ES505678A0 - Un procedimiento para la preparacion de un derivado de 3- aril-5-isotiazol - Google Patents

Un procedimiento para la preparacion de un derivado de 3- aril-5-isotiazol

Info

Publication number
ES505678A0
ES505678A0 ES505678A ES505678A ES505678A0 ES 505678 A0 ES505678 A0 ES 505678A0 ES 505678 A ES505678 A ES 505678A ES 505678 A ES505678 A ES 505678A ES 505678 A0 ES505678 A0 ES 505678A0
Authority
ES
Spain
Prior art keywords
isotiazole
aril
derivative
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES505678A
Other languages
English (en)
Other versions
ES8301225A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES8301225A1 publication Critical patent/ES8301225A1/es
Publication of ES505678A0 publication Critical patent/ES505678A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES505678A 1980-09-22 1981-09-21 Un procedimiento para la preparacion de un derivado de 3- aril-5-isotiazol Granted ES505678A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/189,435 US4346094A (en) 1980-09-22 1980-09-22 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels

Publications (2)

Publication Number Publication Date
ES8301225A1 ES8301225A1 (es) 1982-12-01
ES505678A0 true ES505678A0 (es) 1982-12-01

Family

ID=22697314

Family Applications (1)

Application Number Title Priority Date Filing Date
ES505678A Granted ES505678A0 (es) 1980-09-22 1981-09-21 Un procedimiento para la preparacion de un derivado de 3- aril-5-isotiazol

Country Status (22)

Country Link
US (1) US4346094A (es)
EP (1) EP0048615B1 (es)
JP (1) JPS5785379A (es)
KR (1) KR830007597A (es)
AR (1) AR229103A1 (es)
AT (1) ATE7657T1 (es)
AU (1) AU7551681A (es)
CS (1) CS228536B2 (es)
DD (1) DD201790A5 (es)
DE (1) DE3163900D1 (es)
DK (1) DK417981A (es)
ES (1) ES505678A0 (es)
FI (1) FI812940L (es)
GB (1) GB2084573B (es)
GR (1) GR75046B (es)
IL (1) IL63890A0 (es)
NO (1) NO813208L (es)
PL (1) PL130497B1 (es)
PT (1) PT73711B (es)
RO (1) RO82216A (es)
YU (1) YU227181A (es)
ZA (1) ZA816549B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431652A (en) * 1980-12-29 1984-02-14 Merck & Co., Inc. 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis
US4428956A (en) 1980-12-29 1984-01-31 Merck & Co., Inc. 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis
US4539328A (en) * 1983-03-25 1985-09-03 Fmc Corporation Nematicidal isothiazole derivatives
US4620865A (en) * 1983-11-07 1986-11-04 Eli Lilly And Company Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
ZW21687A1 (en) * 1986-12-12 1988-07-20 Hoffmann La Roche Triazine derivatives
DK0513379T3 (da) * 1990-11-30 1996-09-30 Teijin Ltd 2-Arylthiazolderivater og farmaceutisk præparat indeholdende sådanne
US5294630A (en) * 1992-07-07 1994-03-15 Eli Lilly And Company Treatment of inflammatory bowel disease
US5436258A (en) * 1992-09-09 1995-07-25 Eli Lilly And Company Prevention of bone resorption
MY117352A (en) * 1995-10-31 2004-06-30 Ciba Sc Holding Ag Oximesulfonic acid esters and the use thereof as latent sulfonic acids.
ID21775A (id) * 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
AU1520699A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Methods for treatment of disorders of cardiac contractility
TW575792B (en) * 1998-08-19 2004-02-11 Ciba Sc Holding Ag New unsaturated oxime derivatives and the use thereof as latent acids
SG78412A1 (en) 1999-03-31 2001-02-20 Ciba Sc Holding Ag Oxime derivatives and the use thereof as latent acids
CA2474532A1 (en) 2002-02-06 2003-08-14 Peter Murer Sulfonate derivatives and the use therof as latent acids
EP1783124A4 (en) * 2004-08-27 2009-07-08 Astellas Pharma Inc 2-PHENYLTHIOPHENDERIVAT
US7820700B2 (en) * 2004-08-27 2010-10-26 Astellas Pharma Inc. 2-phenylpyridine derivative
WO2007043457A1 (ja) 2005-10-07 2007-04-19 Astellas Pharma Inc. トリアリールカルボン酸誘導体
CN101389352B (zh) 2006-02-24 2012-09-19 安斯泰来制药株式会社 治疗或预防消化道溃疡的药物
GB2450975B (en) 2007-07-12 2010-02-24 Ciba Holding Inc Yellow radiation curing inks
BRPI0913129A2 (pt) * 2008-05-22 2016-01-05 Bristol Myers Squibb Co método para tratamento de hiperuricemia empregando um inibidor de sglt2 e composição contendo o mesmo
CN102333765B (zh) 2009-02-27 2015-01-14 帝人制药株式会社 基于使用过渡金属催化剂的偶联法的苯基取代杂环衍生物的制造方法
EP2414894B1 (en) 2009-03-30 2014-02-12 Basf Se Uv-dose indicator films
KR101800054B1 (ko) 2010-08-27 2017-11-21 데이진 화-마 가부시키가이샤 팔라듐 화합물을 사용한 커플링법에 의한 페닐 치환 복소 고리 유도체의 제조법
WO2012101245A1 (en) 2011-01-28 2012-08-02 Basf Se Polymerizable composition comprising an oxime sulfonate as thermal curing agent
HUE037813T2 (hu) * 2013-03-29 2018-09-28 Teijin Pharma Ltd Pirazolszármazék
KR20170048422A (ko) 2014-08-29 2017-05-08 바스프 에스이 옥심 술포네이트 유도체
WO2016174043A1 (de) 2015-04-29 2016-11-03 Bsn Medical Gmbh Mehrstufiges verfahren zur no-herstellung
WO2016174192A1 (de) 2015-04-29 2016-11-03 Bsn Medical Gmbh Medizinische badevorrichtung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178604A (en) * 1966-03-21 1970-01-21 American Cyanamid Co Novel Pyridinium Salts and Methods for Preparing Same
US3464999A (en) * 1967-07-27 1969-09-02 R & L Molecular Research Ltd Thiadiazolylisothiazoles
GB1180268A (en) * 1967-09-26 1970-02-04 Ici Ltd Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives
GB1192701A (en) * 1968-03-22 1970-05-20 Ici Ltd Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same
US3681498A (en) * 1970-10-19 1972-08-01 American Cyanamid Co Isothiazolyl pyridinium salts as hypoglycemic agents

Also Published As

Publication number Publication date
PT73711B (en) 1982-12-20
DD201790A5 (de) 1983-08-10
PL233103A1 (es) 1982-12-20
FI812940L (fi) 1982-03-23
IL63890A0 (en) 1981-12-31
US4346094A (en) 1982-08-24
DK417981A (da) 1982-03-23
PT73711A (en) 1981-10-01
EP0048615B1 (en) 1984-05-30
RO82216B (ro) 1983-06-30
ATE7657T1 (de) 1984-06-15
GB2084573A (en) 1982-04-15
RO82216A (ro) 1983-07-07
ES8301225A1 (es) 1982-12-01
AR229103A1 (es) 1983-06-15
GB2084573B (en) 1984-09-12
CS228536B2 (en) 1984-05-14
JPS5785379A (en) 1982-05-28
KR830007597A (ko) 1983-11-04
ZA816549B (en) 1983-04-27
NO813208L (no) 1982-03-23
DE3163900D1 (en) 1984-07-05
AU7551681A (en) 1982-04-01
YU227181A (en) 1983-10-31
GR75046B (es) 1984-07-12
PL130497B1 (en) 1984-08-31
EP0048615A1 (en) 1982-03-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010201