KR20200113214A - Dnm2 발현의 조절제 - Google Patents
Dnm2 발현의 조절제 Download PDFInfo
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- KR20200113214A KR20200113214A KR1020207022337A KR20207022337A KR20200113214A KR 20200113214 A KR20200113214 A KR 20200113214A KR 1020207022337 A KR1020207022337 A KR 1020207022337A KR 20207022337 A KR20207022337 A KR 20207022337A KR 20200113214 A KR20200113214 A KR 20200113214A
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Classifications
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N2310/341—Gapmers, i.e. of the type ===---===
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862617411P | 2018-01-15 | 2018-01-15 | |
| US62/617,411 | 2018-01-15 | ||
| PCT/US2019/013689 WO2019140452A1 (en) | 2018-01-15 | 2019-01-15 | Modulators of dnm2 expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200113214A true KR20200113214A (ko) | 2020-10-06 |
Family
ID=65324590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207022337A Ceased KR20200113214A (ko) | 2018-01-15 | 2019-01-15 | Dnm2 발현의 조절제 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20200392510A1 (https=) |
| EP (1) | EP3740575A1 (https=) |
| JP (1) | JP2021511072A (https=) |
| KR (1) | KR20200113214A (https=) |
| CN (1) | CN111902537A (https=) |
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| US12312585B2 (en) * | 2020-02-14 | 2025-05-27 | University Of Massachusetts | Oligonucleotides targeting frataxin and related methods |
| US12275941B2 (en) | 2021-04-15 | 2025-04-15 | Research Institute At Nationwide Children's Hospital | Products and methods for inhibition of expression of dynamin-1 variants |
| EP4215614A1 (en) | 2022-01-24 | 2023-07-26 | Dynacure | Combination therapy for dystrophin-related diseases |
| EP4311546A1 (en) | 2022-07-26 | 2024-01-31 | Dynacure | Combination therapy for myopathies |
| CN121263524A (zh) * | 2023-05-04 | 2026-01-02 | 豪夫迈·罗氏有限公司 | 能够上调葡糖脑苷脂酶表达的寡核苷酸 |
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| WO2025085732A1 (en) * | 2023-10-18 | 2025-04-24 | Sarepta Therapeutics, Inc. | Humanized dnm2 mouse model generation, characterization and methods of use |
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| AU2019206731A1 (en) | 2020-07-30 |
| BR112020014425A2 (pt) | 2020-12-29 |
| CL2020001851A1 (es) | 2021-02-19 |
| EP3740575A1 (en) | 2020-11-25 |
| MA51645A (fr) | 2020-11-25 |
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