KR850001284A - 키브델로스포렌지움 애리덤(kibdelosporangium aridum)쉬어리(shearer)젠.노브., 에스.피.노브.(gen. nov., sp. nov.)atcc 39323에 의해 생산되는 항생물질들 - Google Patents
키브델로스포렌지움 애리덤(kibdelosporangium aridum)쉬어리(shearer)젠.노브., 에스.피.노브.(gen. nov., sp. nov.)atcc 39323에 의해 생산되는 항생물질들 Download PDFInfo
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- KR850001284A KR850001284A KR1019840004085A KR840004085A KR850001284A KR 850001284 A KR850001284 A KR 850001284A KR 1019840004085 A KR1019840004085 A KR 1019840004085A KR 840004085 A KR840004085 A KR 840004085A KR 850001284 A KR850001284 A KR 850001284A
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- 241000203796 Kibdelosporangium aridum Species 0.000 title claims 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- ZHRODENVJFUAFN-PNKCYDOPSA-N aad 216 Chemical compound CCC(=O)N[C@H]1C(O)O[C@H](C(O)=O)[C@@H](O)[C@@H]1O.N1C(=O)C(NC(C(NC)C=2C=C(O3)C(O)=CC=2)=O)C(O)C(C=C2Cl)=CC=C2OC(C=2O)=CC4=CC=2OC(C(=C2)Cl)=C(Cl)C=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C5C=2)C(O)=O)=O)NC(=O)C5NC(=O)C4NC(=O)C1C1=CC3=CC(O)=C1Cl ZHRODENVJFUAFN-PNKCYDOPSA-N 0.000 claims 6
- 238000000034 method Methods 0.000 claims 4
- 230000003115 biocidal effect Effects 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 238000000855 fermentation Methods 0.000 claims 2
- 230000004151 fermentation Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 230000000536 complexating effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000011033 desalting Methods 0.000 claims 1
- 238000011031 large-scale manufacturing process Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/04—Actinomyces
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 키브델로스포렌지움 애리덤(KIBDELOSPORANGIUM ARIDUM)쉬어리(Shearer)젠.노브., 에스.노브.(gen. nov., sp. nov.)ATCC 39323에 미생물 혹은 그 변종을 침수된 호기성 상태하에서 동화될 수 있는 탄소 및 질소원천을 함유하는 수용성 자양배지에서 AAD 216 복합체의 실질적인 양이 생산될때까지의 배양과 그렇게 생산된 AAD 216 복합체의 분리에 의한, 항생물질 AAD 216 복합체의 대규모 생산방법.
- AAD 216 복합체를 함유하는 총발효 혼합물을 정제시키고, 그 정제된 혼합물을 산으로 침전시킴으로써, 발효매체로부터 AAD 216복합체를 회수하는 방법을 포함하는, 청구범위 제1항에 따른 방법.
- 크로마토그라피를 이용하여 AAD 216복합체로부터, 항생물질 요소인 AAD216A, AAD216B 및/혹은 AAD216C를 분리해 내는 방법으로 구성되는 청구범위 제2항에 따른 방법.
- 항생물질요소를 탈염시켜 순수한 상태의 AAD216A, AAD216B, 및 AAD216C를 얻는 것으로 구성되는 청구범위 제3항에 따른 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/513,513 US4548974A (en) | 1983-07-13 | 1983-07-13 | Antibiotics produced by Kibdelosporangium aridum shearer |
US513513 | 1983-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR850001284A true KR850001284A (ko) | 1985-03-18 |
Family
ID=24043597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840004085A KR850001284A (ko) | 1983-07-13 | 1984-07-12 | 키브델로스포렌지움 애리덤(kibdelosporangium aridum)쉬어리(shearer)젠.노브., 에스.피.노브.(gen. nov., sp. nov.)atcc 39323에 의해 생산되는 항생물질들 |
Country Status (23)
Country | Link |
---|---|
US (1) | US4548974A (ko) |
EP (1) | EP0132118B1 (ko) |
JP (5) | JPH0695941B2 (ko) |
KR (1) | KR850001284A (ko) |
AT (1) | ATE47142T1 (ko) |
AU (1) | AU587565B2 (ko) |
CA (1) | CA1210721A (ko) |
DE (1) | DE3480092D1 (ko) |
DK (1) | DK163001C (ko) |
DZ (1) | DZ658A1 (ko) |
ES (1) | ES8505723A1 (ko) |
FI (1) | FI77690C (ko) |
GR (1) | GR81517B (ko) |
HK (1) | HK50193A (ko) |
HU (1) | HU193213B (ko) |
IE (1) | IE57727B1 (ko) |
IL (1) | IL72369A (ko) |
NO (1) | NO158814C (ko) |
NZ (1) | NZ208849A (ko) |
PH (1) | PH22062A (ko) |
PT (1) | PT78877B (ko) |
ZA (1) | ZA845336B (ko) |
ZW (1) | ZW10784A1 (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4548974A (en) * | 1983-07-13 | 1985-10-22 | Smithkline Beckman Corporation | Antibiotics produced by Kibdelosporangium aridum shearer |
EP0211490B1 (en) | 1985-06-20 | 1992-02-26 | Smithkline Beecham Corporation | Antibiotics of the vancomycin-class |
US4694069A (en) * | 1985-09-30 | 1987-09-15 | Smithkline Beckman Corporation | Kibdelosporangium aridum SK&F-AAD-609 |
US4797280A (en) * | 1986-06-10 | 1989-01-10 | Smithkline Beckman Corporation | Antibiotics produced by Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 |
US4742045A (en) * | 1986-07-30 | 1988-05-03 | Smithkline Beckman Corporation | Glycopeptide antibiotics |
MX9204281A (es) * | 1991-07-24 | 1993-04-01 | Smithkline Beecham Corp | Composiciones alimenticias antibioticas y metodo para mejorar la eficiencia alimenticia y promover el crecimiento en animales monogastricos |
KR0179447B1 (ko) * | 1996-12-10 | 1999-02-01 | 황춘근 | 골프공 |
KR0179448B1 (ko) * | 1996-12-26 | 1999-02-01 | 황춘근 | 골프공 |
US6787040B2 (en) * | 2000-05-16 | 2004-09-07 | Immunocept, L.L.C. | Method and system for colloid exchange therapy |
AU2003900927A0 (en) * | 2003-02-28 | 2003-03-13 | Biodiem Ltd | Growth promotion method |
ES2368236B1 (es) * | 2009-12-23 | 2012-09-26 | Merck Sharp & Dohme Corp. | Agentes antibacterianos. |
CN104830815B (zh) * | 2015-06-02 | 2018-02-23 | 江南大学 | 一种采用全细胞转化高效生产α‑苯丙酮酸的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4083964A (en) * | 1976-05-24 | 1978-04-11 | Eli Lilly And Company | Antibiotic A-35512 for increasing feed utilization efficiency in an animal |
US4378348A (en) * | 1979-12-28 | 1983-03-29 | Otsuka Pharmaceutical Co., Ltd. | OA-7653 Substance |
US4322406A (en) * | 1980-12-18 | 1982-03-30 | Eli Lilly And Company | Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1 |
US4548974A (en) * | 1983-07-13 | 1985-10-22 | Smithkline Beckman Corporation | Antibiotics produced by Kibdelosporangium aridum shearer |
US4667024A (en) * | 1983-07-13 | 1987-05-19 | Smithkline Beckman Corporation | Process for the preparation of purified vancomycin class antibiotics |
US4521335A (en) * | 1983-07-13 | 1985-06-04 | Smithkline Beckman Corporation | Aglycone and pseudo-aglycones of the AAD 216 antibiotics |
-
1983
- 1983-07-13 US US06/513,513 patent/US4548974A/en not_active Expired - Fee Related
-
1984
- 1984-07-05 PH PH30923A patent/PH22062A/en unknown
- 1984-07-09 AU AU30408/84A patent/AU587565B2/en not_active Ceased
- 1984-07-09 GR GR75243A patent/GR81517B/el unknown
- 1984-07-09 CA CA000458407A patent/CA1210721A/en not_active Expired
- 1984-07-09 ZW ZW107/84A patent/ZW10784A1/xx unknown
- 1984-07-10 DZ DZ847220A patent/DZ658A1/fr active
- 1984-07-10 IE IE1760/84A patent/IE57727B1/en not_active IP Right Cessation
- 1984-07-10 DK DK338784A patent/DK163001C/da not_active IP Right Cessation
- 1984-07-10 PT PT78877A patent/PT78877B/pt not_active IP Right Cessation
- 1984-07-10 IL IL72369A patent/IL72369A/xx not_active IP Right Cessation
- 1984-07-10 NZ NZ208849A patent/NZ208849A/en unknown
- 1984-07-11 AT AT84304735T patent/ATE47142T1/de not_active IP Right Cessation
- 1984-07-11 EP EP84304735A patent/EP0132118B1/en not_active Expired
- 1984-07-11 ZA ZA845336A patent/ZA845336B/xx unknown
- 1984-07-11 DE DE8484304735T patent/DE3480092D1/de not_active Expired
- 1984-07-12 FI FI842807A patent/FI77690C/fi not_active IP Right Cessation
- 1984-07-12 HU HU842726A patent/HU193213B/hu not_active IP Right Cessation
- 1984-07-12 KR KR1019840004085A patent/KR850001284A/ko not_active Application Discontinuation
- 1984-07-12 ES ES534248A patent/ES8505723A1/es not_active Expired
- 1984-07-12 NO NO842863A patent/NO158814C/no unknown
- 1984-07-12 JP JP59145866A patent/JPH0695941B2/ja not_active Expired - Lifetime
-
1993
- 1993-05-20 HK HK501/93A patent/HK50193A/xx not_active IP Right Cessation
- 1993-06-30 JP JP5161302A patent/JPH08835B2/ja not_active Expired - Lifetime
- 1993-12-27 JP JP5331312A patent/JP2603047B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-14 JP JP7147299A patent/JP2594777B2/ja not_active Expired - Lifetime
- 1995-06-14 JP JP7147301A patent/JP2594778B2/ja not_active Expired - Lifetime
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