KR20210093232A - 유기용매와 세제가 없는 형질감염 적격 소포를 포함하는 조성물과 시스템 및 관련 방법 - Google Patents
유기용매와 세제가 없는 형질감염 적격 소포를 포함하는 조성물과 시스템 및 관련 방법 Download PDFInfo
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- KR20210093232A KR20210093232A KR1020217009987A KR20217009987A KR20210093232A KR 20210093232 A KR20210093232 A KR 20210093232A KR 1020217009987 A KR1020217009987 A KR 1020217009987A KR 20217009987 A KR20217009987 A KR 20217009987A KR 20210093232 A KR20210093232 A KR 20210093232A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862743116P | 2018-10-09 | 2018-10-09 | |
| US62/743,116 | 2018-10-09 | ||
| PCT/US2019/055472 WO2020077007A1 (en) | 2018-10-09 | 2019-10-09 | Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210093232A true KR20210093232A (ko) | 2021-07-27 |
Family
ID=70164385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217009987A Pending KR20210093232A (ko) | 2018-10-09 | 2019-10-09 | 유기용매와 세제가 없는 형질감염 적격 소포를 포함하는 조성물과 시스템 및 관련 방법 |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US11980673B2 (https=) |
| EP (2) | EP4379053A3 (https=) |
| JP (3) | JP7555123B2 (https=) |
| KR (1) | KR20210093232A (https=) |
| CN (2) | CN113166783B (https=) |
| AU (3) | AU2019359299B2 (https=) |
| BR (1) | BR112021006539A2 (https=) |
| CA (1) | CA3114699A1 (https=) |
| DK (1) | DK3864163T3 (https=) |
| EA (1) | EA202190688A1 (https=) |
| ES (1) | ES2982542T3 (https=) |
| FI (1) | FI3864163T3 (https=) |
| HR (1) | HRP20240586T1 (https=) |
| HU (1) | HUE066181T2 (https=) |
| IL (1) | IL282063A (https=) |
| PH (1) | PH12021550626A1 (https=) |
| PL (1) | PL3864163T3 (https=) |
| PT (1) | PT3864163T (https=) |
| RS (1) | RS65449B1 (https=) |
| WO (1) | WO2020077007A1 (https=) |
| ZA (1) | ZA202102238B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MA49421A (fr) | 2017-06-15 | 2020-04-22 | Modernatx Inc | Formulations d'arn |
| EP3675817A1 (en) | 2017-08-31 | 2020-07-08 | Modernatx, Inc. | Methods of making lipid nanoparticles |
| WO2020061457A1 (en) | 2018-09-20 | 2020-03-26 | Modernatx, Inc. | Preparation of lipid nanoparticles and methods of administration thereof |
| HRP20240586T1 (hr) | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| CN118697900A (zh) | 2019-01-31 | 2024-09-27 | 摩登纳特斯有限公司 | 制备脂质纳米颗粒的方法 |
| JP2023526284A (ja) * | 2020-05-15 | 2023-06-21 | トランスレイト バイオ, インコーポレイテッド | mRNA送達のための脂質ナノ粒子製剤 |
| EP4192432A1 (en) * | 2020-08-06 | 2023-06-14 | ModernaTX, Inc. | Methods of preparing lipid nanoparticles |
| CZ310613B6 (cs) | 2020-09-23 | 2026-01-28 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Lipidoidy pro transfekci nukleových kyselin a jejich použití |
| WO2022115645A1 (en) | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
| TW202237068A (zh) * | 2020-12-09 | 2022-10-01 | 美商建南德克公司 | 製備脂質奈米顆粒的高通量方法及其用途 |
| CZ310443B6 (cs) | 2021-07-19 | 2025-06-25 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| WO2023009421A1 (en) * | 2021-07-26 | 2023-02-02 | Modernatx, Inc. | Processes for preparing lipid nanoparticle compositions |
| US12589073B2 (en) * | 2021-11-11 | 2026-03-31 | Northwestern University | Leveraging lipid-protein interactions to engineer spatial organization in cell-free systems |
| US20250235559A1 (en) * | 2022-02-25 | 2025-07-24 | Incisive Genetics Inc. | Gene editing reporter system and guide rna and composition related thereto; composition and method for knocking out dna with more than two grnas; gene editing in the eye; and gene editing using base editors |
| CA3256897A1 (en) | 2022-05-25 | 2023-11-30 | Akagera Medicines, Inc. | Lipid nanoparticles for the administration of nucleic acids and their methods of use |
| US20240000966A1 (en) * | 2022-06-30 | 2024-01-04 | Life Technologies Corporation | Lipid Compositions For In Vivo Delivery |
| WO2025184543A1 (en) * | 2024-03-01 | 2025-09-04 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for delivery of therapeutic compounds |
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| US5776486A (en) | 1993-05-28 | 1998-07-07 | Aphios Corporation | Methods and apparatus for making liposomes containing hydrophobic drugs |
| US5981501A (en) * | 1995-06-07 | 1999-11-09 | Inex Pharmaceuticals Corp. | Methods for encapsulating plasmids in lipid bilayers |
| CA2227989A1 (en) | 1995-08-01 | 1997-02-13 | Karen Ophelia Hamilton | Liposomal oligonucleotide compositions |
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| US7262173B2 (en) | 1997-03-21 | 2007-08-28 | Georgetown University | Chemosensitizing with liposomes containing oligonucleotides |
| AU733310C (en) | 1997-05-14 | 2001-11-29 | University Of British Columbia, The | High efficiency encapsulation of charged therapeutic agents in lipid vesicles |
| US6110745A (en) | 1997-07-24 | 2000-08-29 | Inex Pharmaceuticals Corp. | Preparation of lipid-nucleic acid particles using a solvent extraction and direct hydration method |
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| US6693086B1 (en) | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
| US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
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| AU5905400A (en) | 1999-07-14 | 2001-02-05 | Board Of Regents, The University Of Texas System | Methods and compositions for delivery and retention of active agents to lymph nodes |
| US7094423B1 (en) | 1999-07-15 | 2006-08-22 | Inex Pharmaceuticals Corp. | Methods for preparation of lipid-encapsulated therapeutic agents |
| JP4554883B2 (ja) | 2000-10-04 | 2010-09-29 | 協和発酵キリン株式会社 | 脂質膜による微粒子の被覆方法 |
| US7713942B2 (en) | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
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| WO2002087541A1 (en) | 2001-04-30 | 2002-11-07 | Protiva Biotherapeutics Inc. | Lipid-based formulations for gene transfer |
| EP1441763A2 (en) | 2001-11-07 | 2004-08-04 | Inex Pharmaceuticals Corp. | Mucosal adjuvants comprising an oligonucleotide and a cationic lipid |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| CA2532228C (en) | 2003-07-16 | 2017-02-14 | Protiva Biotherapeutics, Inc. | Lipid encapsulated interfering rna |
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