KR830009011A - 신규 구아니디노시 클로헥산카복실산 유도체 및 그의 제법 - Google Patents

신규 구아니디노시 클로헥산카복실산 유도체 및 그의 제법 Download PDF

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Publication number
KR830009011A
KR830009011A KR1019820000269A KR820000269A KR830009011A KR 830009011 A KR830009011 A KR 830009011A KR 1019820000269 A KR1019820000269 A KR 1019820000269A KR 820000269 A KR820000269 A KR 820000269A KR 830009011 A KR830009011 A KR 830009011A
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KR
South Korea
Prior art keywords
group
halogen atom
guanidinosyl
novel
preparation
Prior art date
Application number
KR1019820000269A
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English (en)
Other versions
KR880001104B1 (ko
Inventor
마쯔 무쓰미 무라
도시오 사또오
히로야스 세끼네
야쓰시 덴도
요시오 기가와
가나메 곤도오
Original Assignee
야마 구찌 아끼라
닛뽕 케미파 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP728681A external-priority patent/JPS57122060A/ja
Priority claimed from JP728481A external-priority patent/JPS57122061A/ja
Priority claimed from JP728381A external-priority patent/JPS57122059A/ja
Priority claimed from JP1083281A external-priority patent/JPS57126463A/ja
Priority claimed from JP1083181A external-priority patent/JPS57126462A/ja
Application filed by 야마 구찌 아끼라, 닛뽕 케미파 가부시끼 가이샤 filed Critical 야마 구찌 아끼라
Publication of KR830009011A publication Critical patent/KR830009011A/ko
Application granted granted Critical
Publication of KR880001104B1 publication Critical patent/KR880001104B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

신규 구아니디노시 클로헥산카복실산 유도체 및 그의 제법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 4-구아니디노 메틸시클로 헥산카복실산 또는 그의 반응성 유도체를 일반식(II)의 화합물 또는 그의 반응성 유도체와 반응시킴을 특징으로 하여 일반식(I)의 구아니디노 시클로헥산 카복실산 유도체 및 그의 염을 제조하는 방법.
    상기식에서
    R1은 인다닐, 인들릴, 퀴놀릴, 또는 크로모닐그룹, 일반식의 그룹
    (여기서 R2는 할로겐원자 또는 니트로그룹이다), 또는 일반식의 그룹(여기서 R3는 할로겐원자, 알킬, 니트로, 시아노, 아세트아미노, 아미노설포닐, 벤조일, 페녹시, 트리플루오로메틸 그룹이고, R4는 수소 또는 할로겐원자 또는 알킬그룹이고, R5는 수소 또는 할로겐원자, 또는 알킬 그룹이다)을 뜻한다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR8200269A 1981-01-22 1982-01-22 구아니디노시클로헥산카복실산 유도체의 제조방법 KR880001104B1 (ko)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP728681A JPS57122060A (en) 1981-01-22 1981-01-22 Carboxylic acid ester and its preparation
JP7286 1981-01-22
JP7283 1981-01-22
JP728481A JPS57122061A (en) 1981-01-22 1981-01-22 Novel cyclohexanecarboxylic acid derivative and its preparation
JP728381A JPS57122059A (en) 1981-01-22 1981-01-22 Novel cyclohexanecarboxylic acid derivative and its preparation
JP7284 1981-01-22
JP1083281A JPS57126463A (en) 1981-01-29 1981-01-29 Novel carboxylic ester and its preparation
JP1083181A JPS57126462A (en) 1981-01-29 1981-01-29 Novel carboxylic ester and its preparation
JP10831 1981-01-29
JP10832 1981-01-29

Publications (2)

Publication Number Publication Date
KR830009011A true KR830009011A (ko) 1983-12-17
KR880001104B1 KR880001104B1 (ko) 1988-06-29

Family

ID=27518804

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8200269A KR880001104B1 (ko) 1981-01-22 1982-01-22 구아니디노시클로헥산카복실산 유도체의 제조방법

Country Status (11)

Country Link
US (1) US4465851A (ko)
KR (1) KR880001104B1 (ko)
BE (1) BE891790A (ko)
BR (1) BR8200212A (ko)
CA (1) CA1180716A (ko)
CH (1) CH652119A5 (ko)
DE (1) DE3201817A1 (ko)
FR (1) FR2498183A1 (ko)
IT (1) IT1191163B (ko)
NL (1) NL8200110A (ko)
SE (1) SE455789B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69316681T2 (de) * 1992-08-27 1998-05-14 Shiseido Co Ltd Äusserliche, auf der Haut anzuwendende Depigmentierungsmittel enthaltende Zusammensetzung
ES2214802T3 (es) * 1994-08-30 2004-09-16 Nagase Chemtex Corporation Intermedios para la preparacion de derivados de esteres de acido guanidinometilciclohexanocarboxilico.
AUPO227896A0 (en) * 1996-09-13 1996-10-03 Fujisawa Pharmaceutical Co., Ltd. Novel compounds and their preparation
EA003101B1 (ru) 1998-03-19 2002-12-26 Бристол-Майерз Сквибб Компани Двухфазная система доставки с регулируемым высвобождением для фармацевтических средств с высокой растворимостью и способ лечения диабета с помощью этой системы
GB9908410D0 (en) 1999-04-13 1999-06-09 Pfizer Ltd Pyridines
MX342120B (es) 2010-07-09 2016-09-14 William Owen Wilkison Combinación de sistema de liberación prolongada/inmediata para productos farmacéuticos de vida media corta como el remogliflozin.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3699149A (en) * 1968-10-14 1972-10-17 Daiichi Seiyaku Co Phenyl esters of t-amcha
JPS5339419B2 (ko) * 1972-10-19 1978-10-21
JPS5140075A (ja) * 1974-09-30 1976-04-03 Tokyo Shibaura Electric Co Handotaisochiseizohoho
JPS5645454A (en) * 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid derivative and its preparation
AU541738B2 (en) * 1979-09-20 1985-01-17 Nippon Chemiphar Co. Ltd. Cyclohexane carboxylic acid derivatives

Also Published As

Publication number Publication date
NL8200110A (nl) 1982-08-16
CA1180716A (en) 1985-01-08
US4465851A (en) 1984-08-14
IT8267060A0 (it) 1982-01-21
CH652119A5 (fr) 1985-10-31
DE3201817C2 (ko) 1991-03-07
FR2498183A1 (fr) 1982-07-23
BR8200212A (pt) 1982-11-09
BE891790A (fr) 1982-04-30
FR2498183B1 (ko) 1985-05-10
DE3201817A1 (de) 1982-08-19
SE8200309L (sv) 1982-07-23
IT1191163B (it) 1988-02-24
KR880001104B1 (ko) 1988-06-29
SE455789B (sv) 1988-08-08

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