KR870001267B1 - 5-(2-알콕시페닐)티아졸 리딘디온의 제조방법 - Google Patents

5-(2-알콕시페닐)티아졸 리딘디온의 제조방법 Download PDF

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Publication number
KR870001267B1
KR870001267B1 KR1019840000150A KR840000150A KR870001267B1 KR 870001267 B1 KR870001267 B1 KR 870001267B1 KR 1019840000150 A KR1019840000150 A KR 1019840000150A KR 840000150 A KR840000150 A KR 840000150A KR 870001267 B1 KR870001267 B1 KR 870001267B1
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KR
South Korea
Prior art keywords
chloro
methyl
alkoxyphenyl
alpha
hydrogen
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Expired
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KR1019840000150A
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English (en)
Korean (ko)
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KR840007223A (ko
Inventor
커렌 쉬너 로드니
Original Assignee
화이자 인코포레이티드
윌리암 데이비스 헌
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Publication of KR840007223A publication Critical patent/KR840007223A/ko
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Publication of KR870001267B1 publication Critical patent/KR870001267B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Paints Or Removers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1019840000150A 1983-01-17 1984-01-16 5-(2-알콕시페닐)티아졸 리딘디온의 제조방법 Expired KR870001267B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45868483A 1983-01-17 1983-01-17
US458,684 1983-01-17
US458684 1983-01-17

Publications (2)

Publication Number Publication Date
KR840007223A KR840007223A (ko) 1984-12-06
KR870001267B1 true KR870001267B1 (ko) 1987-06-30

Family

ID=23821708

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840000150A Expired KR870001267B1 (ko) 1983-01-17 1984-01-16 5-(2-알콕시페닐)티아졸 리딘디온의 제조방법

Country Status (26)

Country Link
EP (1) EP0117035B1 (enExample)
JP (1) JPS59137474A (enExample)
KR (1) KR870001267B1 (enExample)
AT (1) ATE45574T1 (enExample)
AU (1) AU539921B2 (enExample)
CA (1) CA1233470A (enExample)
CS (1) CS241149B2 (enExample)
DD (1) DD216012A5 (enExample)
DE (1) DE3479419D1 (enExample)
DK (1) DK17984A (enExample)
EG (1) EG16563A (enExample)
ES (1) ES8506663A1 (enExample)
FI (1) FI840155L (enExample)
GR (1) GR79763B (enExample)
GT (1) GT198400006A (enExample)
HU (1) HU191265B (enExample)
IE (1) IE56842B1 (enExample)
IL (1) IL70690A (enExample)
NO (1) NO162462C (enExample)
NZ (1) NZ206845A (enExample)
PH (1) PH18882A (enExample)
PL (1) PL142152B1 (enExample)
PT (1) PT77958B (enExample)
SU (1) SU1189341A3 (enExample)
YU (1) YU43336B (enExample)
ZA (1) ZA84305B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210339B (en) 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
GB8910639D0 (en) * 1989-05-09 1989-06-21 Beecham Group Plc Novel compounds
JPH04210683A (ja) * 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
JP3053490B2 (ja) * 1991-02-25 2000-06-19 杏林製薬株式会社 チアゾリジン−２，４−ジオン誘導体とその塩及び製造法
JP2020509047A (ja) * 2017-03-03 2020-03-26 ギリアード サイエンシーズ， インコーポレイテッド Ａｃｃ阻害剤およびその固体形態を調製するためのプロセス

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2263296A1 (de) * 1972-12-23 1974-06-27 Bayer Ag 4-alkyl-thiazol-2-one, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AU6610081A (en) * 1980-01-24 1981-07-30 Senju Pharmaceutical Co., Ltd. Thiazolidine derivatives
JPS56104876A (en) * 1980-01-24 1981-08-20 Takeda Chem Ind Ltd Thiazolidine derivative
JPS5728075A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Thiazolidine derivative
JPS5728073A (en) * 1980-07-29 1982-02-15 Takeda Chem Ind Ltd Inhibitor for aldose reducing enzyme
JPS57123175A (en) * 1981-01-26 1982-07-31 Takeda Chem Ind Ltd Preparation of thiazolidine derivative

Also Published As

Publication number Publication date
JPH0329073B2 (enExample) 1991-04-23
DD216012A5 (de) 1984-11-28
PT77958B (en) 1986-06-18
IE56842B1 (en) 1992-01-01
PT77958A (en) 1984-02-01
PH18882A (en) 1985-10-22
EP0117035A3 (en) 1987-01-14
ATE45574T1 (de) 1989-09-15
CA1233470A (en) 1988-03-01
YU6184A (en) 1986-06-30
HU191265B (en) 1987-01-28
JPS59137474A (ja) 1984-08-07
ZA84305B (en) 1985-08-28
DK17984D0 (da) 1984-01-16
CS38584A2 (en) 1985-07-16
CS241149B2 (en) 1986-03-13
NO162462B (no) 1989-09-25
AU2328784A (en) 1984-07-19
NO162462C (no) 1990-01-03
FI840155A7 (fi) 1984-07-18
YU43336B (en) 1989-06-30
NZ206845A (en) 1986-09-10
PL142152B1 (en) 1987-09-30
GT198400006A (es) 1985-07-06
KR840007223A (ko) 1984-12-06
FI840155A0 (fi) 1984-01-16
FI840155L (fi) 1984-07-18
DK17984A (da) 1984-07-18
EP0117035B1 (en) 1989-08-16
EG16563A (en) 1989-06-30
ES528887A0 (es) 1985-08-01
SU1189341A3 (ru) 1985-10-30
NO840144L (no) 1984-07-18
PL245745A1 (en) 1984-10-22
IL70690A0 (en) 1984-04-30
DE3479419D1 (en) 1989-09-21
IL70690A (en) 1989-01-31
AU539921B2 (en) 1984-10-25
ES8506663A1 (es) 1985-08-01
IE840079L (en) 1984-07-17
GR79763B (enExample) 1984-10-31
EP0117035A2 (en) 1984-08-29

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