KR910002475A - 수용성 감압성 피부 접착물 및 이의 용도 - Google Patents

수용성 감압성 피부 접착물 및 이의 용도 Download PDF

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KR910002475A
KR910002475A KR1019900011148A KR900011148A KR910002475A KR 910002475 A KR910002475 A KR 910002475A KR 1019900011148 A KR1019900011148 A KR 1019900011148A KR 900011148 A KR900011148 A KR 900011148A KR 910002475 A KR910002475 A KR 910002475A
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adhesive
salt
weight
amino group
carbon atoms
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KR1019900011148A
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KR0150001B1 (ko
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페테라이트 한스-울리히
로트 에르나
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헤틀러, 부크
룀 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31511—Of epoxy ether

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Adhesive Tapes (AREA)

Abstract

내용 없음

Description

수용성 감압성 피부 접착물 및 이의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (28)

  1. (i) 아미노 그룹-함유 모노에틸렌계 불포화 단량제 및 (ii)하나 이상의 아크릴산, 메틸아크릴산 또는 이의 혼합물의 알킬 에스테르에 상응하는 단량체 단위를 함유하는 비가교결합된 공중합체 염(여기서, 상당량의 아미노그룹-함유 단량체는 상기 공중합체염이 수용성인염 형태이다)를 함유하는 가요성 감압성 접착물.
  2. 제1항에 있어서, 공중합체 염이 약 30 내지 80중량％의 아미노 그룹-함유 단량체를 함유하는 접착물.
  3. 제1항에 있어서, 알킬 에스테르가 아크릴산, 메타크릴산 또는 이의 혼합물의 C4-14알킬 에스테르를 포함하는 접착물.
  4. 제1항에 있어서, 염 형태가 유기 카복실산 음이온의 염인 접착물.
  5. 제4항에 있어서, 유기 카복실산 음이온의 탄소수가 4이상인 접착물.
  6. 제5항에 있어서, 유기 카복실산 음이온의 탄소수가 8 내지 20인 접착물.
  7. 제1항에 있어서, 아미노 그룹-함유 단량체의 염 형태가 하기 일반식인 접착물.
    상기식에서, R은 수소원자 또는 C4-4알킬 그룹이고, A는 산소원자 또는 NH이며, Alk는 C1-10알킬렌이고, R'는 탄소수 22이하의 동일하거나 상이한 알킬, 아릴 또는 아르알킬(여기서, 최대의 2R' 그룹은 수소원자이다)이며, X는 산 음이온이다.
  8. 제7항에 있어서, A가 NH인 접착물.
  9. 제7항에 있어서, A가 산소인 접착물.
  10. 제7항에 있어서, Alk가 C2-8알킬렌 그룹인 접착물.
  11. 제7항에 있어서, X탄소수 4이상의 유기 카복실산 음이온인 접착물.
  12. 제7항에 있어서, X탄소수 8 내지 20의 유기 카복실산 음이온인 접착물.
  13. 제1항에 있어서, 아미노 그룹-함유 단량체의 염 형태가 4급 암모늄 염인 접물.
  14. 제1항에 있어서, 공중합체 염이 추가로 아크릴 아미드, 메타크릴아미드, 아크릴산 또는 메타크릴산의 하이드록시알킬 에스테르, 아크릴산 또는 메타크릴산의 폴리알킬렌, 클리콜 에스테르, 에틸렌, 비닐 아세테이트, 비닐프로피오네이트 및 비닐피롤리돈중에서 선택된 공중합성 공단량체를 20중량％ 미만의 양으로 포함하는 접착물,
  15. 제1항에 있어서, 공중합체 염의 분자량이 약 20,000 내지 250,000인 접착물.
  16. 제1항에 있어서, 가소제 2 내지 200중량％을 추가로 함유하는 접착물.
  17. 제1항에 있어서, 무수 공중합체 염을 기준으로 하여 물 약 1 내지 10중량％을 함유하는 접착물.
  18. 제1항에서 있어서, 아미노 그룹-함유 단량체의 50 내지 100％가 염 형태인 접착물.
  19. 제1항에서 있어서, 아미노 그룹-함유 단량체의 80 내지 100％가 염 형태인 접착물.
  20. 20 내지 90중량％의 물 및 10 내지 80중량％의 제1항의 접착물을 함유하는 수용액.
  21. 제20항에 있어서 점성이 약 10mPa·s내지 10Pa·s인 용액.
  22. 대상물 및 피부사이에 제1항의 감압성 접착물을 삽입하고 상기 대상물에 압력을 적용함을 특징으로 하여, 대상물을 피부에 접착시키는 방법.
  23. 제22항에 있어서, 대상물이 붕대, 피복 또는 석고인 방법.
  24. 제22항에 있어서, 대상물 또는 접착물이 국부 또는 전신용 액제학적 성분인 방법.
  25. 기질의 하나 이상의 표면상에 제1항의 접착물로 피복시킨 기질을 함유하는, 피부에 국부 적용을 위한 대상물.
  26. 제25항에 있어서, 기질이 직물, 필름 또는 테이프인 대상물.
  27. 제26항에 있어서, 기질이 직물, 필름 또는 테이프 라미네이트인 대상물.
  28. 제25항에 있어서, 기질 또는 접착물이 국부 또는 전신용 약제학적 성분을 함유하는 대상물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900011148A 1989-07-24 1990-07-23 수성가요성 감압성 접착물 및 이를 사용하여 제조한 물품 KR0150001B1 (ko)

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DE39243931 1989-07-24
DE19893924393 DE3924393A1 (de) 1989-07-24 1989-07-24 Wasserloeslicher druckempfindlicher hauthaftkleber, dessen verwendung und damit ausgeruestete mittel
DEP39243931 1989-07-24

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KR910002475A true KR910002475A (ko) 1991-02-25
KR0150001B1 KR0150001B1 (ko) 1998-10-01

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US (1) US5133970A (ko)
EP (1) EP0415055B1 (ko)
JP (1) JP3311344B2 (ko)
KR (1) KR0150001B1 (ko)
AT (1) ATE115615T1 (ko)
DD (1) DD296694A5 (ko)
DE (2) DE3924393A1 (ko)
DK (1) DK0415055T3 (ko)
HU (1) HUT54063A (ko)

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JPS59135212A (ja) * 1983-01-24 1984-08-03 Nitto Chem Ind Co Ltd カチオン性重合体の製造方法
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Publication number Publication date
JP3311344B2 (ja) 2002-08-05
HUT54063A (en) 1991-01-28
DE59007998D1 (de) 1995-01-26
JPH0366775A (ja) 1991-03-22
EP0415055A2 (de) 1991-03-06
EP0415055B1 (de) 1994-12-14
DK0415055T3 (da) 1995-02-20
DE3924393A1 (de) 1991-01-31
KR0150001B1 (ko) 1998-10-01
ATE115615T1 (de) 1994-12-15
HU904583D0 (en) 1990-12-28
EP0415055A3 (en) 1992-04-01
US5133970A (en) 1992-07-28
DD296694A5 (de) 1991-12-12

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