DE3788149D1 - Prostazyklin-(PGI2)-Analoge. - Google Patents

Prostazyklin-(PGI2)-Analoge.

Info

Publication number
DE3788149D1
DE3788149D1 DE87104669T DE3788149T DE3788149D1 DE 3788149 D1 DE3788149 D1 DE 3788149D1 DE 87104669 T DE87104669 T DE 87104669T DE 3788149 T DE3788149 T DE 3788149T DE 3788149 D1 DE3788149 D1 DE 3788149D1
Authority
DE
Germany
Prior art keywords
pgi2
hydrogen
straight
alkyl
prostacycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87104669T
Other languages
English (en)
Other versions
DE3788149T2 (de
Inventor
Sachio Mori
Hikozo Iwakura
Shozo Takechi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3788149D1 publication Critical patent/DE3788149D1/de
Publication of DE3788149T2 publication Critical patent/DE3788149T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Paper (AREA)
  • Vending Machines For Individual Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE87104669T 1986-03-31 1987-03-30 Prostazyklin-(PGI2)-Analoge. Expired - Fee Related DE3788149T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7493286 1986-03-31

Publications (2)

Publication Number Publication Date
DE3788149D1 true DE3788149D1 (de) 1993-12-23
DE3788149T2 DE3788149T2 (de) 1994-04-07

Family

ID=13561619

Family Applications (2)

Application Number Title Priority Date Filing Date
DE87104669T Expired - Fee Related DE3788149T2 (de) 1986-03-31 1987-03-30 Prostazyklin-(PGI2)-Analoge.
DE198787104669T Pending DE240890T1 (de) 1986-03-31 1987-03-30 Prostazyklin-(pgi2)-analoge.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198787104669T Pending DE240890T1 (de) 1986-03-31 1987-03-30 Prostazyklin-(pgi2)-analoge.

Country Status (7)

Country Link
US (2) US4820836A (de)
EP (1) EP0240890B1 (de)
JP (1) JPH07121907B2 (de)
AT (1) ATE97404T1 (de)
CA (1) CA1284642C (de)
DE (2) DE3788149T2 (de)
ES (1) ES2008067T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227157B1 (en) * 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7790362B2 (en) * 2003-07-08 2010-09-07 Accumetrics, Inc. Controlled platelet activation to monitor therapy of ADP antagonists
US7595169B2 (en) * 2005-04-27 2009-09-29 Accumetrics, Inc. Method for determining percent platelet aggregation
ES2387700T3 (es) * 2007-05-03 2012-09-28 Accumetrics, Inc. Métodos para medir la inhibición de la agregación de plaquetas mediante antagonistas del receptor de trombina
WO2010027875A2 (en) 2008-08-27 2010-03-11 Calcimedica Inc. Compounds that modulate intracellular calcium
US8524763B2 (en) 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3006865A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Hetero-imino-prostacycline
US4496742A (en) * 1981-10-13 1985-01-29 The Upjohn Company Analogs of 5,6-dihydro PGI2
US4588823A (en) * 1982-02-16 1986-05-13 The Upjohn Company 9-substituted carbacyclin analogs
US4487960A (en) * 1982-04-19 1984-12-11 The Upjohn Company 9-Substituted carbacyclin analogs

Also Published As

Publication number Publication date
EP0240890B1 (de) 1993-11-18
ATE97404T1 (de) 1993-12-15
JPS6366168A (ja) 1988-03-24
DE240890T1 (de) 1988-04-28
DE3788149T2 (de) 1994-04-07
ES2008067A4 (es) 1989-07-16
US4855449A (en) 1989-08-08
ES2008067T3 (es) 1994-11-16
JPH07121907B2 (ja) 1995-12-25
EP0240890A2 (de) 1987-10-14
CA1284642C (en) 1991-06-04
US4820836A (en) 1989-04-11
EP0240890A3 (en) 1989-05-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee