1990-06-15 Asta Pharma Ag DIAMININE-PLATINUM (II) COMPLEX COMPOUNDS WITH A HYDROXYLATED 2-PHENYL-INDOLE RING.
JPS63203692A (en) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd Novel platinum complex
AT390065B (en) * 1987-10-08 1990-03-12 Behringwerke Ag cis-Platinum complexes, process for their preparation and pharmaceutical compositions containing these compounds
NL8802150A (en) * 1988-08-31 1990-03-16 Tno PLATINUM (II) DIAMINE COMPLEX, PROCESS FOR PREPARING THIS COMPOUND, PREPARATION WITH ANTI-TUMOR EFFECT, CONTAINING THIS COMPOUND AND FORMED PREPARATIONS WITH ANTI-TUMOR EFFECT.
NL8802149A (en) * 1988-08-31 1990-03-16 Tno PLATINUM (IV) DIAMINE COMPLEX, METHOD FOR PREPARING THIS COMPOUND, PREPARATION WITH ANTI-TUMOR EFFECT, CONTAINING AT LEAST A PLATINUM COMPOUND, AND FORMED PREPARATIONS WITH ANTI-TUMOR EFFECT.
CN102924528B (en) * 2012-10-29 2015-04-15 东南大学 Anti-tumor bivalent platinum complex and preparation method for complex and ligand of complex

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL189358C (en) * 1978-07-06 1993-03-16 Tno PROCESS FOR PREPARING A MEDICINE FOR THE TREATMENT OF CANCER, AND AN PLATINUM-DIAMMINE COMPLEX DERIVED FROM A 1,3-ALKANE DIAMINE.
NL7807334A (en) * 1978-07-06 1980-01-08 Tno PLATINUM DIAMINE COMPLEXES, METHOD FOR PREPARING THE SAME, METHOD FOR PREPARING A MEDICINAL PRODUCT USING SUCH A PLATINUM DIAMOND COMPLEX FOR THE TREATMENT OF CANCER, SO PREVENTLY DRIVED.
AU538863B2 (en) * 1980-05-27 1984-08-30 Bristol-Myers Company Platinum complex salts have anti-tumor property
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes

Also Published As

Publication number Publication date
DD217522A5 (en) 1985-01-16
DK483083A (en) 1984-04-22
IE56124B1 (en) 1991-04-24
GB8328084D0 (en) 1983-11-23
NO171276C (en) 1993-02-17
KR840006492A (en) 1984-11-30
JPS5993091A (en) 1984-05-29
YU210783A (en) 1986-08-31
DK75592A (en) 1992-06-09
IT8323359A0 (en) 1983-10-19
GB2128615B (en) 1986-07-16
JPH0244479B2 (en) 1990-10-04
FR2534907A1 (en) 1984-04-27
CS242888B2 (en) 1986-05-15
AT390610B (en) 1990-06-11
BE898058A (en) 1984-04-24
DK483083D0 (en) 1983-10-20
ATA373083A (en) 1989-11-15
ES526670A0 (en) 1984-07-01
FR2534907B1 (en) 1988-08-19
KR910002536B1 (en) 1991-04-23
FI833842A0 (en) 1983-10-20
CA1229618A (en) 1987-11-24
FI76351B (en) 1988-06-30
GR79652B (en) 1984-10-31
AU2027583A (en) 1984-05-03
FI833842A (en) 1984-04-22
NZ206018A (en) 1986-02-21
HU188035B (en) 1986-03-28
NL8204067A (en) 1984-05-16
CS775283A2 (en) 1985-08-15
NO833825L (en) 1984-04-24
YU43554B (en) 1989-08-31
FI76351C (en) 1988-10-10
AU562964B2 (en) 1987-06-25
LU85054A1 (en) 1984-03-22
DE3337333A1 (en) 1984-04-26
PH24077A (en) 1990-03-05
PT77542B (en) 1986-02-12
IT1169858B (en) 1987-06-03
PT77542A (en) 1983-11-01
CH658244A5 (en) 1986-10-31
SE8305783L (en) 1984-04-22
ES8406498A1 (en) 1984-07-01
IE832459L (en) 1984-04-21
GB2128615A (en) 1984-05-02
DK75592D0 (en) 1992-06-09
SE8305783D0 (en) 1983-10-20
NO171276B (en) 1992-11-09

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