KR900018370A - 가교 결합된 글루코우즈 이소머라제 - Google Patents

가교 결합된 글루코우즈 이소머라제 Download PDF

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KR900018370A
KR900018370A KR1019890006309A KR890006309A KR900018370A KR 900018370 A KR900018370 A KR 900018370A KR 1019890006309 A KR1019890006309 A KR 1019890006309A KR 890006309 A KR890006309 A KR 890006309A KR 900018370 A KR900018370 A KR 900018370A
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South Korea
Prior art keywords
glucose
isomerase
glucose isomerase
crystalline
insoluble
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KR1019890006309A
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비주리 칼레비
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라이너 니틸뢰
쿨토르 리미티드
주하 쿠르키넨
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Publication of KR900018370A publication Critical patent/KR900018370A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

내용 없음

Description

가교 결합된 글루코우즈 이소머라제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (14)

  1. 결정형 가요성 글루코우즈 이소머라제가 가교결합에 의해 수불용성 형태로 전환됨을 특징으로 하는 결정형 글루코우즈 이소머라제.
  2. 제1항에 있어서, pH가 1 내지 10범위의 묽은산 및 알칼리용액중에서 불용성임을 특징으로 하는 글루코우즈 이소머라제.
  3. 제1항 또는 2항에 있어서, 글루코우즈, 과당 및 다른 당의 수용액중에서 불용성임을 특징으로 하는 글루코우즈 이소머라제.
  4. 제3항에 있어서, 결정체가 승온에서도 상기 당용액 중에서 불용성임을 특징으로 하는 글루코우즈 이소머라제.
  5. 제1항에 있어서, 천연 기질인 글루코우즈, 과당 및 크실로우즈의 농축액중에서도 이들당의 이성화 반응을 촉매함을 특징으로 하는 글루코우즈 이소머라제.
  6. 제1항 내지 5항중 어느 한 항에 있어서, 결정체를 구형, 시트형, 밴드형 또는 이들의 배합물형과 같은 대형체내에 화학적으로 또는 물리적으로 결합시킴을 특징으로 하는 글루코우즈 이소머라제.
  7. 수불용성이고, 실질적으로 순수한, 가교결합된 결정형 글루코우즈 이소머라제를 함유함을 특징으로 하는 과당의 연속제조에 유용한 반응장치.
  8. a) 암노늄염, 아민 또는 아미노산과 같은 적어도 하나이상의 아미노 그룹을 함유하는 화합물을 디알데하이드의 첨가전 또는 가교결합 반응동안에 결정형 이소머라제 현탁액중에 가한후, 디알데하이드를 결정형 이소머라제 현탁액중에서 가한 다음, b) 물 또는 다른 액체를 사용하여 가교결합된 결정체를 세척하여 시약잔사를 제거함을 특징으로 하여, 수불용성 가교결합된 결정형 효소를 제조하는 방법.
  9. 제8항에 있어서, 효소가 글루코우즈 이소머라제인 방법.
  10. 제8항에 있어서, 디알데하이드가 글루타르-알데하이드임을 특징으로 하는 방법.
  11. 제8항 또는 9항에 있어서, 글루타르알데하이드의 양이 0.4 내지 8중량%임을 특징으로 하는 방법.
  12. 가교결합된 결정형 이소머라제를 사용하여 기질을 이의 이성체로의 전환을 촉매하는 방법.
  13. 제12항에 있어서, 기질이 글루코우즈, 과당 또는 크실로우즈이고 이소머라제가 글루코우즈 이소머라제인 방법.
  14. 글루코우즈-함유 용액을 수불용성 가교결합된 결정형 글루코우즈 이소머라제를 함유하는 반응기에 통과시킴을 특징으로 하여 과당을 연속적으로 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890006309A 1988-05-13 1989-05-11 가교 결합된 글루코우즈 이소머라제 KR900018370A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI882249A FI85285C (fi) 1988-05-13 1988-05-13 Tvaerbundet, vattenoloesligt glukosisomeras och foerfarande foer framstaellning daerav.
FI882249 1988-05-13

Publications (1)

Publication Number Publication Date
KR900018370A true KR900018370A (ko) 1990-12-21

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Country Status (18)

Country Link
US (3) US5437993A (ko)
EP (1) EP0341503B1 (ko)
JP (1) JP2599789B2 (ko)
KR (1) KR900018370A (ko)
CN (1) CN1038123A (ko)
AT (1) ATE95232T1 (ko)
AU (1) AU3381689A (ko)
CA (1) CA1320463C (ko)
DD (1) DD297843A5 (ko)
DE (1) DE68909488T2 (ko)
DK (1) DK169039B1 (ko)
ES (1) ES2059610T3 (ko)
FI (1) FI85285C (ko)
HU (1) HU206134B (ko)
IE (1) IE63128B1 (ko)
IN (1) IN169420B (ko)
NO (1) NO891943L (ko)
ZA (1) ZA893460B (ko)

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US5618710A (en) * 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
US5801022A (en) * 1990-08-03 1998-09-01 Vertex Pharmaceuticals, Incorporated Method of producing a product with crosslinked crystals of thermolysin
ATE323158T1 (de) * 1990-08-03 2006-04-15 Vertex Pharma Verwendung von vernetzten kristallen als neue form von immobilisierung von enzymen
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AU6029998A (en) * 1997-01-17 1998-08-07 Regents Of The University Of Minnesota Dna molecules and protein displaying improved triazine compound degrading ability
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6500933B1 (en) 1997-09-05 2002-12-31 Altus Biologics Inc. Methods of preparing carbohydrate crosslinked glycoprotein crystals
DK1009759T3 (da) * 1997-09-05 2008-08-04 Altus Pharmaceuticals Inc Carbohydrat-tværbundne glycoproteinkrystaller
AU2001231155A1 (en) 2000-01-25 2001-08-07 Hugh Mctavish Microbes and methods for remediation
US8835143B2 (en) 2004-10-28 2014-09-16 Clea Technologies Bv Method for preparing hybrid cross-linked enzyme-silica aggregates
NL1027360C2 (nl) * 2004-10-28 2006-05-01 Clea Technologies B V Werkwijze voor de bereiding van vernette enzymaggregaten met verbeterde eigenschappen.
EP3269383A1 (de) * 2008-09-04 2018-01-17 Stada Arzneimittel Ag Behandlung von fruktose-malabsorption
AU2011272825A1 (en) 2010-06-30 2013-01-10 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US9745666B2 (en) * 2012-09-10 2017-08-29 Gtat Ip Holding Llc Continuous czochralski method and apparatus
US20140144371A1 (en) * 2012-11-29 2014-05-29 Solaicx, Inc. Heat Shield For Improved Continuous Czochralski Process
CN103849927A (zh) * 2012-11-30 2014-06-11 有研半导体材料股份有限公司 一种直拉法生长低电阻率单晶硅用掺杂装置及掺杂方法
GB201409451D0 (en) 2014-05-28 2014-07-09 Ipabc Ltd Antimicrobial preparations, methods for preparing the same and uses thereof to combat microorganisms
CN105063747A (zh) * 2015-07-21 2015-11-18 李剑 一种液态连续加料多晶硅铸锭设备及其生产方法
CN106012010A (zh) * 2016-08-15 2016-10-12 江苏协鑫硅材料科技发展有限公司 一种二次添加掺杂剂的方法和装置
CN108301038A (zh) * 2017-01-12 2018-07-20 新疆知信科技有限公司 一种单晶硅提拉炉和生长单晶硅的拉制方法
CN114729346A (zh) 2019-09-13 2022-07-08 丹尼斯科美国公司 热稳定的葡萄糖异构酶变体
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Also Published As

Publication number Publication date
EP0341503A3 (en) 1990-06-13
FI85285B (fi) 1991-12-13
DD297843A5 (de) 1992-01-23
ES2059610T3 (es) 1994-11-16
JPH02291265A (ja) 1990-12-03
DE68909488T2 (de) 1994-01-20
AU3381689A (en) 1989-11-16
IE63128B1 (en) 1995-03-22
US5437993A (en) 1995-08-01
FI85285C (fi) 1992-03-25
NO891943L (no) 1989-11-14
DE68909488D1 (de) 1993-11-04
ATE95232T1 (de) 1993-10-15
US5900364A (en) 1999-05-04
IN169420B (ko) 1991-10-12
HU206134B (en) 1992-08-28
DK231989A (da) 1989-11-14
EP0341503B1 (en) 1993-09-29
IE891435L (en) 1989-11-13
EP0341503A2 (en) 1989-11-15
FI882249A0 (fi) 1988-05-13
CN1038123A (zh) 1989-12-20
JP2599789B2 (ja) 1997-04-16
ZA893460B (en) 1990-01-31
NO891943D0 (no) 1989-05-12
DK169039B1 (da) 1994-08-01
FI882249A (fi) 1989-11-14
DK231989D0 (da) 1989-05-12
CA1320463C (en) 1993-07-20
US5811280A (en) 1998-09-22

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