KR880001077B1 - 4-페닐 퀴나졸린 유도체의 제조방법 - Google Patents

4-페닐 퀴나졸린 유도체의 제조방법 Download PDF

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Publication number
KR880001077B1
KR880001077B1 KR8204715A KR820004715A KR880001077B1 KR 880001077 B1 KR880001077 B1 KR 880001077B1 KR 8204715 A KR8204715 A KR 8204715A KR 820004715 A KR820004715 A KR 820004715A KR 880001077 B1 KR880001077 B1 KR 880001077B1
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KR
South Korea
Prior art keywords
phenyl
phosphorus
solvent
group
phenyl quinazoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8204715A
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English (en)
Korean (ko)
Other versions
KR840001968A (ko
Inventor
알로 앙드레
비지에르 까스린
Original Assignee
쟝루이 드라뤼
소시에떼아노님 사노피
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 쟝루이 드라뤼, 소시에떼아노님 사노피 filed Critical 쟝루이 드라뤼
Publication of KR840001968A publication Critical patent/KR840001968A/ko
Application granted granted Critical
Publication of KR880001077B1 publication Critical patent/KR880001077B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
KR8204715A 1981-10-21 1982-10-20 4-페닐 퀴나졸린 유도체의 제조방법 Expired KR880001077B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8119767A FR2514765A1 (fr) 1981-10-21 1981-10-21 Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
FR81/19767 1981-10-21

Publications (2)

Publication Number Publication Date
KR840001968A KR840001968A (ko) 1984-06-07
KR880001077B1 true KR880001077B1 (ko) 1988-06-22

Family

ID=9263248

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8204715A Expired KR880001077B1 (ko) 1981-10-21 1982-10-20 4-페닐 퀴나졸린 유도체의 제조방법

Country Status (24)

Country Link
US (1) US4499092A (enExample)
EP (1) EP0079810B1 (enExample)
JP (1) JPS5888369A (enExample)
KR (1) KR880001077B1 (enExample)
AT (1) ATE17576T1 (enExample)
AU (1) AU551938B2 (enExample)
CA (1) CA1236102A (enExample)
CS (1) CS229692B2 (enExample)
DD (1) DD210040A5 (enExample)
DE (1) DE3268699D1 (enExample)
DK (1) DK156063C (enExample)
ES (1) ES516694A0 (enExample)
FI (1) FI73982C (enExample)
FR (1) FR2514765A1 (enExample)
GR (1) GR76535B (enExample)
HU (1) HU187579B (enExample)
IE (1) IE53653B1 (enExample)
IL (1) IL66960A0 (enExample)
NO (1) NO164167C (enExample)
NZ (1) NZ202237A (enExample)
PT (1) PT75667B (enExample)
SU (1) SU1299511A3 (enExample)
YU (1) YU43528B (enExample)
ZA (1) ZA827516B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
US5646154A (en) * 1992-10-07 1997-07-08 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical compositions for inhibiting the formation of tumor necrosis factor
JPH11209350A (ja) 1998-01-26 1999-08-03 Eisai Co Ltd 含窒素複素環誘導体およびその医薬
EP1618094B1 (en) * 2003-04-30 2007-09-05 The Institutes for Pharmaceutical Discovery, LLC Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
JP2007510642A (ja) * 2003-11-03 2007-04-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 中枢神経系障害の治療のための新規ノルエピネフリン再取込み阻害薬
BRPI0614032A2 (pt) 2005-06-27 2011-03-01 Hoffmann La Roche guanidinas substituìdas com cloro
US7855194B2 (en) 2006-03-27 2010-12-21 Hoffmann-La Roche Inc. Pyrimidine, quinazoline, pteridine and triazine derivatives
BRPI0719111A8 (pt) * 2006-11-22 2019-01-15 Sumitomo Chemical Co agente para inibir a sinalização de citocinina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA894239A (en) * 1972-02-29 Pfizer Inc. Nitrogen heterocycles
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
JPS5398997A (en) * 1977-02-09 1978-08-29 Sumitomo Chem Co Ltd Fused pyridine derivertives and process for their preparation

Also Published As

Publication number Publication date
HU187579B (en) 1986-01-28
ATE17576T1 (de) 1986-02-15
ES8307226A1 (es) 1983-07-01
CS229692B2 (en) 1984-06-18
SU1299511A3 (ru) 1987-03-23
NZ202237A (en) 1985-08-30
ES516694A0 (es) 1983-07-01
US4499092A (en) 1985-02-12
DK465182A (da) 1983-04-22
DE3268699D1 (en) 1986-03-06
YU223382A (en) 1984-10-31
EP0079810B1 (fr) 1986-01-22
KR840001968A (ko) 1984-06-07
FI823580A0 (fi) 1982-10-20
PT75667B (fr) 1985-01-11
EP0079810A1 (fr) 1983-05-25
AU8962882A (en) 1983-04-28
DK156063B (da) 1989-06-19
NO164167C (no) 1990-09-05
CA1236102A (en) 1988-05-03
IL66960A0 (en) 1983-02-23
IE822447L (en) 1983-04-21
FI823580L (fi) 1983-04-22
DD210040A5 (de) 1984-05-30
GR76535B (enExample) 1984-08-10
FI73982B (fi) 1987-08-31
NO164167B (no) 1990-05-28
YU43528B (en) 1989-08-31
FR2514765A1 (fr) 1983-04-22
NO823491L (no) 1983-04-22
JPS5888369A (ja) 1983-05-26
IE53653B1 (en) 1989-01-04
PT75667A (fr) 1982-11-01
FI73982C (fi) 1987-12-10
FR2514765B1 (enExample) 1984-04-06
DK156063C (da) 1989-11-13
AU551938B2 (en) 1986-05-15
ZA827516B (en) 1983-08-31

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