IT1169858B - Complessi platino-diamminici, procedtimento per la loro prreparazione,procedimento per la preparazione di una compossizione medica contenente tali complessi platino-diamminici per il trattamento del cancro,nonche' composizione cosi' realizzata - Google Patents

Complessi platino-diamminici, procedtimento per la loro prreparazione,procedimento per la preparazione di una compossizione medica contenente tali complessi platino-diamminici per il trattamento del cancro,nonche' composizione cosi' realizzata

Info

Publication number
IT1169858B
IT1169858B IT23359/83A IT2335983A IT1169858B IT 1169858 B IT1169858 B IT 1169858B IT 23359/83 A IT23359/83 A IT 23359/83A IT 2335983 A IT2335983 A IT 2335983A IT 1169858 B IT1169858 B IT 1169858B
Authority
IT
Italy
Prior art keywords
platinum
procedure
preparation
complexes
diaminic
Prior art date
Application number
IT23359/83A
Other languages
English (en)
Other versions
IT8323359A0 (it
Inventor
Francois Verbeek
Jan Berg
Eric Jan Bulten
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of IT8323359A0 publication Critical patent/IT8323359A0/it
Application granted granted Critical
Publication of IT1169858B publication Critical patent/IT1169858B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT23359/83A 1982-10-21 1983-10-19 Complessi platino-diamminici, procedtimento per la loro prreparazione,procedimento per la preparazione di una compossizione medica contenente tali complessi platino-diamminici per il trattamento del cancro,nonche' composizione cosi' realizzata IT1169858B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8204067A NL8204067A (nl) 1982-10-21 1982-10-21 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.

Publications (2)

Publication Number Publication Date
IT8323359A0 IT8323359A0 (it) 1983-10-19
IT1169858B true IT1169858B (it) 1987-06-03

Family

ID=19840444

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23359/83A IT1169858B (it) 1982-10-21 1983-10-19 Complessi platino-diamminici, procedtimento per la loro prreparazione,procedimento per la preparazione di una compossizione medica contenente tali complessi platino-diamminici per il trattamento del cancro,nonche' composizione cosi' realizzata

Country Status (28)

Country Link
JP (1) JPS5993091A (it)
KR (1) KR910002536B1 (it)
AT (1) AT390610B (it)
AU (1) AU562964B2 (it)
BE (1) BE898058A (it)
CA (1) CA1229618A (it)
CH (1) CH658244A5 (it)
CS (1) CS242888B2 (it)
DD (1) DD217522A5 (it)
DE (1) DE3337333A1 (it)
DK (2) DK483083A (it)
ES (1) ES526670A0 (it)
FI (1) FI76351C (it)
FR (1) FR2534907B1 (it)
GB (1) GB2128615B (it)
GR (1) GR79652B (it)
HU (1) HU188035B (it)
IE (1) IE56124B1 (it)
IT (1) IT1169858B (it)
LU (1) LU85054A1 (it)
NL (1) NL8204067A (it)
NO (1) NO171276C (it)
NZ (1) NZ206018A (it)
PH (1) PH24077A (it)
PT (1) PT77542B (it)
SE (1) SE8305783L (it)
YU (1) YU43554B (it)
ZA (1) ZA837857B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
DE3762972D1 (de) * 1986-10-03 1990-07-05 Asta Pharma Ag Diamin-platin (ii)-komplexverbindungen mit einem hydroxylierten 2-phenyl-indolring.
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
CN102924528B (zh) * 2012-10-29 2015-04-15 东南大学 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
NL189358C (nl) * 1978-07-06 1993-03-16 Tno Werkwijze voor het bereiden van een geneesmiddel voor de behandeling van kanker, alsmede een van een 1,3-alkaandiamine afgeleid platina-diamminecomplex.
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes
NZ197104A (en) * 1980-05-27 1984-05-31 Bristol Myers Co Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives

Also Published As

Publication number Publication date
KR910002536B1 (ko) 1991-04-23
AU2027583A (en) 1984-05-03
DK75592A (da) 1992-06-09
FI833842A0 (fi) 1983-10-20
PH24077A (en) 1990-03-05
JPS5993091A (ja) 1984-05-29
DK483083D0 (da) 1983-10-20
FR2534907B1 (fr) 1988-08-19
JPH0244479B2 (it) 1990-10-04
LU85054A1 (it) 1984-03-22
FI76351C (fi) 1988-10-10
SE8305783L (sv) 1984-04-22
CS242888B2 (en) 1986-05-15
ES8406498A1 (es) 1984-07-01
NZ206018A (en) 1986-02-21
KR840006492A (ko) 1984-11-30
HU188035B (en) 1986-03-28
FR2534907A1 (fr) 1984-04-27
IE832459L (en) 1984-04-21
PT77542A (en) 1983-11-01
ES526670A0 (es) 1984-07-01
YU43554B (en) 1989-08-31
GB8328084D0 (en) 1983-11-23
GR79652B (it) 1984-10-31
IE56124B1 (en) 1991-04-24
IT8323359A0 (it) 1983-10-19
GB2128615A (en) 1984-05-02
NO833825L (no) 1984-04-24
CS775283A2 (en) 1985-08-15
CH658244A5 (de) 1986-10-31
AU562964B2 (en) 1987-06-25
ATA373083A (de) 1989-11-15
PT77542B (en) 1986-02-12
DK483083A (da) 1984-04-22
AT390610B (de) 1990-06-11
DK75592D0 (da) 1992-06-09
CA1229618A (en) 1987-11-24
YU210783A (en) 1986-08-31
DD217522A5 (de) 1985-01-16
BE898058A (nl) 1984-04-24
NL8204067A (nl) 1984-05-16
DE3337333A1 (de) 1984-04-26
FI833842A (fi) 1984-04-22
ZA837857B (en) 1984-06-27
SE8305783D0 (sv) 1983-10-20
NO171276C (no) 1993-02-17
NO171276B (no) 1992-11-09
GB2128615B (en) 1986-07-16
FI76351B (fi) 1988-06-30

Similar Documents

Publication Publication Date Title
IT1169858B (it) Complessi platino-diamminici, procedtimento per la loro prreparazione,procedimento per la preparazione di una compossizione medica contenente tali complessi platino-diamminici per il trattamento del cancro,nonche' composizione cosi' realizzata
HK9986A (en) Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed
HUT51241A (en) Process for production of arilhydrasones and medical compositions containing them
IT8219947A0 (it) Complessi platino-diamminici eprocedimento per la loro preparazione nonche' formulazioni farmaceutiche antitumorali contenenti tali complessi.
BG94738A (bg) Използване на разтвор на йод за лечение на заболявания, свързани с йодна недостатъчност
FR2523986B1 (fr) Articles medicaux sterilisables par irradiation
ES467931A1 (es) Procedimiento para la obtencion de piridinil-aminoalquilete-res
IL57785A0 (en) New imidazoquinoxalines and their salts,process for their preparation,their use as medicaments and the pharmaceutical compositions containing them
IL79910A (en) 5,7-dihydro-6-(thi)oxopyrrolo(2,3-f)benzimidazole,-benzothiazole and-benzoxazoles,6-imines thereof,their preparation and pharmaceutical compositions containing them
JPS529087A (en) Blood-compatible high-polymeric materials for medical use
AU5992990A (en) 14,17alpha-etheno- and -ethanoestratrienes, processes for the preparation of these compounds, as well as their use for the production of medicinal agents
IL65493A0 (en) Phenethanolamine derivatives,their preparation and pharmaceutical compositions containing them
IT8122035A0 (it) Composti di germanio, procedimento per la loro prparazione, procedimento per la preparazione di un farmaco mediante tali composti di germanio per il trattamento del cancro, nonche' medicinale finito cosi' ottenuto.
SE7706061L (sv) 3,5,5-trimetylhexanoyl-ferrocen och forfarande for dess framstellning
JPS55105654A (en) Novel dehydropeptide compounds*their manufacture and their medical use
IT1223416B (it) Procedimento per la realizzazione di calzature del tipo ciabatta, nonche' ciabatta cosi' realizzata
IT8122036A0 (it) Composti di stagno, procedimento per la loro preparazione, procedimento per la preparazione di un farmaco per il trattamento del cancro mediante un tale composto di stagno, nonche' medicinale finito cosi' ottenuto.
HUT35519A (en) Process for producing of anelgetic medical preparatives
GB8908906D0 (en) Therapeutic compounds,compositions & uses thereof
NZ220539A (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions
ZA813621B (en) Tin compounds,a process for the preparation thereof,a process for the preparation of a medicine using such a tin compound for the treatment of cancer,as well as the shaped medicine thus formed and obtained
IT1150612B (it) Procedimento per la preparazione del 1',5,7-tridrossi-4'-metossiflavone-7-rutinoside (diosmina)
IT8219330A0 (it) Composto medicinale per il trattamento di malattie di cuore.
ES501835A0 (es) Procedimiento para la preparacion de una composicion para el tratamiento del cancer
ZA796513B (en) Substituted 2-phenylamino-imidazolines-(2),having particular therapeutic properties,process for their preparation,and pharmaceutical compositions containing them