KR20170072343A - Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법 - Google Patents

Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법 Download PDF

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KR20170072343A
KR20170072343A KR1020177014991A KR20177014991A KR20170072343A KR 20170072343 A KR20170072343 A KR 20170072343A KR 1020177014991 A KR1020177014991 A KR 1020177014991A KR 20177014991 A KR20177014991 A KR 20177014991A KR 20170072343 A KR20170072343 A KR 20170072343A
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amino acid
acid sequence
antibody
agent
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정 엠. 킴
제인 엘. 그로간
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제넨테크, 인크.
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • General Health & Medical Sciences (AREA)
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  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020177014991A 2014-11-06 2015-10-29 Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법 Withdrawn KR20170072343A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462076152P 2014-11-06 2014-11-06
US62/076,152 2014-11-06
PCT/US2015/058087 WO2016073282A1 (en) 2014-11-06 2015-10-29 Combination therapy comprising ox40 binding agonists and tigit inhibitors

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KR20170072343A true KR20170072343A (ko) 2017-06-26

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KR1020177014991A Withdrawn KR20170072343A (ko) 2014-11-06 2015-10-29 Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법

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US (3) US20160152720A1 (cg-RX-API-DMAC7.html)
EP (1) EP3215536A1 (cg-RX-API-DMAC7.html)
JP (1) JP2017534633A (cg-RX-API-DMAC7.html)
KR (1) KR20170072343A (cg-RX-API-DMAC7.html)
CN (1) CN107073126A (cg-RX-API-DMAC7.html)
AR (1) AR102553A1 (cg-RX-API-DMAC7.html)
AU (1) AU2015343494A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017008628A2 (cg-RX-API-DMAC7.html)
CA (1) CA2963974A1 (cg-RX-API-DMAC7.html)
IL (1) IL251618A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017005929A (cg-RX-API-DMAC7.html)
RU (1) RU2017119428A (cg-RX-API-DMAC7.html)
SG (1) SG11201703376QA (cg-RX-API-DMAC7.html)
TW (1) TW201628650A (cg-RX-API-DMAC7.html)
WO (1) WO2016073282A1 (cg-RX-API-DMAC7.html)

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