KR870005640A - 항진균성 손톱와니스의 제조방법 - Google Patents
항진균성 손톱와니스의 제조방법 Download PDFInfo
- Publication number
- KR870005640A KR870005640A KR860010941A KR860010941A KR870005640A KR 870005640 A KR870005640 A KR 870005640A KR 860010941 A KR860010941 A KR 860010941A KR 860010941 A KR860010941 A KR 860010941A KR 870005640 A KR870005640 A KR 870005640A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- weight
- amount
- nail varnish
- nail
- Prior art date
Links
- 239000002966 varnish Substances 0.000 title claims 8
- 238000004519 manufacturing process Methods 0.000 title claims 6
- 230000000843 anti-fungal effect Effects 0.000 title claims 3
- 229940121375 antifungal agent Drugs 0.000 title claims 3
- 150000001875 compounds Chemical class 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 210000003298 dental enamel Anatomy 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- SNUSZUYTMHKCPM-UHFFFAOYSA-N 1-hydroxypyridin-2-one Chemical compound ON1C=CC=CC1=O SNUSZUYTMHKCPM-UHFFFAOYSA-N 0.000 claims 1
- 241001480043 Arthrodermataceae Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 230000037304 dermatophytes Effects 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 150000003839 salts Chemical group 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
Abstract
Description
Claims (10)
- 수-불용성 필름-형성물질을 일반식(I)의 항진균성 화합물 및, 임의로 또한 손톱와니스 제조시에 일반적으로 사용되는 다른 성분들과 함께 혼합함을 특징으로 하여,수-불용성 필름-형성 물질 및, 유리형태 또는 염의 형태로 존재하는 하기 일반식(I)의 1-하이드록시 -2-피리돈인 항 진균성 화합물로 이루어지는 손톱와니스를 제조하는 방법.상기식에서R'은 6 내지 9개의 탄소원자를 함유하고,올레핀성 및 아세틸렌성 결함을 함유하지 않는 탄화수소 그룹이고;R2및 R4그룹중의 하나는 수소이고 다른 하나는 수소, 메틸 또는 에틸이며;R3는 두개까지의 탄소원자를 함유하는 알킬이다.
- 제1항에 있어서, 일반식(I)의 화합물에서 R2및 R4가 수소인 방법.
- 제1 또는 2항에 있어서, 화합물(I)에서의 R1이 사이클릭 그룹을 함유하는 방법.
- 제3항에 있어서, 사이클릭그룹이 사이클로헥실 그룹이고, R1바람직하게는 사이클로헥실 그룹인 방법.
- 제 1 또는 2항에 있어서, 화합물(I)에서의 R1이 바람직하게는구조식-CH2-CH(CH3)-CH2-C(CH3)3의 옥틸 그룹인 방법.
- 제1 내지 5항중 어느 한 항에 있어서, 조진균증을 일으미는 피부사상균을 사멸시키는데에 유효한 양의 화합물(I)을 함유하는 의약용 손톱에나멜인 손톱와니스를 제조하는 방법.
- 제1 내지 6항중 어느 한 항에 있어서, 비-휘발성 성분의 양을 기준으로 하여 화합물(I)을 2 내지 80중량%, 바람직하게는 10 내지 60 중량%, 특히 20 내지 40중량%의 양으로 함유하는 손톱와니스를 제조하는 방법.
- 제1 내지 7항중 어느 한 항에 있어서, 화합물(I)을 0.5 내지 20중량%, 바람직하게는 2 내지 15중량%의 양으로 함유하는 손톱와니스를 제조하는 방법.
- 제8항에 있어서, 적어도 4중량%의 양으로 화합물(I)을 함유하는 의약용 손톱 에나멜인 손톱와니스를 제조하는 방법.
