KR20180094965A - 위장 괄약근 기능장애의 치료를 위한 sGC 자극제의 용도 - Google Patents
위장 괄약근 기능장애의 치료를 위한 sGC 자극제의 용도 Download PDFInfo
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- KR20180094965A KR20180094965A KR1020187019784A KR20187019784A KR20180094965A KR 20180094965 A KR20180094965 A KR 20180094965A KR 1020187019784 A KR1020187019784 A KR 1020187019784A KR 20187019784 A KR20187019784 A KR 20187019784A KR 20180094965 A KR20180094965 A KR 20180094965A
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- ring
- alkyl
- membered heterocyclic
- membered heteroaryl
- phenyl
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Landscapes
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| AU2015317823A1 (en) * | 2014-09-17 | 2017-03-23 | Ironwood Pharmaceuticals, Inc. | sGC stimulators |
| WO2017107052A1 (en) | 2015-12-22 | 2017-06-29 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase stimulators |
| MA46755A (fr) * | 2016-11-08 | 2021-06-02 | Cyclerion Therapeutics Inc | Stimulateurs de sgc |
| US11690828B2 (en) * | 2016-11-08 | 2023-07-04 | Cyclerion Therapeutics, Inc. | Treatment of CNS diseases with sGC stimulators |
| US20190381039A1 (en) * | 2016-12-13 | 2019-12-19 | Cyclerion Therapeutics, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF ESOPHAGEAL MOTILITY DISORDERS |
| AU2019301683B9 (en) * | 2018-07-11 | 2025-04-24 | Tisento Therapeutics Inc. | Use of sGC stimulators for the treatment of mitochondrial disorders |
| US20240342187A1 (en) * | 2021-06-14 | 2024-10-17 | Curtails Llc | Use of nep inhibitors for the treatment of gastrointestinal sphincter disorders |
| EP4512804A1 (en) * | 2022-04-20 | 2025-02-26 | Shanghai Zhimeng Biopharma, Inc. | Rho-associated protein kinase inhibitor and preparation and use thereof |
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| US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
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| DE19642255A1 (de) | 1996-10-14 | 1998-04-16 | Bayer Ag | Verwendung von 1-Benzyl-3-(substituierten-hetaryl) -kondensierten Pyrazol-Derivaten |
| EP0934311B1 (de) | 1996-10-14 | 2009-05-13 | Bayer HealthCare AG | Neue heterocyclylmethyl-substituierte pyrazolderivate und ihre verwendung in der behandlung von herz-kreislauf-erkrankungen |
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| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| US6451805B1 (en) | 1997-11-14 | 2002-09-17 | Bayer Aktiengesellschaft | Substituted pyrazole derivatives for the treatment of cardiocirculatory diseases |
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| DE19834045A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | (4-Amino-5-ethylpyrimidin-2-yl)-1-(2-fluorbenzyl)-1H-pyrazolo[3,4-b]pyridin |
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| DE19942809A1 (de) | 1999-09-08 | 2001-03-15 | Bayer Ag | Verfahren zur Herstellung substituierter Pyrimidinderivate |
| DE19943635A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften |
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| DE10054278A1 (de) | 2000-11-02 | 2002-05-08 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Osteoporose |
| DE10057751A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Carbamat-substituierte Pyrazolopyridinderivate |
| DE10057754A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Sulfonamid-substituierte Pyrazolopyridinderivate |
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| DE10132416A1 (de) | 2001-07-04 | 2003-01-16 | Bayer Ag | Neue Morpholin-überbrückte Pyrazolopyridinderivate |
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| DE10216145A1 (de) | 2002-04-12 | 2003-10-23 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom |
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| DE10222550A1 (de) | 2002-05-17 | 2003-11-27 | Bayer Ag | Substituierte Benzyl-pyrazolopyridine |
| DE10232571A1 (de) | 2002-07-18 | 2004-02-05 | Bayer Ag | 4-Aminosubstituierte Pyrimidinderivate |
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2016
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- 2016-12-13 MX MX2018007152A patent/MX2018007152A/es unknown
- 2016-12-13 EP EP16867373.9A patent/EP3389655A2/en not_active Withdrawn
- 2016-12-13 WO PCT/US2016/066357 patent/WO2017106175A2/en not_active Ceased
- 2016-12-13 US US16/061,992 patent/US20180344735A1/en not_active Abandoned
- 2016-12-13 AU AU2016371762A patent/AU2016371762A1/en not_active Abandoned
- 2016-12-13 EA EA201891416A patent/EA201891416A1/ru unknown
- 2016-12-13 KR KR1020187019784A patent/KR20180094965A/ko not_active Withdrawn
- 2016-12-13 CN CN201680078621.9A patent/CN108463224A/zh active Pending
- 2016-12-13 CA CA3006764A patent/CA3006764A1/en not_active Abandoned
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2018
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| EA201891416A1 (ru) | 2018-12-28 |
| MX2018007152A (es) | 2018-08-15 |
| WO2017106175A3 (en) | 2017-10-19 |
| CN108463224A (zh) | 2018-08-28 |
| CA3006764A1 (en) | 2017-06-22 |
| AU2016371762A1 (en) | 2018-06-21 |
| JP2019502686A (ja) | 2019-01-31 |
| EP3389655A2 (en) | 2018-10-24 |
| WO2017106175A2 (en) | 2017-06-22 |
| IL259639A (en) | 2018-07-31 |
| US20180344735A1 (en) | 2018-12-06 |
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