KR20150032537A - 2,2-디플루오로에틸아민의 알킬화에 의한 2,2-디플루오로에틸아민 유도체의 제조 방법 - Google Patents
2,2-디플루오로에틸아민의 알킬화에 의한 2,2-디플루오로에틸아민 유도체의 제조 방법 Download PDFInfo
- Publication number
- KR20150032537A KR20150032537A KR20147036103A KR20147036103A KR20150032537A KR 20150032537 A KR20150032537 A KR 20150032537A KR 20147036103 A KR20147036103 A KR 20147036103A KR 20147036103 A KR20147036103 A KR 20147036103A KR 20150032537 A KR20150032537 A KR 20150032537A
- Authority
- KR
- South Korea
- Prior art keywords
- difluoroethylamine
- chlorine
- formula
- fluorine
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- SKCNYHLTRZIINA-UHFFFAOYSA-N ClCc(cc1)cnc1Cl Chemical compound ClCc(cc1)cnc1Cl SKCNYHLTRZIINA-UHFFFAOYSA-N 0.000 description 1
- QDQGMLOVCICKPV-UHFFFAOYSA-N FC(CNCc(cn1)ccc1Cl)F Chemical compound FC(CNCc(cn1)ccc1Cl)F QDQGMLOVCICKPV-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12174277.9 | 2012-06-29 | ||
| EP12174277 | 2012-06-29 | ||
| PCT/EP2013/063116 WO2014001245A1 (de) | 2012-06-29 | 2013-06-24 | Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung von 2,2-difluorethylamin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20150032537A true KR20150032537A (ko) | 2015-03-26 |
Family
ID=48670571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20147036103A Ceased KR20150032537A (ko) | 2012-06-29 | 2013-06-24 | 2,2-디플루오로에틸아민의 알킬화에 의한 2,2-디플루오로에틸아민 유도체의 제조 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9376389B2 (https=) |
| EP (1) | EP2867208B1 (https=) |
| JP (1) | JP6175136B2 (https=) |
| KR (1) | KR20150032537A (https=) |
| CN (1) | CN104379564B (https=) |
| BR (1) | BR112014032479B1 (https=) |
| DK (1) | DK2867208T3 (https=) |
| ES (1) | ES2603287T3 (https=) |
| IL (1) | IL236257A (https=) |
| IN (1) | IN2014DN10440A (https=) |
| MX (1) | MX361289B (https=) |
| TW (1) | TWI593677B (https=) |
| WO (1) | WO2014001245A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6533233B2 (ja) * | 2014-03-21 | 2019-06-19 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | ２，２−ジフルオロエチルアミンをアルキル化することによりｎ−［（６−クロロピリジノ−３−イル）メチル］−２，２−ジフルオロエタン−１−アミンを調製する方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904676D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Ab | Novel compounds |
| DE102006015467A1 (de) * | 2006-03-31 | 2007-10-04 | Bayer Cropscience Ag | Substituierte Enaminocarbonylverbindungen |
| JP4821849B2 (ja) | 2006-04-10 | 2011-11-24 | 株式会社村田製作所 | 複合基板及び複合基板の製造方法 |
| DE102006033572A1 (de) * | 2006-07-20 | 2008-01-24 | Bayer Cropscience Ag | N'-Cyano-N-halogenalkyl-imidamid Derivate |
| EP2039684A1 (de) * | 2007-09-18 | 2009-03-25 | Bayer CropScience AG | Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung |
| KR101565391B1 (ko) | 2007-09-18 | 2015-11-03 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 아미드 수소화에 의한 2,2-디플루오로에틸아민 유도체의 제조방법 |
| EP2230231A1 (de) * | 2009-03-16 | 2010-09-22 | Bayer CropScience AG | Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung |
| EP2582673B1 (de) * | 2010-06-15 | 2014-08-06 | Bayer Intellectual Property GmbH | Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung mit 2,2- difluor-1-halogenethanen |
| WO2012062740A1 (de) * | 2010-11-12 | 2012-05-18 | Bayer Cropscience Ag | Verfahren zur herstellung von 2,2-difluorethylamin-derivaten ausgehend von n-(2,2-difluorethyl)prop-2-en-1-amin |
-
2013
- 2013-06-24 CN CN201380033732.4A patent/CN104379564B/zh active Active
- 2013-06-24 WO PCT/EP2013/063116 patent/WO2014001245A1/de not_active Ceased
- 2013-06-24 JP JP2015519021A patent/JP6175136B2/ja active Active
- 2013-06-24 EP EP13730578.5A patent/EP2867208B1/de active Active
- 2013-06-24 IN IN10440DEN2014 patent/IN2014DN10440A/en unknown
- 2013-06-24 DK DK13730578.5T patent/DK2867208T3/en active
- 2013-06-24 US US14/411,173 patent/US9376389B2/en active Active
- 2013-06-24 KR KR20147036103A patent/KR20150032537A/ko not_active Ceased
- 2013-06-24 ES ES13730578.5T patent/ES2603287T3/es active Active
- 2013-06-24 BR BR112014032479-4A patent/BR112014032479B1/pt active IP Right Grant
- 2013-06-24 MX MX2014015622A patent/MX361289B/es active IP Right Grant
- 2013-06-28 TW TW102123118A patent/TWI593677B/zh not_active IP Right Cessation
-
2014
- 2014-12-15 IL IL236257A patent/IL236257A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN104379564A (zh) | 2015-02-25 |
| IN2014DN10440A (https=) | 2015-08-21 |
| JP2015522574A (ja) | 2015-08-06 |
| JP6175136B2 (ja) | 2017-08-02 |
| ES2603287T3 (es) | 2017-02-24 |
| BR112014032479A2 (pt) | 2017-06-27 |
| EP2867208A1 (de) | 2015-05-06 |
| BR112014032479B1 (pt) | 2020-03-10 |
| IL236257A (en) | 2016-11-30 |
| DK2867208T3 (en) | 2016-12-05 |
| MX2014015622A (es) | 2015-03-20 |
| EP2867208B1 (de) | 2016-08-24 |
| CN104379564B (zh) | 2016-08-24 |
| WO2014001245A1 (de) | 2014-01-03 |
| IL236257A0 (en) | 2015-02-26 |
| MX361289B (es) | 2018-12-03 |
| TWI593677B (zh) | 2017-08-01 |
| TW201408639A (zh) | 2014-03-01 |
| US20150322011A1 (en) | 2015-11-12 |
| US9376389B2 (en) | 2016-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20141223 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20180622 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20190718 Patent event code: PE09021S01D |
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| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20190922 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20190718 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |