MX361289B - Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina. - Google Patents
Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina.Info
- Publication number
- MX361289B MX361289B MX2014015622A MX2014015622A MX361289B MX 361289 B MX361289 B MX 361289B MX 2014015622 A MX2014015622 A MX 2014015622A MX 2014015622 A MX2014015622 A MX 2014015622A MX 361289 B MX361289 B MX 361289B
- Authority
- MX
- Mexico
- Prior art keywords
- difluoroethylamine
- preparing
- alkylating
- derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Un procedimiento para preparar una 2,2-difluoroetilamina de fórmula (III) en el que se hace reaccionar la 2,2-difluoroetilamina de formula (I) con un haluro de fórmula (II) en presencia de una base nitrogenada terciaria: (ver Fórmulas) donde, en las fórmulas (II) y (III), Hal y A se definen como se indica en la descripción.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12174277 | 2012-06-29 | ||
PCT/EP2013/063116 WO2014001245A1 (de) | 2012-06-29 | 2013-06-24 | Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung von 2,2-difluorethylamin |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014015622A MX2014015622A (es) | 2015-03-20 |
MX361289B true MX361289B (es) | 2018-12-03 |
Family
ID=48670571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014015622A MX361289B (es) | 2012-06-29 | 2013-06-24 | Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina. |
Country Status (13)
Country | Link |
---|---|
US (1) | US9376389B2 (es) |
EP (1) | EP2867208B1 (es) |
JP (1) | JP6175136B2 (es) |
KR (1) | KR20150032537A (es) |
CN (1) | CN104379564B (es) |
BR (1) | BR112014032479B1 (es) |
DK (1) | DK2867208T3 (es) |
ES (1) | ES2603287T3 (es) |
IL (1) | IL236257A (es) |
IN (1) | IN2014DN10440A (es) |
MX (1) | MX361289B (es) |
TW (1) | TWI593677B (es) |
WO (1) | WO2014001245A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6533233B2 (ja) * | 2014-03-21 | 2019-06-19 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 2,2−ジフルオロエチルアミンをアルキル化することによりn−[(6−クロロピリジノ−3−イル)メチル]−2,2−ジフルオロエタン−1−アミンを調製する方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9904676D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Ab | Novel compounds |
DE102006015467A1 (de) * | 2006-03-31 | 2007-10-04 | Bayer Cropscience Ag | Substituierte Enaminocarbonylverbindungen |
WO2007116544A1 (ja) | 2006-04-10 | 2007-10-18 | Murata Manufacturing Co., Ltd. | 複合基板及び複合基板の製造方法 |
DE102006033572A1 (de) * | 2006-07-20 | 2008-01-24 | Bayer Cropscience Ag | N'-Cyano-N-halogenalkyl-imidamid Derivate |
KR101565391B1 (ko) * | 2007-09-18 | 2015-11-03 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 아미드 수소화에 의한 2,2-디플루오로에틸아민 유도체의 제조방법 |
EP2039684A1 (de) * | 2007-09-18 | 2009-03-25 | Bayer CropScience AG | Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung |
EP2230231A1 (de) * | 2009-03-16 | 2010-09-22 | Bayer CropScience AG | Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung |
EP2582673B1 (de) * | 2010-06-15 | 2014-08-06 | Bayer Intellectual Property GmbH | Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch alkylierung mit 2,2- difluor-1-halogenethanen |
CN103313969A (zh) * | 2010-11-12 | 2013-09-18 | 拜耳知识产权有限责任公司 | 用于由n-(2,2-二氟乙基)丙-2-烯-1-胺起始制备2,2-二氟乙基胺衍生物的方法 |
-
2013
- 2013-06-24 US US14/411,173 patent/US9376389B2/en active Active
- 2013-06-24 MX MX2014015622A patent/MX361289B/es active IP Right Grant
- 2013-06-24 KR KR20147036103A patent/KR20150032537A/ko not_active Application Discontinuation
- 2013-06-24 ES ES13730578.5T patent/ES2603287T3/es active Active
- 2013-06-24 WO PCT/EP2013/063116 patent/WO2014001245A1/de active Application Filing
- 2013-06-24 IN IN10440DEN2014 patent/IN2014DN10440A/en unknown
- 2013-06-24 BR BR112014032479-4A patent/BR112014032479B1/pt active IP Right Grant
- 2013-06-24 EP EP13730578.5A patent/EP2867208B1/de active Active
- 2013-06-24 DK DK13730578.5T patent/DK2867208T3/en active
- 2013-06-24 CN CN201380033732.4A patent/CN104379564B/zh active Active
- 2013-06-24 JP JP2015519021A patent/JP6175136B2/ja active Active
- 2013-06-28 TW TW102123118A patent/TWI593677B/zh not_active IP Right Cessation
-
2014
- 2014-12-15 IL IL236257A patent/IL236257A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CN104379564A (zh) | 2015-02-25 |
WO2014001245A1 (de) | 2014-01-03 |
MX2014015622A (es) | 2015-03-20 |
IL236257A0 (en) | 2015-02-26 |
IL236257A (en) | 2016-11-30 |
JP6175136B2 (ja) | 2017-08-02 |
ES2603287T3 (es) | 2017-02-24 |
US9376389B2 (en) | 2016-06-28 |
IN2014DN10440A (es) | 2015-08-21 |
JP2015522574A (ja) | 2015-08-06 |
DK2867208T3 (en) | 2016-12-05 |
KR20150032537A (ko) | 2015-03-26 |
EP2867208B1 (de) | 2016-08-24 |
EP2867208A1 (de) | 2015-05-06 |
US20150322011A1 (en) | 2015-11-12 |
TWI593677B (zh) | 2017-08-01 |
BR112014032479B1 (pt) | 2020-03-10 |
TW201408639A (zh) | 2014-03-01 |
BR112014032479A2 (pt) | 2017-06-27 |
CN104379564B (zh) | 2016-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA113643C2 (xx) | N-цикліламіди як нематоциди | |
MX353553B (es) | Metodo para producir derivados de 4,4-difluoro-3,4-dihidroisoquino lina. | |
MY163187A (en) | Novel imidazo-oxazine compound or salt thereof | |
MX351513B (es) | Compuesto de alquinilbenceno 3,5-disustituido y sales del mismo. | |
IN2012DE00621A (es) | ||
IN2012DE00620A (es) | ||
PH12015501807B1 (en) | Vortioxetine manufacturing process | |
IN2015DN00446A (es) | ||
MX349214B (es) | Proceso para la fabricacion de benzoxazinonas. | |
MX2017017022A (es) | Metodo para la sintesis de derivados de rapamicina. | |
MX2016000390A (es) | Proceso para fabricar haloacetamidas. | |
MY165487A (en) | Process for preparing a polyol ether | |
IN2014DN09053A (es) | ||
PH12016501704B1 (en) | Method for producing 2-acyliminopyridine derivative | |
SA518391413B1 (ar) | عملية تحضير وتبلر لليوزيمينول | |
IN2015DN02877A (es) | ||
GB2523674A (en) | Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof | |
MX361998B (es) | Procedimiento de preparacion de derivados de acido 4-haloalquil-3-mercapto-2 sustituido-hidroxibenzoico. | |
MY160625A (en) | Process for preparing pan-cdk inhibitors of the formula(i), and intermediates in the preparation | |
MX2012014796A (es) | Proceso para preparar 4-hidroxipiridinas. | |
IN2012DN02000A (es) | ||
MX361289B (es) | Procedimiento para preparar derivados de 2,2-difluoroetilamina por alquilacion de 2,2-difluoroetilamina. | |
MX2016000487A (es) | Piridina-2-carboxamidas como nematicidas. | |
JO3189B1 (ar) | طريقة جديدة لتخليق (e2) -3- (3, 4- داي ميثوكسي فينيل)بروب-2 - يننيتريل واستخدامها لتخليق ايفابرادين والاملاح المضافة منها مع حمض مقبول صيدلانيا | |
PH12014501760A1 (en) | Method for stereoselective synthesis of 1,4-protected 9-hydroxy-5-oxo-1,4-diaza-spiro[5.5]undecanes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |