KR20160093012A - 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물 - Google Patents

암 치료를 위한 체크포인트 억제제 및 치료제의 배합물 Download PDF

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KR20160093012A
KR20160093012A KR1020167014867A KR20167014867A KR20160093012A KR 20160093012 A KR20160093012 A KR 20160093012A KR 1020167014867 A KR1020167014867 A KR 1020167014867A KR 20167014867 A KR20167014867 A KR 20167014867A KR 20160093012 A KR20160093012 A KR 20160093012A
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South Korea
Prior art keywords
cancer
cell
tumor
checkpoint inhibitor
cells
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Korean (ko)
Inventor
마르닉스 레오 보쉬
제임스 켈리 간제이
린다 에프. 파워스
린다 엠. 리아우
로버트 엠. 프린스
Original Assignee
코그네이트 바이오서비시즈, 인코포레이티드
레브이뮨, 인코포레이티드
더 리전트 오브 더 유니버시티 오브 캘리포니아
노쓰웨스트 바이오써라퓨틱스, 인크.
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Publication of KR20160093012A publication Critical patent/KR20160093012A/ko
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020167014867A 2013-11-05 2014-11-05 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물 Withdrawn KR20160093012A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361900355P 2013-11-05 2013-11-05
US201361900309P 2013-11-05 2013-11-05
US61/900,355 2013-11-05
US61/900,309 2013-11-05
PCT/US2014/064133 WO2015069770A1 (en) 2013-11-05 2014-11-05 Combinations of checkpoint inhibitors and therapeutics to treat cancer

Publications (1)

Publication Number Publication Date
KR20160093012A true KR20160093012A (ko) 2016-08-05

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KR1020167014867A Withdrawn KR20160093012A (ko) 2013-11-05 2014-11-05 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물

Country Status (14)

Country Link
US (4) US20150273033A1 (enExample)
EP (2) EP3065772B1 (enExample)
JP (1) JP2016540042A (enExample)
KR (1) KR20160093012A (enExample)
CN (1) CN105828834A (enExample)
AU (1) AU2014346852A1 (enExample)
BR (1) BR112016010224A2 (enExample)
EA (1) EA201690912A1 (enExample)
ES (1) ES2991853T3 (enExample)
HK (1) HK1232119A1 (enExample)
IL (3) IL292510A (enExample)
MX (2) MX2016005925A (enExample)
PH (1) PH12016500841A1 (enExample)
WO (1) WO2015069770A1 (enExample)

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KR20210022669A (ko) * 2018-06-19 2021-03-03 사이토베이션 에이에스 펩타이드를 사용하는 병용 요법
US11229668B2 (en) 2017-02-07 2022-01-25 Nantcell, Inc. Maximizing T-cell memory and compositions and methods therefor

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CR20160319A (es) 2013-12-12 2016-11-08 Jiangsu Hengrui Medicine Co Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
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CN107073090A (zh) * 2014-04-30 2017-08-18 哈佛学院董事会 结合的疫苗装置和杀死癌细胞的方法
JO3663B1 (ar) 2014-08-19 2020-08-27 Merck Sharp & Dohme الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
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KR20170132171A (ko) * 2015-02-26 2017-12-01 메르크 파텐트 게엠베하 암 치료를 위한 ｐｄ­１ ／ ｐｄ­ｌ１ 저해제
HK1249052A1 (zh) 2015-03-06 2018-10-26 BeyondSpring Pharmaceuticals Inc. 治疗与ras突变相关的癌症的方法
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MA42971A (fr) 2015-03-13 2018-08-15 Cytomx Therapeutics Inc Anticorps anti-pdl1, anticorps anti-pld1 activables, et leurs procédés d'utilisation
PT3291821T (pt) * 2015-05-07 2026-03-18 Baylor College Medicine Imunoterapêutica com células dendríticas
EP3292152A1 (en) 2015-05-07 2018-03-14 Agenus Inc. Anti-ox40 antibodies and methods of use thereof
WO2016187122A1 (en) * 2015-05-15 2016-11-24 University Of Iowa Research Foundation Methods for treating tumors in situ including intratumor injection of cytotoxic particles and immune checkpoint blockade therapy
KR102349677B1 (ko) 2015-05-28 2022-01-12 카이트 파마 인코포레이티드 T 세포 요법을 위해 환자를 컨디셔닝하는 방법
KR20230005428A (ko) * 2015-05-28 2023-01-09 카이트 파마 인코포레이티드 T 세포 요법을 위한 진단 방법
DK3303394T3 (da) 2015-05-29 2020-07-06 Agenus Inc Anti-ctla-4-antistoffer og fremgangsmåder til anvendelse deraf
KR102779525B1 (ko) * 2015-05-29 2025-03-12 다이나박스 테크놀로지 코퍼레이션 폐암을 치료하기 위한 폴리뉴클레오티드 Toll-유사 수용체 9 아고니스트의 폐내 투여
HK1253064A1 (zh) * 2015-06-01 2019-06-06 The University Of Chicago 通过操纵共生微生物菌群对癌症的治疗
RU2766890C2 (ru) 2015-06-16 2022-03-16 Мерк Патент Гмбх Комбинированные способы лечения антагонистами pd-l1
KR20180023968A (ko) * 2015-07-02 2018-03-07 셀진 코포레이션 혈액암 및 충실성 종양의 치료를 위한 병용 요법
EP3334726B1 (en) 2015-07-13 2022-03-16 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
MX383464B (es) 2015-07-13 2025-03-14 Cytomx Therapeutics Inc Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos.
CA2991628C (en) * 2015-07-16 2020-04-07 Bioxcel Therapeutics, Inc. A novel approach for treatment of cancer using immunomodulation
MX2017016844A (es) 2015-07-16 2018-08-15 Biokine Therapeutics Ltd Composiciones y procedimientos para tratar cancer.
US10842763B2 (en) 2015-07-31 2020-11-24 The Johns Hopkins University Methods for cancer and immunotherapy using prodrugs of glutamine analogs
WO2017023793A2 (en) 2015-07-31 2017-02-09 The Johns Hopkins University Methods for cancer and immunotherapy using glutamine analogues, including don
HRP20231163T1 (hr) 2015-07-31 2024-03-15 The Johns Hopkins University Prolijekovi glutaminskih analoga
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