KR830007597A - 3-아릴-5-이소티아졸 유도체의 제조방법 - Google Patents

3-아릴-5-이소티아졸 유도체의 제조방법 Download PDF

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Publication number
KR830007597A
KR830007597A KR1019810003537A KR810003537A KR830007597A KR 830007597 A KR830007597 A KR 830007597A KR 1019810003537 A KR1019810003537 A KR 1019810003537A KR 810003537 A KR810003537 A KR 810003537A KR 830007597 A KR830007597 A KR 830007597A
Authority
KR
South Korea
Prior art keywords
formula
hydroxy
compound
ester
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
KR1019810003537A
Other languages
English (en)
Korean (ko)
Inventor
리챠드 벡 제임스
피터 가유스키 로버트
어빈 하클러 로날드
Original Assignee
아더 알. 웨일
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아더 알. 웨일, 일라이 릴리 앤드 캄파니 filed Critical 아더 알. 웨일
Publication of KR830007597A publication Critical patent/KR830007597A/ko
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019810003537A 1980-09-22 1981-09-22 3-아릴-5-이소티아졸 유도체의 제조방법 Abandoned KR830007597A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US189435 1980-09-22
US06/189,435 US4346094A (en) 1980-09-22 1980-09-22 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels

Publications (1)

Publication Number Publication Date
KR830007597A true KR830007597A (ko) 1983-11-04

Family

ID=22697314

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810003537A Abandoned KR830007597A (ko) 1980-09-22 1981-09-22 3-아릴-5-이소티아졸 유도체의 제조방법

Country Status (22)

Country Link
US (1) US4346094A (https=)
EP (1) EP0048615B1 (https=)
JP (1) JPS5785379A (https=)
KR (1) KR830007597A (https=)
AR (1) AR229103A1 (https=)
AT (1) ATE7657T1 (https=)
AU (1) AU7551681A (https=)
CS (1) CS228536B2 (https=)
DD (1) DD201790A5 (https=)
DE (1) DE3163900D1 (https=)
DK (1) DK417981A (https=)
ES (1) ES505678A0 (https=)
FI (1) FI812940A7 (https=)
GB (1) GB2084573B (https=)
GR (1) GR75046B (https=)
IL (1) IL63890A0 (https=)
NO (1) NO813208L (https=)
PL (1) PL130497B1 (https=)
PT (1) PT73711B (https=)
RO (1) RO82216A (https=)
YU (1) YU227181A (https=)
ZA (1) ZA816549B (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431652A (en) * 1980-12-29 1984-02-14 Merck & Co., Inc. 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis
US4428956A (en) 1980-12-29 1984-01-31 Merck & Co., Inc. 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis
US4539328A (en) * 1983-03-25 1985-09-03 Fmc Corporation Nematicidal isothiazole derivatives
US4620865A (en) * 1983-11-07 1986-11-04 Eli Lilly And Company Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
ZW21687A1 (en) * 1986-12-12 1988-07-20 Hoffmann La Roche Triazine derivatives
ES2092580T3 (es) * 1990-11-30 1996-12-01 Teijin Ltd Derivado de 2-ariltiazol y composicion farmaceutica que contiene el mismo.
US5294630A (en) * 1992-07-07 1994-03-15 Eli Lilly And Company Treatment of inflammatory bowel disease
US5436258A (en) * 1992-09-09 1995-07-25 Eli Lilly And Company Prevention of bone resorption
MY117352A (en) * 1995-10-31 2004-06-30 Ciba Sc Holding Ag Oximesulfonic acid esters and the use thereof as latent sulfonic acids.
ID21775A (id) * 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
AU1520699A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Methods for treatment of disorders of cardiac contractility
TW575792B (en) * 1998-08-19 2004-02-11 Ciba Sc Holding Ag New unsaturated oxime derivatives and the use thereof as latent acids
SG78412A1 (en) 1999-03-31 2001-02-20 Ciba Sc Holding Ag Oxime derivatives and the use thereof as latent acids
KR20040089607A (ko) 2002-02-06 2004-10-21 시바 스페셜티 케미칼스 홀딩 인크. 설포네이트 유도체 및 잠산으로서의 이의 용도
EP1783124A4 (en) * 2004-08-27 2009-07-08 Astellas Pharma Inc 2-PHENYLTHIOPHENDERIVAT
JP4894517B2 (ja) * 2004-08-27 2012-03-14 アステラス製薬株式会社 ２−フェニルピリジン誘導体
CN101282934A (zh) 2005-10-07 2008-10-08 安斯泰来制药株式会社 三芳基羧酸衍生物
ATE555810T1 (de) 2006-02-24 2012-05-15 Astellas Pharma Inc Mittel zur behandlung oder prävention von verdauungsgeschwüren
GB2450975B (en) 2007-07-12 2010-02-24 Ciba Holding Inc Yellow radiation curing inks
US8791077B2 (en) * 2008-05-22 2014-07-29 Astrazeneca Ab Method for treating hyperuricemia employing an SGLT2 inhibitor and composition containing same
SG173884A1 (en) 2009-02-27 2011-10-28 Teijin Pharma Ltd Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst
WO2010112408A1 (en) 2009-03-30 2010-10-07 Basf Se Uv-dose indicator films
SG187843A1 (en) 2010-08-27 2013-03-28 Teijin Pharma Ltd Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using a palladium compound
KR101897842B1 (ko) 2011-01-28 2018-09-12 바스프 에스이 열 경화제로서 옥심 술포네이트를 포함하는 중합성 조성물
CN105189476B (zh) * 2013-03-29 2017-07-07 帝人制药株式会社 吡唑衍生物
US10487050B2 (en) 2014-08-29 2019-11-26 Basf Se Oxime sulfonate derivatives
WO2016174192A1 (de) 2015-04-29 2016-11-03 Bsn Medical Gmbh Medizinische badevorrichtung
AU2016256186B2 (en) 2015-04-29 2020-01-16 Bsn Medical Gmbh Multi-step process for no production

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178604A (en) * 1966-03-21 1970-01-21 American Cyanamid Co Novel Pyridinium Salts and Methods for Preparing Same
US3464999A (en) * 1967-07-27 1969-09-02 R & L Molecular Research Ltd Thiadiazolylisothiazoles
GB1180268A (en) * 1967-09-26 1970-02-04 Ici Ltd Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives
GB1192701A (en) * 1968-03-22 1970-05-20 Ici Ltd Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same
US3681498A (en) * 1970-10-19 1972-08-01 American Cyanamid Co Isothiazolyl pyridinium salts as hypoglycemic agents

Also Published As

Publication number Publication date
AU7551681A (en) 1982-04-01
IL63890A0 (en) 1981-12-31
CS228536B2 (en) 1984-05-14
EP0048615B1 (en) 1984-05-30
PL233103A1 (https=) 1982-12-20
RO82216A (ro) 1983-07-07
AR229103A1 (es) 1983-06-15
NO813208L (no) 1982-03-23
DK417981A (da) 1982-03-23
YU227181A (en) 1983-10-31
GR75046B (https=) 1984-07-12
DE3163900D1 (en) 1984-07-05
RO82216B (ro) 1983-06-30
ZA816549B (en) 1983-04-27
GB2084573A (en) 1982-04-15
ES8301225A1 (es) 1982-12-01
ES505678A0 (es) 1982-12-01
EP0048615A1 (en) 1982-03-31
GB2084573B (en) 1984-09-12
FI812940L (fi) 1982-03-23
DD201790A5 (de) 1983-08-10
JPS5785379A (en) 1982-05-28
US4346094A (en) 1982-08-24
ATE7657T1 (de) 1984-06-15
PL130497B1 (en) 1984-08-31
PT73711A (en) 1981-10-01
PT73711B (en) 1982-12-20
FI812940A7 (fi) 1982-03-23

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19810922

PG1501 Laying open of application
PC1902 Submission of document of abandonment before decision of registration