KR870000183B1 - 페닐알킬아민의 제조방법 - Google Patents

페닐알킬아민의 제조방법 Download PDF

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Publication number
KR870000183B1
KR870000183B1 KR1019810004912A KR810004912A KR870000183B1 KR 870000183 B1 KR870000183 B1 KR 870000183B1 KR 1019810004912 A KR1019810004912 A KR 1019810004912A KR 810004912 A KR810004912 A KR 810004912A KR 870000183 B1 KR870000183 B1 KR 870000183B1
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KR
South Korea
Prior art keywords
group
carbon atoms
phenyl
amino
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019810004912A
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English (en)
Korean (ko)
Other versions
KR830007505A (ko
Inventor
켁 요하네스
피이퍼 헬무트
크뤼거 게르트
놀 클라우스
댐겐 위르겐
카다쯔 루돌프
디이데렌 빌리
Original Assignee
닥 칼토매 게젤샤프트 미트 베슈랭크터 하프퉁
하인쯔 쉐플러, 프리쯔 좀머
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 닥 칼토매 게젤샤프트 미트 베슈랭크터 하프퉁, 하인쯔 쉐플러, 프리쯔 좀머 filed Critical 닥 칼토매 게젤샤프트 미트 베슈랭크터 하프퉁
Publication of KR830007505A publication Critical patent/KR830007505A/ko
Application granted granted Critical
Publication of KR870000183B1 publication Critical patent/KR870000183B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B23/00—Record carriers not specific to the method of recording or reproducing; Accessories, e.g. containers, specially adapted for co-operation with the recording or reproducing apparatus ; Intermediate mediums; Apparatus or processes specially adapted for their manufacture
    • G11B23/02—Containers; Storing means both adapted to cooperate with the recording or reproducing means
    • G11B23/04—Magazines; Cassettes for webs or filaments
    • G11B23/08—Magazines; Cassettes for webs or filaments for housing webs or filaments having two distinct ends
    • G11B23/087—Magazines; Cassettes for webs or filaments for housing webs or filaments having two distinct ends using two different reels or cores
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B25/00—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus
    • G11B25/06—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus using web-form record carriers, e.g. tape
    • G11B25/066—Apparatus characterised by the shape of record carrier employed but not specific to the method of recording or reproducing, e.g. dictating apparatus; Combinations of such apparatus using web-form record carriers, e.g. tape adapted for use with containers of different sizes or configurations; adaptor devices therefor

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
KR1019810004912A 1980-12-10 1981-12-10 페닐알킬아민의 제조방법 Expired KR870000183B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3046465 1980-12-10
DE3046465.4 1980-12-10

Publications (2)

Publication Number Publication Date
KR830007505A KR830007505A (ko) 1983-10-21
KR870000183B1 true KR870000183B1 (ko) 1987-02-14

Family

ID=6118763

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810004912A Expired KR870000183B1 (ko) 1980-12-10 1981-12-10 페닐알킬아민의 제조방법

Country Status (32)

Country Link
JP (1) JPS57122048A (enrdf_load_stackoverflow)
KR (1) KR870000183B1 (enrdf_load_stackoverflow)
AR (1) AR227802A1 (enrdf_load_stackoverflow)
AT (1) AT379378B (enrdf_load_stackoverflow)
AU (1) AU547655B2 (enrdf_load_stackoverflow)
BE (1) BE891416A (enrdf_load_stackoverflow)
CA (1) CA1202636A (enrdf_load_stackoverflow)
CH (1) CH651541A5 (enrdf_load_stackoverflow)
CS (1) CS229924B2 (enrdf_load_stackoverflow)
DD (1) DD202867A5 (enrdf_load_stackoverflow)
DE (1) DE3146623A1 (enrdf_load_stackoverflow)
DK (1) DK541981A (enrdf_load_stackoverflow)
ES (4) ES507635A0 (enrdf_load_stackoverflow)
FI (1) FI813934A7 (enrdf_load_stackoverflow)
FR (1) FR2498596B1 (enrdf_load_stackoverflow)
GB (1) GB2088873B (enrdf_load_stackoverflow)
GR (1) GR77323B (enrdf_load_stackoverflow)
HU (1) HU185676B (enrdf_load_stackoverflow)
IE (1) IE52007B1 (enrdf_load_stackoverflow)
IL (1) IL64498A (enrdf_load_stackoverflow)
IT (1) IT1172129B (enrdf_load_stackoverflow)
LU (1) LU83830A1 (enrdf_load_stackoverflow)
NL (1) NL8105170A (enrdf_load_stackoverflow)
NO (1) NO152649C (enrdf_load_stackoverflow)
NZ (1) NZ199215A (enrdf_load_stackoverflow)
PH (1) PH21599A (enrdf_load_stackoverflow)
PL (1) PL129385B1 (enrdf_load_stackoverflow)
PT (1) PT74112B (enrdf_load_stackoverflow)
SE (1) SE8107387L (enrdf_load_stackoverflow)
SU (1) SU1172449A3 (enrdf_load_stackoverflow)
YU (1) YU290381A (enrdf_load_stackoverflow)
ZA (1) ZA818529B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720586A (en) * 1983-12-06 1988-01-19 Fisons, Plc Substituted 3,4-dihydroxy-phenylethylamino compounds
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
GB8426191D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
EP0278727A3 (en) * 1987-02-10 1990-03-14 Glaxo Group Limited 1-(4-amino-3-chloro-5-trifluoromethylphenyl)-2-(substituted amino)ethanol derivatives and their use in the treatment of respiratory disease
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
US4906645A (en) * 1988-09-12 1990-03-06 Merck & Co., Inc. Pyridyl aminoethanol compounds with growth promotion and an increase in feed efficiency
DE4028398A1 (de) * 1990-09-07 1992-03-12 Thomae Gmbh Dr K Phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
KR100187952B1 (ko) * 1991-10-04 1999-06-01 우에하라 아끼라 알콕시페닐알킬아민 유도체
US8349898B2 (en) * 2008-11-18 2013-01-08 Wisconsin Alumni Research Foundation Sigma-1 receptor ligands and methods of use
GB201208775D0 (en) * 2012-05-18 2012-07-04 Uni I Oslo Chemical compounds
US10668030B2 (en) * 2016-04-21 2020-06-02 University Of Kentucky Research Foundation Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse
US11999676B2 (en) 2016-04-21 2024-06-04 University Of Kentucky Research Foundation Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse
CN119255852A (zh) * 2022-05-31 2025-01-03 科迪华农业科技有限责任公司 吡啶酰胺杀真菌剂化合物的结晶形式

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618007A1 (de) * 1967-05-09 1970-10-29 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-monohalogenphenylaethanolaminen
DE2351281C3 (de) * 1973-10-12 1981-07-30 Dr. Karl Thomae Gmbh, 7950 Biberach Aminophenyl-äthanolamin-Derivate, deren Herstellung und Verwendung
NL176168C (nl) * 1972-12-18 1985-03-01 Thomae Gmbh Dr K Werkwijze ter bereiding respectievelijk vervaardiging van een farmaceutisch preparaat en werkwijze ter bereiding van daarbij bruikbare nieuwe gesubstitueerde 1-(4-aminofenyl)-2-amino-ethanol-derivaten die, behalve een analgetische, uterusspasmolytische en anti-spastische werking op de dwarsgestreepte spieren, in het bijzonder een betaŸ2-mimetische en/of betaŸ1-blokkerende werking bezitten.
GB1523974A (en) * 1975-02-05 1978-09-06 Yamanouchi Pharma Co Ltd 4-substituted amino- -aminomethylbenzyl alcohol derivatives
JPS51125232A (en) * 1975-02-05 1976-11-01 Yamanouchi Pharmaceut Co Ltd Process for preparing 4-substituted amido-3,5-dihalogeno-alpha-substituted aminomethylbenzyl alcohols
EP0006961A1 (en) * 1978-02-21 1980-01-23 Sandoz Ag New phenylethylamines, process for their preparation, and pharmaceutical compositions containing them
DK268579A (da) * 1978-07-03 1980-01-04 Lilly Co Eli Fremgangsmaade til fremstilling af phenetamolaminer

Also Published As

Publication number Publication date
ES8301890A1 (es) 1983-01-01
AU7841481A (en) 1982-09-23
PL234155A1 (enrdf_load_stackoverflow) 1982-08-02
IE52007B1 (en) 1987-05-13
IL64498A0 (en) 1982-03-31
NO814194L (no) 1982-06-11
ATA512981A (de) 1985-05-15
JPS57122048A (en) 1982-07-29
IL64498A (en) 1985-08-30
DD202867A5 (de) 1983-10-05
ZA818529B (en) 1983-08-31
YU290381A (en) 1983-10-31
ES512915A0 (es) 1983-03-01
PT74112B (de) 1984-10-09
ES8304536A1 (es) 1983-03-01
PH21599A (en) 1987-12-11
ES512913A0 (es) 1983-03-01
ES8304538A1 (es) 1983-03-01
GB2088873B (en) 1984-10-17
ES512914A0 (es) 1983-03-01
BE891416A (fr) 1982-06-09
HU185676B (en) 1985-03-28
GB2088873A (en) 1982-06-16
LU83830A1 (de) 1983-04-13
SU1172449A3 (ru) 1985-08-07
CH651541A5 (de) 1985-09-30
PL129385B1 (en) 1984-05-31
CA1202636A (en) 1986-04-01
ES507635A0 (es) 1983-01-01
DE3146623A1 (de) 1982-07-15
FR2498596A1 (fr) 1982-07-30
DK541981A (da) 1982-06-11
IT1172129B (it) 1987-06-18
NL8105170A (nl) 1982-07-01
NZ199215A (en) 1986-07-11
GR77323B (enrdf_load_stackoverflow) 1984-09-11
NO152649B (no) 1985-07-22
NO152649C (no) 1985-10-30
PT74112A (de) 1982-01-01
ES8304537A1 (es) 1983-03-01
SE8107387L (sv) 1982-07-26
FR2498596B1 (fr) 1986-03-21
FI813934L (fi) 1982-06-11
FI813934A7 (fi) 1982-06-11
CS229924B2 (en) 1984-07-16
AR227802A1 (es) 1982-12-15
AU547655B2 (en) 1985-10-31
IE812888L (en) 1982-06-10
KR830007505A (ko) 1983-10-21
IT8149853A0 (it) 1981-12-07
AT379378B (de) 1985-12-27

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19811214

PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19821229

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19811214

Comment text: Patent Application

PG1501 Laying open of application
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19860530

Patent event code: PE09021S01D

PG1605 Publication of application before grant of patent

Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19861230

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19870422