AU2016371762A1 - Use of sGC stimulators for the treatment of gastrointestinal sphincter dysfunction - Google Patents
Use of sGC stimulators for the treatment of gastrointestinal sphincter dysfunction Download PDFInfo
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- AU2016371762A1 AU2016371762A1 AU2016371762A AU2016371762A AU2016371762A1 AU 2016371762 A1 AU2016371762 A1 AU 2016371762A1 AU 2016371762 A AU2016371762 A AU 2016371762A AU 2016371762 A AU2016371762 A AU 2016371762A AU 2016371762 A1 AU2016371762 A1 AU 2016371762A1
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- membered heteroaryl
- membered heterocyclic
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Landscapes
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| PCT/US2016/066357 WO2017106175A2 (en) | 2015-12-14 | 2016-12-13 | USE OF sGC STIMULATORS FOR THE TREATMENT OF GASTROINTESTINAL SPHINCTER DYSFUNCTION |
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| WO2017107052A1 (en) | 2015-12-22 | 2017-06-29 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase stimulators |
| AU2017356887B2 (en) * | 2016-11-08 | 2022-06-30 | Cyclerion Therapeutics, Inc. | sGC stimulators |
| EP3538096B1 (en) * | 2016-11-08 | 2024-02-28 | Tisento Therapeutics Inc. | Treatment of cns diseases with sgc stimulators |
| WO2018111795A2 (en) * | 2016-12-13 | 2018-06-21 | Ironwood Pharmaceuticals, Inc. | Use of sgc stimulators for the treatment of esophageal motility disorders |
| US12220414B2 (en) * | 2018-07-11 | 2025-02-11 | Tisento Therapeutics Inc. | Use of sGC stimulators for the treatment of mitochondrial disorders |
| WO2022265984A1 (en) * | 2021-06-14 | 2022-12-22 | Curtails Llc | Use of nep inhibitors for the treatment of gastrointestinal sphincter disorders |
| JP2025515296A (ja) * | 2022-04-20 | 2025-05-14 | シャンハイ ジムン バイオファーマ，インコーポレーテッド | Ｒｈｏ関連プロテインキナーゼ阻害剤ならびにその調製および応用 |
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| GB8928043D0 (en) * | 1989-12-12 | 1990-02-14 | Pfizer Ltd | Muscarinic receptor antagonists |
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| US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| DE19642255A1 (de) | 1996-10-14 | 1998-04-16 | Bayer Ag | Verwendung von 1-Benzyl-3-(substituierten-hetaryl) -kondensierten Pyrazol-Derivaten |
| ATE431347T1 (de) | 1996-10-14 | 2009-05-15 | Bayer Healthcare Ag | Neue heterocyclylmethyl-substituierte pyrazolderivate und ihre verwendung in der behandlung von herz-kreislauf-erkrankungen |
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| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| US6451805B1 (en) | 1997-11-14 | 2002-09-17 | Bayer Aktiengesellschaft | Substituted pyrazole derivatives for the treatment of cardiocirculatory diseases |
| CZ302691B6 (cs) | 1998-07-08 | 2011-09-07 | Sanofi - Aventis Deutschland GmbH | N-Arylamidová sloucenina, zpusob její prípravy, farmaceutický prostredek tuto slouceninu obsahující, tato sloucenina pro použití jako aktivátor a pro použití k terapii nebo profylaxi |
| DE19830430A1 (de) | 1998-07-08 | 2000-01-13 | Hoechst Marion Roussel De Gmbh | Schwefelsubstituierte Sulfonylamino-carbonsäure-N-arylamide, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
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| DE19834045A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | (4-Amino-5-ethylpyrimidin-2-yl)-1-(2-fluorbenzyl)-1H-pyrazolo[3,4-b]pyridin |
| DE19834047A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituierte Pyrazolderivate |
| DE19846514A1 (de) | 1998-10-09 | 2000-04-20 | Bayer Ag | Neue Heterocyclyl-methyl-substituierte Pyrazole |
| GB9824310D0 (en) | 1998-11-05 | 1998-12-30 | Univ London | Activators of soluble guanylate cyclase |
| DE19920352A1 (de) | 1999-05-04 | 2000-11-09 | Bayer Ag | Substituiertes Pyrazolderivat |
| DE19942809A1 (de) | 1999-09-08 | 2001-03-15 | Bayer Ag | Verfahren zur Herstellung substituierter Pyrimidinderivate |
| DE19943635A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften |
| DE19962926A1 (de) | 1999-12-24 | 2001-06-28 | Bayer Ag | Verfahren zur Co-Mahlung von Stoffen und Lactose mittels Strahlmühlen |
| DE10021069A1 (de) | 2000-04-28 | 2001-10-31 | Bayer Ag | Substituiertes Pyrazolderivat |
| DE10054278A1 (de) | 2000-11-02 | 2002-05-08 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Osteoporose |
| AR031176A1 (es) | 2000-11-22 | 2003-09-10 | Bayer Ag | Nuevos derivados de pirazolpiridina sustituidos con piridina |
| DE10057754A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Sulfonamid-substituierte Pyrazolopyridinderivate |
| AU2002221827A1 (en) | 2000-11-22 | 2002-06-03 | Bayer Aktiengesellschaft | Novel lactame-substituted pyrazolopyridine derivatives |
| DE10057751A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Carbamat-substituierte Pyrazolopyridinderivate |
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| DE10122894A1 (de) | 2001-05-11 | 2002-11-14 | Bayer Ag | Neue Sulfonat-substituierte Pyrazolopyridinderivate |
| DE10132416A1 (de) | 2001-07-04 | 2003-01-16 | Bayer Ag | Neue Morpholin-überbrückte Pyrazolopyridinderivate |
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| DE10216145A1 (de) | 2002-04-12 | 2003-10-23 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom |
| DE10220570A1 (de) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| DE10222550A1 (de) | 2002-05-17 | 2003-11-27 | Bayer Ag | Substituierte Benzyl-pyrazolopyridine |
| DE10232571A1 (de) | 2002-07-18 | 2004-02-05 | Bayer Ag | 4-Aminosubstituierte Pyrimidinderivate |
| DE10232572A1 (de) | 2002-07-18 | 2004-02-05 | Bayer Ag | Neue 2,5-disubstituierte Pyrimidinderivate |
| DE10242941A1 (de) | 2002-09-16 | 2004-03-18 | Bayer Ag | Substituiertes Pyrazolderivat |
| DE10244810A1 (de) | 2002-09-26 | 2004-04-08 | Bayer Ag | Neue Morpholin-überbrückte Indazolderivate |
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-
2016
- 2016-12-13 KR KR1020187019784A patent/KR20180094965A/ko not_active Withdrawn
- 2016-12-13 CA CA3006764A patent/CA3006764A1/en not_active Abandoned
- 2016-12-13 WO PCT/US2016/066357 patent/WO2017106175A2/en not_active Ceased
- 2016-12-13 AU AU2016371762A patent/AU2016371762A1/en not_active Abandoned
- 2016-12-13 JP JP2018531178A patent/JP2019502686A/ja active Pending
- 2016-12-13 EP EP16867373.9A patent/EP3389655A2/en not_active Withdrawn
- 2016-12-13 EA EA201891416A patent/EA201891416A1/ru unknown
- 2016-12-13 US US16/061,992 patent/US20180344735A1/en not_active Abandoned
- 2016-12-13 MX MX2018007152A patent/MX2018007152A/es unknown
- 2016-12-13 CN CN201680078621.9A patent/CN108463224A/zh active Pending
-
2018
- 2018-05-28 IL IL259639A patent/IL259639A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3006764A1 (en) | 2017-06-22 |
| WO2017106175A3 (en) | 2017-10-19 |
| MX2018007152A (es) | 2018-08-15 |
| IL259639A (en) | 2018-07-31 |
| US20180344735A1 (en) | 2018-12-06 |
| JP2019502686A (ja) | 2019-01-31 |
| EA201891416A1 (ru) | 2018-12-28 |
| CN108463224A (zh) | 2018-08-28 |
| WO2017106175A2 (en) | 2017-06-22 |
| EP3389655A2 (en) | 2018-10-24 |
| KR20180094965A (ko) | 2018-08-24 |
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