KR20240149454A - 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 - Google Patents
입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 Download PDFInfo
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- KR20240149454A KR20240149454A KR1020247033230A KR20247033230A KR20240149454A KR 20240149454 A KR20240149454 A KR 20240149454A KR 1020247033230 A KR1020247033230 A KR 1020247033230A KR 20247033230 A KR20247033230 A KR 20247033230A KR 20240149454 A KR20240149454 A KR 20240149454A
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- A61K39/4611—
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K39/4631—
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- A61K39/464412—
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/31—Chimeric antigen receptors [CAR]
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- A—HUMAN NECESSITIES
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- A61K40/00—Cellular immunotherapy
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- A61K40/42—Cancer antigens
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K2239/10—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the structure of the chimeric antigen receptor [CAR]
- A61K2239/11—Antigen recognition domain
- A61K2239/13—Antibody-based
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02P20/50—Improvements relating to the production of bulk chemicals
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
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- Epidemiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Microbiology (AREA)
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- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Sustainable Development (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Pathology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461983415P | 2014-04-23 | 2014-04-23 | |
| US61/983,415 | 2014-04-23 | ||
| PCT/US2015/027401 WO2015164675A1 (en) | 2014-04-23 | 2015-04-23 | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| KR1020227032825A KR20220136455A (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227032825A Division KR20220136455A (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240149454A true KR20240149454A (ko) | 2024-10-14 |
Family
ID=53055126
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247033230A Pending KR20240149454A (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
| KR1020167032823A Active KR102447958B1 (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
| KR1020227032825A Ceased KR20220136455A (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167032823A Active KR102447958B1 (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
| KR1020227032825A Ceased KR20220136455A (ko) | 2014-04-23 | 2015-04-23 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
Country Status (21)
| Country | Link |
|---|---|
| US (8) | US11400115B2 (https=) |
| EP (4) | EP4219687B1 (https=) |
| JP (5) | JP6759187B2 (https=) |
| KR (3) | KR20240149454A (https=) |
| CN (3) | CN113046321A (https=) |
| AU (3) | AU2015249554B2 (https=) |
| BR (1) | BR112016024579A2 (https=) |
| CA (1) | CA2946312A1 (https=) |
| DK (1) | DK4219687T3 (https=) |
| ES (2) | ES2995052T3 (https=) |
| FI (1) | FI4219687T3 (https=) |
| IL (5) | IL313845A (https=) |
| MA (2) | MA51794A (https=) |
| MX (2) | MX382541B (https=) |
| PH (1) | PH12016502112A1 (https=) |
| PL (1) | PL4219687T3 (https=) |
| PT (1) | PT4219687T (https=) |
| RU (1) | RU2763795C2 (https=) |
| SA (1) | SA516380118B1 (https=) |
| SG (1) | SG11201608862SA (https=) |
| WO (1) | WO2015164675A1 (https=) |
Families Citing this family (140)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100183558A1 (en) | 2008-10-17 | 2010-07-22 | Zhennan Lai | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
| ES3011307T3 (en) | 2012-02-23 | 2025-04-07 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| SI3132247T1 (sl) | 2014-04-16 | 2021-12-31 | Juno Therapeutics Gmbh | Postopki, kompleti in naprava za povečanje populacije celic |
| CA2946312A1 (en) | 2014-04-23 | 2015-10-29 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| CN106062185A (zh) * | 2014-04-24 | 2016-10-26 | 美天旎生物技术有限公司 | 用于自动生成遗传修饰的t细胞的方法 |
| CA3017170C (en) * | 2014-09-17 | 2021-03-23 | The Johns Hopkins University | Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells |
| ES2987570T3 (es) | 2014-11-05 | 2024-11-15 | Juno Therapeutics Inc | Métodos para la transducción y el procesamiento de células |
| AU2016249005B2 (en) | 2015-04-17 | 2022-06-16 | Novartis Ag | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
| EP3319631A4 (en) | 2015-07-08 | 2019-01-09 | American Gene Technologies International Inc. | HIV PREMUNICATION AND IMMUNOTHERAPY |
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