ATE46501T1 - Abkoemmlinge der guanidinomethylbenzoesaeure. - Google Patents

Abkoemmlinge der guanidinomethylbenzoesaeure.

Info

Publication number
ATE46501T1
ATE46501T1 AT86110197T AT86110197T ATE46501T1 AT E46501 T1 ATE46501 T1 AT E46501T1 AT 86110197 T AT86110197 T AT 86110197T AT 86110197 T AT86110197 T AT 86110197T AT E46501 T1 ATE46501 T1 AT E46501T1
Authority
AT
Austria
Prior art keywords
guanidinomethylbenzoacids
dergents
formula
afore
salt
Prior art date
Application number
AT86110197T
Other languages
English (en)
Inventor
Toshio Satoh
Hitoshi Matsumoto
Hisao Kakegawa
Original Assignee
Med Creat Kk
Sato Toshio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Med Creat Kk, Sato Toshio filed Critical Med Creat Kk
Application granted granted Critical
Publication of ATE46501T1 publication Critical patent/ATE46501T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT86110197T 1985-07-30 1986-07-24 Abkoemmlinge der guanidinomethylbenzoesaeure. ATE46501T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60166903A JPS6229566A (ja) 1985-07-30 1985-07-30 新規グアニジノメチル安息香酸誘導体
EP86110197A EP0218027B1 (de) 1985-07-30 1986-07-24 Abkömmlinge der Guanidinomethylbenzoesäure

Publications (1)

Publication Number Publication Date
ATE46501T1 true ATE46501T1 (de) 1989-10-15

Family

ID=15839768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86110197T ATE46501T1 (de) 1985-07-30 1986-07-24 Abkoemmlinge der guanidinomethylbenzoesaeure.

Country Status (7)

Country Link
US (1) US4732916A (de)
EP (1) EP0218027B1 (de)
JP (1) JPS6229566A (de)
AT (1) ATE46501T1 (de)
DE (1) DE3665711D1 (de)
ES (1) ES2001341A6 (de)
PT (1) PT83104B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63126860A (ja) * 1986-11-17 1988-05-30 Nippon Haipotsukusu:Kk グアニジノメチル安息香酸誘導体
US4948901A (en) * 1988-05-24 1990-08-14 Pfizer Inc. Benzamide protease inhibitors
US4970318A (en) * 1988-05-24 1990-11-13 Pfizer Inc. Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
US4874864A (en) * 1988-05-24 1989-10-17 Pfizer Inc. Benzamide protease inhibitors
US4948891A (en) * 1988-05-24 1990-08-14 Pfizer Inc. Benzamide protease inhibitors
US5654451B1 (en) * 1993-01-14 2000-02-22 Magainin Pharma Amino acids and peptides having modified c-terminals and modified n-terminals
DE4305536A1 (de) * 1993-02-19 1994-08-25 Asche Ag Verwendung von Enzym-Inhibitoren zur Herstellung eines Arzneimittels
EP1195372A1 (de) * 1994-04-18 2002-04-10 Mitsubishi Pharma Corporation N-Heterozyklisch substitutierte Benzamid Deriviate mit antihypertensiver Wirkung
TW499412B (en) 1996-11-26 2002-08-21 Dimensional Pharm Inc Aminoguanidines and alkoxyguanidines as protease inhibitors
DZ3415A1 (fr) 2000-08-31 2002-03-07 Chiron Corp Guanidinobenzamides comme mc4-r agonistes.
PT1385823E (pt) 2001-04-09 2007-01-31 Novartis Vaccines & Diagnostic Compostos de guanidino como agonistas do receptor de melanocortina-4 (r-mc4)
CN1203055C (zh) * 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
US20030229025A1 (en) * 2002-02-25 2003-12-11 Chiron Corporation Intranasal administration of MC4-R agonists
DE60333937D1 (de) * 2002-05-23 2010-10-07 Novartis Vaccines & Diagnostic Substituierte quinazolinone verbindungen
AU2004249120B2 (en) * 2003-05-23 2008-07-24 Glaxosmithkline Guanidino-substituted quinazolinone compounds as MC4-R agonists
AU2004293012A1 (en) * 2003-11-19 2005-06-09 Rustum S. Boyce Quinazolinone compounds with reduced bioaccumulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479401A (en) * 1966-06-28 1969-11-18 Merck & Co Inc Guanidinoaryl and guanidinomethylaryl compounds
BE757956A (fr) * 1969-10-24 1971-04-23 Ici Ltd Composes antiviraux
SE460667B (sv) * 1979-09-20 1989-11-06 Nippon Chemiphar Co Cyklohexankarboxylsyraderivat, foerfarande foer framstaellning daerav samt naemnda derivat foer terapeutisk anvaendning
JPS57197256A (en) * 1981-05-28 1982-12-03 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxamide derivative and its preparation

Also Published As

Publication number Publication date
US4732916A (en) 1988-03-22
DE3665711D1 (de) 1989-10-26
JPS6229566A (ja) 1987-02-07
PT83104A (en) 1986-08-01
EP0218027A1 (de) 1987-04-15
PT83104B (en) 1987-12-23
ES2001341A6 (es) 1988-05-16
EP0218027B1 (de) 1989-09-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee