KR20160013110A - B-세포 cll/림프종 11a(bcl11a)의 올리고뉴클레오티드 조절제 및 이의 용도 - Google Patents

B-세포 cll/림프종 11a(bcl11a)의 올리고뉴클레오티드 조절제 및 이의 용도 Download PDF

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KR20160013110A
KR20160013110A KR1020157036075A KR20157036075A KR20160013110A KR 20160013110 A KR20160013110 A KR 20160013110A KR 1020157036075 A KR1020157036075 A KR 1020157036075A KR 20157036075 A KR20157036075 A KR 20157036075A KR 20160013110 A KR20160013110 A KR 20160013110A
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메이 헤티오른
닐스 피스커 닐센
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로슈 이노베이션 센터 코펜하겐 에이/에스
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KR1020157036075A 2013-05-24 2014-05-26 B-세포 cll/림프종 11a(bcl11a)의 올리고뉴클레오티드 조절제 및 이의 용도 Ceased KR20160013110A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361827484P 2013-05-24 2013-05-24
US61/827,484 2013-05-24
PCT/EP2014/060813 WO2014188001A1 (en) 2013-05-24 2014-05-26 Oligonucleotide modulators of b-cell cll/lymphoma 11a (bcl11a) and uses thereof

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KR20160013110A true KR20160013110A (ko) 2016-02-03

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US (1) US20160130582A1 (https=)
EP (1) EP3004352B1 (https=)
JP (1) JP2016520310A (https=)
KR (1) KR20160013110A (https=)
CN (1) CN105247052A (https=)
BR (1) BR112015029327A2 (https=)
CA (1) CA2907694A1 (https=)
DK (1) DK3004352T3 (https=)
HK (1) HK1213595A1 (https=)
MX (1) MX363846B (https=)
RU (1) RU2015155332A (https=)
WO (1) WO2014188001A1 (https=)

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CN102282155B (zh) 2008-12-02 2017-06-09 日本波涛生命科学公司 磷原子修饰的核酸的合成方法
RU2612521C2 (ru) 2009-07-06 2017-03-09 Онтории, Инк. Новые пролекарства нуклеиновых кислот и способы их применения
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
CN103796657B (zh) 2011-07-19 2017-07-11 波涛生命科学有限公司 合成官能化核酸的方法
PL2872485T3 (pl) 2012-07-13 2021-05-31 Wave Life Sciences Ltd. Asymetryczna grupa pomocnicza
KR102213609B1 (ko) 2012-07-13 2021-02-08 웨이브 라이프 사이언시스 리미티드 키랄 제어
JPWO2015108047A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
JPWO2015108048A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
BR112016016400A2 (pt) 2014-01-16 2017-10-03 Wave Life Sciences Ltd Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
WO2017184082A1 (en) * 2016-04-22 2017-10-26 Nanyang Technological University A lymphocyte permeating chimeric oligonucleotide, methods and uses thereof
US11957718B2 (en) 2016-12-22 2024-04-16 University Of Maryland, Baltimore Methods for generating multipotent stem cells from tonsillar biopsies
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EP3880819A2 (en) 2018-11-13 2021-09-22 Lipigon Pharmaceuticals AB Angptl4 oligonucleotides influencing the regulation of the fatty acid metabolism
CN114903992B (zh) * 2022-04-18 2024-01-16 南通大学 转录因子bcl11a在制备施万细胞调控药物中的应用
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods

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US6617442B1 (en) 1999-09-30 2003-09-09 Isis Pharmaceuticals, Inc. Human Rnase H1 and oligonucleotide compositions thereof
WO2004046160A2 (en) 2002-11-18 2004-06-03 Santaris Pharma A/S Amino-lna, thio-lna and alpha-l-oxy-ln
WO2007031091A2 (en) 2005-09-15 2007-03-22 Santaris Pharma A/S Rna antagonist compounds for the modulation of p21 ras expression
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JP2009536222A (ja) 2006-05-05 2009-10-08 アイシス ファーマシューティカルズ, インコーポレーテッド Pcsk9の発現を調節するための化合物および方法
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DK3004352T3 (da) 2017-11-27
CN105247052A (zh) 2016-01-13
MX363846B (es) 2019-04-05
US20160130582A1 (en) 2016-05-12
BR112015029327A2 (pt) 2017-09-19
RU2015155332A (ru) 2017-06-27
MX2015015564A (es) 2016-02-05
WO2014188001A1 (en) 2014-11-27
EP3004352B1 (en) 2017-09-27
CA2907694A1 (en) 2014-11-27
HK1213595A1 (zh) 2016-07-08
EP3004352A1 (en) 2016-04-13
JP2016520310A (ja) 2016-07-14

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