MX361289B - Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina. - Google Patents

Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina.

Info

Publication number
MX361289B
MX361289B MX2014015622A MX2014015622A MX361289B MX 361289 B MX361289 B MX 361289B MX 2014015622 A MX2014015622 A MX 2014015622A MX 2014015622 A MX2014015622 A MX 2014015622A MX 361289 B MX361289 B MX 361289B
Authority
MX
Mexico
Prior art keywords
difluoroethylamine
preparing
alkylating
derivatives
formula
Prior art date
Application number
MX2014015622A
Other languages
English (en)
Other versions
MX2014015622A (es
Inventor
Norbert Lui
Christian Funke
Rafael Warsitz
Albert Schnatterer
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2014015622A publication Critical patent/MX2014015622A/es
Publication of MX361289B publication Critical patent/MX361289B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Un procedimiento para preparar una 2,2-difluoroetilamina de fórmula (III) en el que se hace reaccionar la 2,2-difluoroetilamina de formula (I) con un haluro de fórmula (II) en presencia de una base nitrogenada terciaria: (ver Fórmulas) donde, en las fórmulas (II) y (III), Hal y A se definen como se indica en la descripción.
MX2014015622A 2012-06-29 2013-06-24 Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina. MX361289B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12174277 2012-06-29
PCT/EP2013/063116 WO2014001245A1 (de) 2012-06-29 2013-06-24 Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung von 2,2-difluorethylamin

Publications (2)

Publication Number Publication Date
MX2014015622A MX2014015622A (es) 2015-03-20
MX361289B true MX361289B (es) 2018-12-03

Family

ID=48670571

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014015622A MX361289B (es) 2012-06-29 2013-06-24 Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina.

Country Status (13)

Country Link
US (1) US9376389B2 (es)
EP (1) EP2867208B1 (es)
JP (1) JP6175136B2 (es)
KR (1) KR20150032537A (es)
CN (1) CN104379564B (es)
BR (1) BR112014032479B1 (es)
DK (1) DK2867208T3 (es)
ES (1) ES2603287T3 (es)
IL (1) IL236257A (es)
IN (1) IN2014DN10440A (es)
MX (1) MX361289B (es)
TW (1) TWI593677B (es)
WO (1) WO2014001245A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6533233B2 (ja) * 2014-03-21 2019-06-19 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ２，２−ジフルオロエチルアミンをアルキル化することによりｎ−［（６−クロロピリジノ−３−イル）メチル］−２，２−ジフルオロエタン−１−アミンを調製する方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904676D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
DE102006015467A1 (de) * 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
WO2007116544A1 (ja) 2006-04-10 2007-10-18 Murata Manufacturing Co., Ltd. 複合基板及び複合基板の製造方法
DE102006033572A1 (de) * 2006-07-20 2008-01-24 Bayer Cropscience Ag N'-Cyano-N-halogenalkyl-imidamid Derivate
KR101565391B1 (ko) * 2007-09-18 2015-11-03 바이엘 크롭사이언스 악티엔게젤샤프트 아미드 수소화에 의한 2,2-디플루오로에틸아민 유도체의 제조방법
EP2039684A1 (de) * 2007-09-18 2009-03-25 Bayer CropScience AG Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung
EP2230231A1 (de) * 2009-03-16 2010-09-22 Bayer CropScience AG Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung
EP2582673B1 (de) * 2010-06-15 2014-08-06 Bayer Intellectual Property GmbH Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung mit 2,2- difluor-1-halogenethanen
CN103313969A (zh) * 2010-11-12 2013-09-18 拜耳知识产权有限责任公司 用于由n-(2，2-二氟乙基)丙-2-烯-1-胺起始制备2，2-二氟乙基胺衍生物的方法

Also Published As

Publication number Publication date
CN104379564A (zh) 2015-02-25
WO2014001245A1 (de) 2014-01-03
MX2014015622A (es) 2015-03-20
IL236257A0 (en) 2015-02-26
IL236257A (en) 2016-11-30
JP6175136B2 (ja) 2017-08-02
ES2603287T3 (es) 2017-02-24
US9376389B2 (en) 2016-06-28
IN2014DN10440A (es) 2015-08-21
JP2015522574A (ja) 2015-08-06
DK2867208T3 (en) 2016-12-05
KR20150032537A (ko) 2015-03-26
EP2867208B1 (de) 2016-08-24
EP2867208A1 (de) 2015-05-06
US20150322011A1 (en) 2015-11-12
TWI593677B (zh) 2017-08-01
BR112014032479B1 (pt) 2020-03-10
TW201408639A (zh) 2014-03-01
BR112014032479A2 (pt) 2017-06-27
CN104379564B (zh) 2016-08-24

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