KR20210070232A - 크로몰린 나트륨 및 이부프로펜의 분말화된 제형 - Google Patents

크로몰린 나트륨 및 이부프로펜의 분말화된 제형 Download PDF

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Publication number
KR20210070232A
KR20210070232A KR1020207004292A KR20207004292A KR20210070232A KR 20210070232 A KR20210070232 A KR 20210070232A KR 1020207004292 A KR1020207004292 A KR 1020207004292A KR 20207004292 A KR20207004292 A KR 20207004292A KR 20210070232 A KR20210070232 A KR 20210070232A
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Prior art keywords
ibuprofen
sodium
cromolin
sieve
composition
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Ceased
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KR1020207004292A
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English (en)
Korean (ko)
Inventor
데이비드 알. 엘마레
주안 비. 곤잘레즈
Original Assignee
아즈테라피즈 인코포레이티드
더 제너럴 하스피탈 코포레이션
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Publication of KR20210070232A publication Critical patent/KR20210070232A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020207004292A 2017-07-20 2017-12-12 크로몰린 나트륨 및 이부프로펜의 분말화된 제형 Ceased KR20210070232A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762534848P 2017-07-20 2017-07-20
US62/534,848 2017-07-20
PCT/US2017/065727 WO2019017995A1 (en) 2017-07-20 2017-12-12 FORMULATIONS OF CROMOLYNE SODIUM POWDER AND IBUPROFEN

Publications (1)

Publication Number Publication Date
KR20210070232A true KR20210070232A (ko) 2021-06-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207004292A Ceased KR20210070232A (ko) 2017-07-20 2017-12-12 크로몰린 나트륨 및 이부프로펜의 분말화된 제형

Country Status (9)

Country Link
US (3) US10561612B2 (enExample)
EP (1) EP3654946A4 (enExample)
JP (1) JP7202376B2 (enExample)
KR (1) KR20210070232A (enExample)
CN (1) CN111565711B (enExample)
AU (1) AU2017423862A1 (enExample)
CA (1) CA3070386A1 (enExample)
MX (1) MX2020000577A (enExample)
WO (1) WO2019017995A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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US20190240194A1 (en) 2016-08-31 2019-08-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
WO2020010049A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation POWDERED FORMULATIONS OF CROMOLYN SODIUM AND α-LACTOSE
CN113727736A (zh) 2018-12-10 2021-11-30 通用医疗公司 色甘酸酯及其用途
JP2023520580A (ja) 2020-04-06 2023-05-17 ザ ジェネラル ホスピタル コーポレイション コロナウイルス誘発炎症状態の処置方法

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Publication number Publication date
MX2020000577A (es) 2020-09-10
EP3654946A4 (en) 2021-04-21
WO2019017995A1 (en) 2019-01-24
US20210023010A1 (en) 2021-01-28
US10561612B2 (en) 2020-02-18
JP7202376B2 (ja) 2023-01-11
CN111565711B (zh) 2023-01-03
CN111565711A (zh) 2020-08-21
EP3654946A1 (en) 2020-05-27
US20190022006A1 (en) 2019-01-24
CA3070386A1 (en) 2019-01-24
JP2020528453A (ja) 2020-09-24
US20230248650A1 (en) 2023-08-10
AU2017423862A1 (en) 2020-02-06

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