- 제8항에 잇어서, 화합물(I)을 4중량%미만, 바람직하게는 적어도 1중량%의 양으로 함유하는 손톱와니스를 제조하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853544983 DE3544983A1 (de) | 1985-12-19 | 1985-12-19 | Antimykotisch wirksamer nagellack |
DEP3544983.7 | 1985-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870005640A true KR870005640A (ko) | 1987-07-06 |
KR940002942B1 KR940002942B1 (en) | 1994-04-09 |
Family
ID=6288889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR8610941A KR940002942B1 (en) | 1985-12-19 | 1986-12-19 | Process for preparing antimycotic nail varnish |
Country Status (25)
Country | Link |
---|---|
US (1) | US4957730A (ko) |
EP (1) | EP0226984B1 (ko) |
JP (1) | JPS62155205A (ko) |
KR (1) | KR940002942B1 (ko) |
AT (1) | ATE53292T1 (ko) |
AU (1) | AU587883B2 (ko) |
CA (1) | CA1283054C (ko) |
DD (1) | DD284598A5 (ko) |
DE (2) | DE3544983A1 (ko) |
DK (1) | DK175104B1 (ko) |
ES (1) | ES2016247B3 (ko) |
FI (1) | FI865147A (ko) |
GR (1) | GR3000641T3 (ko) |
HK (1) | HK81892A (ko) |
HU (1) | HU200908B (ko) |
IE (1) | IE59318B1 (ko) |
IL (1) | IL81021A (ko) |
MA (1) | MA20834A1 (ko) |
MY (1) | MY100300A (ko) |
NO (1) | NO173364C (ko) |
PH (1) | PH22283A (ko) |
PT (1) | PT83964B (ko) |
SG (1) | SG79692G (ko) |
TN (1) | TNSN86163A1 (ko) |
ZA (1) | ZA869497B (ko) |
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1985
- 1985-12-19 DE DE19853544983 patent/DE3544983A1/de not_active Withdrawn
-
1986
- 1986-12-13 ES ES86117377T patent/ES2016247B3/es not_active Expired - Lifetime
- 1986-12-13 AT AT86117377T patent/ATE53292T1/de not_active IP Right Cessation
- 1986-12-13 DE DE3671699T patent/DE3671699C5/de not_active Expired - Lifetime
- 1986-12-13 EP EP86117377A patent/EP0226984B1/de not_active Expired - Lifetime
- 1986-12-17 PH PH34605A patent/PH22283A/en unknown
- 1986-12-17 FI FI865147A patent/FI865147A/fi not_active Application Discontinuation
- 1986-12-17 HU HU865267A patent/HU200908B/hu unknown
- 1986-12-17 MA MA21066A patent/MA20834A1/fr unknown
- 1986-12-17 US US06/942,699 patent/US4957730A/en not_active Expired - Lifetime
- 1986-12-18 DD DD86297908A patent/DD284598A5/de not_active IP Right Cessation
- 1986-12-18 TN TNTNSN86163A patent/TNSN86163A1/fr unknown
- 1986-12-18 MY MYPI86000222A patent/MY100300A/en unknown
- 1986-12-18 PT PT83964A patent/PT83964B/pt unknown
- 1986-12-18 IL IL81021A patent/IL81021A/xx not_active IP Right Cessation
- 1986-12-18 CA CA000525793A patent/CA1283054C/en not_active Expired - Lifetime
- 1986-12-18 JP JP61300239A patent/JPS62155205A/ja active Granted
- 1986-12-18 IE IE331286A patent/IE59318B1/en not_active IP Right Cessation
- 1986-12-18 ZA ZA869497A patent/ZA869497B/xx unknown
- 1986-12-18 AU AU66707/86A patent/AU587883B2/en not_active Expired
- 1986-12-18 NO NO865158A patent/NO173364C/no not_active IP Right Cessation
- 1986-12-18 DK DK198606136A patent/DK175104B1/da not_active IP Right Cessation
- 1986-12-19 KR KR8610941A patent/KR940002942B1/ko not_active IP Right Cessation
-
1990
- 1990-07-12 GR GR90400432T patent/GR3000641T3/el unknown
-
1992
- 1992-08-07 SG SG796/92A patent/SG79692G/en unknown
- 1992-10-22 HK HK818/92A patent/HK81892A/xx not_active IP Right Cessation
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