KR20180118784A - 경구 투여용 구상 흡착탄을 포함하는 정제 및 이의 제조 방법 - Google Patents

경구 투여용 구상 흡착탄을 포함하는 정제 및 이의 제조 방법 Download PDF

Info

Publication number
KR20180118784A
KR20180118784A KR1020187029091A KR20187029091A KR20180118784A KR 20180118784 A KR20180118784 A KR 20180118784A KR 1020187029091 A KR1020187029091 A KR 1020187029091A KR 20187029091 A KR20187029091 A KR 20187029091A KR 20180118784 A KR20180118784 A KR 20180118784A
Authority
KR
South Korea
Prior art keywords
tablets
additive
spherical
tablet
oral administration
Prior art date
Application number
KR1020187029091A
Other languages
English (en)
Korean (ko)
Inventor
요시키 마치
요헤이 코야
사이치 오노
마유 코니시
히로나오 시마다
Original Assignee
가부시끼가이샤 구레하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 가부시끼가이샤 구레하 filed Critical 가부시끼가이샤 구레하
Publication of KR20180118784A publication Critical patent/KR20180118784A/ko

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/44—Elemental carbon, e.g. charcoal, carbon black
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187029091A 2016-04-01 2017-03-29 경구 투여용 구상 흡착탄을 포함하는 정제 및 이의 제조 방법 KR20180118784A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2016-074580 2016-04-01
JP2016074580 2016-04-01
PCT/JP2017/013050 WO2017170764A1 (ja) 2016-04-01 2017-03-29 経口投与用球状吸着炭を含む錠剤及びその製造方法

Publications (1)

Publication Number Publication Date
KR20180118784A true KR20180118784A (ko) 2018-10-31

Family

ID=59964672

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187029091A KR20180118784A (ko) 2016-04-01 2017-03-29 경구 투여용 구상 흡착탄을 포함하는 정제 및 이의 제조 방법

Country Status (5)

Country Link
JP (1) JP6707126B2 (zh)
KR (1) KR20180118784A (zh)
CN (1) CN108883130B (zh)
TW (1) TWI701055B (zh)
WO (1) WO2017170764A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111408343B (zh) * 2019-01-08 2022-01-28 湖南农业大学 三维立体生物炭的制备方法及其在重金属吸附中的应用
JP7499054B2 (ja) 2020-04-03 2024-06-13 フタムラ化学株式会社 経口投与用錠剤型吸着剤
JP7438897B2 (ja) 2020-08-26 2024-02-27 フタムラ化学株式会社 経口投与用錠剤型吸着剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5595611A (en) * 1979-01-17 1980-07-21 Osamu Otsubo Mannan-coated activated carbon
EP0166315B1 (de) * 1984-06-19 1989-08-23 BASF Aktiengesellschaft Magensaftresistent überzogene zylindrische Pankreatin-Mikrotabletten
US6294198B1 (en) * 1999-08-24 2001-09-25 Purepac Pharmaceutical Co. Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same
JP2005187405A (ja) * 2003-12-25 2005-07-14 Lion Corp 尿酸値抑制剤、及びプリン体吸着剤
JP4875840B2 (ja) * 2004-07-30 2012-02-15 トーアエイヨー株式会社 経口投与用活性炭製剤
JP2007137802A (ja) * 2005-11-16 2007-06-07 Takeda Chem Ind Ltd 錠剤の製造法
CN101103997B (zh) * 2006-09-05 2011-02-02 河北长天药业有限公司 着色药用炭薄膜衣片剂制备方法
CN101543511A (zh) * 2008-03-26 2009-09-30 河北长天药业有限公司 含有药用炭和聚乙二醇的压制药物组合物
JP5415837B2 (ja) * 2009-06-12 2014-02-12 アサヒグループホールディングス株式会社 圧縮成形性に劣る粉末状の機能性物質から顆粒及び錠剤を製造する方法
KR101593287B1 (ko) * 2011-03-04 2016-02-11 가부시끼가이샤 구레하 정제형의 경구 투여용 조성물 및 그의 제조 방법
JP6310780B2 (ja) * 2013-06-12 2018-04-11 第一三共ヘルスケア株式会社 経口用組成物

Also Published As

Publication number Publication date
WO2017170764A1 (ja) 2017-10-05
JP6707126B2 (ja) 2020-06-10
CN108883130A (zh) 2018-11-23
JPWO2017170764A1 (ja) 2018-12-27
TWI701055B (zh) 2020-08-11
CN108883130B (zh) 2021-06-22
TW201735906A (zh) 2017-10-16

Similar Documents

Publication Publication Date Title
JP5701971B2 (ja) 錠剤型の経口投与用組成物及びその製造方法
KR20050089961A (ko) 유기 폴리머 물질과 결합된 무기 입자들을 포함하고 고형의망상형 매트릭스를 형성하는 약학적 부형제, 조성물, 그의제조 및 용도
JP2006506357A6 (ja) 有機高分子物質との組み合わせで無機粒子を含み、かつ固体の網目状マトリックスを形成する医薬賦形剤、その組成物、製造および使用
EP2327424A1 (en) Novel excipient for mannitol tableting
KR20180118784A (ko) 경구 투여용 구상 흡착탄을 포함하는 정제 및 이의 제조 방법
JP2023182650A (ja) 粒状組成物、粒状組成物の製造方法、および粒状組成物の溶出性改善方法
JP6430679B2 (ja) 経口投与用球状吸着炭を含む錠剤
CN106038584A (zh) 一种胶体果胶铋胶囊剂及其制备方法
CN103655501A (zh) 一种纳米布洛芬干粉与片剂及其制备方法
CN1864679A (zh) 一种复方岩白菜素分散片及其制备方法
WO2019012552A4 (en) Compositions of ferric organic compounds
CN1634045A (zh) 复方法莫替丁咀嚼片制备方法
KR101509489B1 (ko) 발사르탄을 함유하는 고형 경구제형의 제조 방법
JP6216408B2 (ja) 固体剤形で非常に難溶性の薬物を調製する方法
CN116531314A (zh) 一种难溶性药物纳米晶口服递送体系及其制备方法
WO2019012553A1 (en) PROCESS FOR THE PREPARATION OF COMPOSITIONS OF FERRIC ORGANIC COMPOUNDS
JPWO2005117920A1 (ja) 循環器機能障害因子除去剤
CN1444929A (zh) 黄藤素分散片及其制备方法

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application