KR20210072147A - 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 - Google Patents

개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Download PDF

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KR20210072147A
KR20210072147A KR1020217017654A KR20217017654A KR20210072147A KR 20210072147 A KR20210072147 A KR 20210072147A KR 1020217017654 A KR1020217017654 A KR 1020217017654A KR 20217017654 A KR20217017654 A KR 20217017654A KR 20210072147 A KR20210072147 A KR 20210072147A
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ala
leu
gly
mutation
glu
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Korean (ko)
Inventor
매튜 루드
나 트린
안드레아스 셔머
제이콥 가노
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게노마티카 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0108—Long-chain acyl-[acyl-carrier-protein] reductase (1.2.1.80)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fats And Perfumes (AREA)
KR1020217017654A 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Ceased KR20210072147A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361753273P 2013-01-16 2013-01-16
US61/753,273 2013-01-16
PCT/US2014/011859 WO2014113571A2 (en) 2013-01-16 2014-01-16 Acyl-acp reductase with improved properties
KR1020207004969A KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

Related Parent Applications (1)

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KR1020207004969A Division KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

Publications (1)

Publication Number Publication Date
KR20210072147A true KR20210072147A (ko) 2021-06-16

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KR1020217017654A Ceased KR20210072147A (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020177015121A Expired - Fee Related KR102082247B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020157021992A Active KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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KR1020177015121A Expired - Fee Related KR102082247B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020157021992A Active KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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US (6) US9683219B2 (enExample)
EP (3) EP2946009B1 (enExample)
JP (5) JP6063585B2 (enExample)
KR (4) KR20210072147A (enExample)
CN (3) CN109897834A (enExample)
AU (3) AU2014207522B2 (enExample)
BR (1) BR112015017005A2 (enExample)
CA (2) CA2898317C (enExample)
CO (1) CO7461134A2 (enExample)
ES (2) ES2600354T3 (enExample)
MX (2) MX356997B (enExample)
MY (1) MY167434A (enExample)
WO (1) WO2014113571A2 (enExample)

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CA2775390C (en) 2009-09-27 2021-06-29 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
CN109182238A (zh) 2012-08-10 2019-01-11 嘉吉有限公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
WO2014113571A2 (en) * 2013-01-16 2014-07-24 Ls9, Inc. Acyl-acp reductase with improved properties
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP6603658B2 (ja) 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
BR112017001105A2 (pt) * 2014-07-18 2018-07-24 REG Life Sciences, LLC produção microbiana de dióis graxos
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
CN111094558A (zh) 2017-04-03 2020-05-01 基因组股份公司 对产生中链脂肪酸衍生物具有改善的活性的硫酯酶变体
US12098168B2 (en) 2018-08-31 2024-09-24 Genomatica, Inc. XylR mutant for improved xylose utilization or improved co-utilization of glucose and xylose preliminary
EP3844269A4 (en) * 2018-08-31 2022-07-27 Genomatica, Inc. PRODUCTION OF NON-NATIVE MONOUNSATURATED FATTY ACIDS IN BACTERIA
EP4493683A1 (en) 2022-03-16 2025-01-22 Genomatica, Inc. Acyl-acp thioesterase variants and uses thereof

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Publication number Publication date
JP2017042170A (ja) 2017-03-02
US20200010813A1 (en) 2020-01-09
AU2019202790A1 (en) 2019-05-16
CA2898317A1 (en) 2014-07-24
JP2021006067A (ja) 2021-01-21
AU2014207522B2 (en) 2016-12-15
US20240117324A1 (en) 2024-04-11
US20170342388A1 (en) 2017-11-30
CA2898317C (en) 2022-03-01
EP3103867B1 (en) 2018-05-16
ES2675224T3 (es) 2018-07-09
CN105051189A (zh) 2015-11-11
JP7094343B2 (ja) 2022-07-01
US20220090028A1 (en) 2022-03-24
KR20170066694A (ko) 2017-06-14
BR112015017005A2 (pt) 2017-08-15
CN109897834A (zh) 2019-06-18
KR20150105471A (ko) 2015-09-16
KR101746040B1 (ko) 2017-06-13
US9683219B2 (en) 2017-06-20
WO2014113571A2 (en) 2014-07-24
JP2019141083A (ja) 2019-08-29
MY167434A (en) 2018-08-28
MX2015009138A (es) 2015-11-06
CN110387352A (zh) 2019-10-29
JP2016503663A (ja) 2016-02-08
WO2014113571A3 (en) 2014-11-13
AU2014207522A1 (en) 2015-05-07
US20160348080A1 (en) 2016-12-01
EP3385375A1 (en) 2018-10-10
EP2946009A2 (en) 2015-11-25
US20150361454A1 (en) 2015-12-17
KR102082247B1 (ko) 2020-02-28
AU2017200596A1 (en) 2017-02-23
MX356997B (es) 2018-06-22
EP3385375B1 (en) 2021-06-16
US11130944B2 (en) 2021-09-28
KR102265148B1 (ko) 2021-06-15
CA3143642A1 (en) 2014-07-24
JP6523393B2 (ja) 2019-05-29
US12173329B2 (en) 2024-12-24
CN105051189B (zh) 2019-08-06
US10208294B2 (en) 2019-02-19
AU2017200596B2 (en) 2019-01-24
JP2017209118A (ja) 2017-11-30
KR20200020998A (ko) 2020-02-26
US9873865B2 (en) 2018-01-23
ES2600354T3 (es) 2017-02-08
EP3103867A1 (en) 2016-12-14
JP6063585B2 (ja) 2017-01-18
JP6926143B2 (ja) 2021-08-25
CO7461134A2 (es) 2015-11-30
MX346830B (es) 2017-04-03
EP2946009B1 (en) 2016-07-27
JP6211162B2 (ja) 2017-10-11

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