KR20160024853A - 당뇨병 치료를 위한 주사형 나노-네트워크 겔 - Google Patents
당뇨병 치료를 위한 주사형 나노-네트워크 겔 Download PDFInfo
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- KR20160024853A KR20160024853A KR1020157034126A KR20157034126A KR20160024853A KR 20160024853 A KR20160024853 A KR 20160024853A KR 1020157034126 A KR1020157034126 A KR 1020157034126A KR 20157034126 A KR20157034126 A KR 20157034126A KR 20160024853 A KR20160024853 A KR 20160024853A
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- Prior art keywords
- insulin
- particles
- glucose
- agent
- acid
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K9/51—Nanocapsules; Nanoparticles
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| US61/864,069 | 2013-08-09 | ||
| PCT/US2014/035927 WO2014179344A1 (en) | 2013-04-30 | 2014-04-29 | Injectable nano-network gels for diabetes treatment |
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| WO2014153114A1 (en) * | 2013-03-14 | 2014-09-25 | Fred Hutchinson Cancer Research Center | Compositions and methods to modify cells for therapeutic objectives |
| JP2017538728A (ja) * | 2014-12-19 | 2017-12-28 | ケミン、インダストリーズ、インコーポレーテッドＫｅｍｉｎ Ｉｎｄｕｓｔｒｉｅｓ， Ｉｎｃ． | イオントフォレシスを用いた生物活性分子の眼内送達 |
| CN104740641B (zh) * | 2015-04-08 | 2019-02-01 | 烟台大学 | 一种糖敏感的缓控释微球组合物及其制备方法 |
| BR112017022535A2 (pt) * | 2015-04-21 | 2018-07-10 | Univ North Carolina State | sistema de liberação de insulina responsivo à glicose usando nanocompósitos sensíveis à hipóxia. |
| CN113730605A (zh) * | 2016-07-21 | 2021-12-03 | 波士顿科学国际有限公司 | 可注射组合物 |
| US11351230B2 (en) | 2016-11-07 | 2022-06-07 | North Carolina State University | Patch loaded with dual-sensitive vesicles for enhanced glucose-responsive insulin delivery |
| WO2018106696A1 (en) * | 2016-12-05 | 2018-06-14 | North Carolina State University | Core-shell microneedle devices and uses thereof |
| CN106668840B (zh) * | 2017-02-10 | 2020-02-14 | 南通大学 | 一种胰岛素控释药物及其制备方法与应用 |
| CN111343970A (zh) * | 2017-09-13 | 2020-06-26 | 北卡罗莱纳州立大学 | 微针贴片局部诱导脂肪组织褐变治疗肥胖症 |
| EP3713594A4 (en) | 2017-11-21 | 2021-11-03 | North Carolina State University | LOADABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRA-FAST REACTION |
| EP3735262A4 (en) * | 2018-01-03 | 2021-09-29 | Penn State Research Foundation | GLUCOSE OXIDASE COMPOSITIONS USED AS AN ANTI-CONVULSIVER IN NEWBORNS |
| CN111195238A (zh) * | 2018-10-31 | 2020-05-26 | 南方医科大学 | 一种用于胰岛素口服递送的聚电解质复合物 |
| WO2020219880A2 (en) * | 2019-04-25 | 2020-10-29 | Massachusetts Institute Of Technology | Cyclodextrin supramolecular scaffolds and uses thereof |
| CN115350267B (zh) * | 2022-07-19 | 2025-01-14 | 深圳大学 | 一种级联催化型纳米治疗剂及其制备方法和应用 |
| CN116474162B (zh) * | 2023-04-28 | 2024-08-16 | 吉林大学 | 一种用于糖尿病慢性创伤修复的自修复水凝胶的制备方法 |
| WO2025024243A1 (en) * | 2023-07-21 | 2025-01-30 | Massachusetts Institute Of Technology | Readily soluble and thermostable glucagon formulations and delivery for mini-dosing and closed-loop prophylactic treatment of hypoglycemia |
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| AU3360197A (en) * | 1996-07-01 | 1998-01-21 | Universiteit Utrecht | Hydrolysable hydrogels for controlled release |
| AU2003301064A1 (en) * | 2002-12-17 | 2004-07-14 | Massachusetts Institute Of Technology | Stimuli-responsive systems for controlled drug delivery |
| WO2006088473A2 (en) * | 2004-04-23 | 2006-08-24 | Panduranga Rao Koritala | Microcapsules and nanocapsules for the transmucosal delivery of therapeutic and diagnostic agents |
| EP1595534A1 (en) * | 2004-05-13 | 2005-11-16 | Universiteit Utrecht Holding B.V. | Gel composition comprising charged polymers |
| TWI394580B (zh) * | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
| US20110189299A1 (en) * | 2008-07-01 | 2011-08-04 | Nitto Denko Corporation | Pharmaceutical composition containing surface-coated microparticles |
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| EP2991673A1 (en) | 2016-03-09 |
| RU2015151135A (ru) | 2017-06-02 |
| HK1222546A1 (zh) | 2017-07-07 |
| JP2016517885A (ja) | 2016-06-20 |
| EP2991673A4 (en) | 2016-12-21 |
| BR112015027561A8 (pt) | 2019-12-24 |
| US20160067190A1 (en) | 2016-03-10 |
| AU2014260024A1 (en) | 2015-11-19 |
| MX2015015079A (es) | 2016-07-05 |
| HK1221415A1 (zh) | 2017-06-02 |
| BR112015027561A2 (pt) | 2017-07-25 |
| CN105813652A (zh) | 2016-07-27 |
| AU2014260024B2 (en) | 2016-09-15 |
| WO2014179344A1 (en) | 2014-11-06 |
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