KR20140146181A - 특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르 - Google Patents

특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르 Download PDF

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KR20140146181A
KR20140146181A KR1020147031594A KR20147031594A KR20140146181A KR 20140146181 A KR20140146181 A KR 20140146181A KR 1020147031594 A KR1020147031594 A KR 1020147031594A KR 20147031594 A KR20147031594 A KR 20147031594A KR 20140146181 A KR20140146181 A KR 20140146181A
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South Korea
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group
cellulose ether
esterified cellulose
hydroxyalkyl
methyl
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Ceased
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KR1020147031594A
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Korean (ko)
Inventor
로베르트 엘. 슈미트
로베르트 엘. 샘러
마이놀프 브락하겐
올리버 페터만
롤란트 아덴
니콜라스 에스. 그라스만
스티븐 제이. 기요되
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다우 글로벌 테크놀로지스 엘엘씨
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Application filed by 다우 글로벌 테크놀로지스 엘엘씨 filed Critical 다우 글로벌 테크놀로지스 엘엘씨
Publication of KR20140146181A publication Critical patent/KR20140146181A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/193—Mixed ethers, i.e. ethers with two or more different etherifying groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00—Preparation of cellulose ether-esters

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
KR1020147031594A 2012-04-11 2012-10-24 특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르 Ceased KR20140146181A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261622754P 2012-04-11 2012-04-11
US61/622,754 2012-04-11
PCT/US2012/061586 WO2013154607A1 (en) 2012-04-11 2012-10-24 Esterified cellulose ethers having a specific substituent distribution

Publications (1)

Publication Number Publication Date
KR20140146181A true KR20140146181A (ko) 2014-12-24

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KR1020147031594A Ceased KR20140146181A (ko) 2012-04-11 2012-10-24 특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르

Country Status (6)

Country Link
US (1) US9320799B2 (enExample)
EP (1) EP2836205B1 (enExample)
JP (1) JP6133969B2 (enExample)
KR (1) KR20140146181A (enExample)
CN (1) CN104427979B (enExample)
WO (1) WO2013154607A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240046783A (ko) * 2021-08-26 2024-04-09 뉴트리션 ＆ 바이오사이언시즈 유에스에이 1, 엘엘씨 신규 하이드록시알킬 메틸셀룰로스 및 이의 용도

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2961775B1 (en) 2013-03-01 2020-04-08 Hercules LLC Pharmaceutical compositions with enhanced performance and improved processability
JP6267239B2 (ja) * 2013-03-07 2018-01-24 ダウ グローバル テクノロジーズ エルエルシー 極めて低粘度の新規エステル化セルロースエーテル
KR102194967B1 (ko) * 2013-03-07 2020-12-24 다우 글로벌 테크놀로지스 엘엘씨 초고분자량의 신규한 에스테르화된 셀룰로스 에테르
JP6306691B2 (ja) * 2013-05-14 2018-04-04 ダウ グローバル テクノロジーズ エルエルシー ジカルボン酸を用いたエステル化セルロースエーテル
KR102286952B1 (ko) * 2013-12-31 2021-08-09 롯데정밀화학 주식회사 입도분포가 조절된 히드록시프로필 메틸셀룰로오스 아세테이트 숙시네이트(hpmcas) 입자의 제조방법 및 hpmcas 분말
US10759873B2 (en) 2014-02-20 2020-09-01 Dow Global Technologies Llc Esterified cellulose ethers of high molecular weight and homogeneity
EP3145498B1 (en) * 2014-05-20 2020-03-04 Dow Global Technologies LLC Dispersion comprising a partially neutralized esterified cellulose ether
EP3186285B1 (en) * 2014-08-27 2022-04-13 Nutrition & Biosciences USA 1, LLC Esterified cellulose ethers of low acetone-insoluble content
JP6203702B2 (ja) 2014-11-18 2017-09-27 信越化学工業株式会社 ヒプロメロース酢酸エステルコハク酸エステルを用いたスプレードライ用溶液及び固体分散体の製造方法
US20180071396A1 (en) * 2015-03-16 2018-03-15 Dow Global Technologies Llc Aqueous solution of an esterified cellulose ether
MX2017011091A (es) * 2015-03-16 2017-11-10 Dow Global Technologies Llc Proceso para preparar un eter de celulosa esterificado en presencia de un acido carboxilico alifatico.
EP3270971B1 (en) * 2015-03-16 2019-01-09 Dow Global Technologies LLC Water-soluble esterified cellulose ethers having a low degree of neutralization
JP6356923B2 (ja) * 2015-03-16 2018-07-11 ダウ グローバル テクノロジーズ エルエルシー 水溶性エステル化セルロースエーテル
WO2016148976A1 (en) * 2015-03-16 2016-09-22 Dow Global Technologies Llc Gelling esterified cellulose ethers
JP6725534B2 (ja) * 2015-05-15 2020-07-22 ダウ グローバル テクノロジーズ エルエルシー 極めて高い分子量及び低い粘度のエステル化セルロースエーテルの生成プロセス
BR112017025103B1 (pt) * 2015-06-05 2022-05-10 Nutrition & Biosciences Usa 1, Llc Composição em pó
EP3303406B1 (en) 2015-06-05 2019-06-26 Dow Global Technologies LLC Cellulose ether powders
KR20180056668A (ko) * 2015-09-24 2018-05-29 다우 글로벌 테크놀로지스 엘엘씨 아세트산과 반응 촉매의 존재하에서 셀룰로오스 에테르의 에스테르를 제조하기 위한 방법
BR112018005463A2 (pt) * 2015-10-02 2018-10-09 Dow Global Technologies Llc composição aquosa compreendendo éter de celulose esterificado disperso
US9884922B2 (en) * 2016-03-11 2018-02-06 Shin-Etsu Chemical Co., Ltd. Hypromellose acetate succinate, method for producing the same and composition containing the same
GB201609222D0 (en) 2016-05-25 2016-07-06 F2G Ltd Pharmaceutical formulation
WO2018170060A1 (en) * 2017-03-17 2018-09-20 Dow Global Technologies Llc Process for recovering an esterified cellulose ether from a reaction product mixture
WO2019036123A1 (en) * 2017-08-16 2019-02-21 Dow Global Technologies Llc PROCESS FOR THE CONTROLLED PREPARATION OF LOW MOLECULAR WEIGHT CELLULOSE ETHER
EP3897728A1 (en) * 2018-12-18 2021-10-27 DDP Specialty Electronic Materials US, Inc. A sustained release composition comprising a hydroxyalkyl methylcellulose
US11819503B2 (en) 2019-04-23 2023-11-21 F2G Ltd Method of treating coccidioides infection
JP7128782B2 (ja) * 2019-08-09 2022-08-31 信越化学工業株式会社 エアゾール食品用組成物、ヒドロキシプロピルメチルセルロース及びヒドロキシプロピルメチルセルロースの製造方法
CN112704671B (zh) * 2020-12-28 2022-04-19 普洛药业股份有限公司 一种阿莫西林克拉维酸钾胶囊及其制备方法
EP4387732A4 (en) 2021-08-19 2025-09-03 Phenom Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF SARS-CoV-2
CN114805787B (zh) * 2022-02-24 2023-09-12 南京林业大学 一种纤维素基聚醚多元醇脂肪酸酯增塑剂及其制备方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435027A (en) 1965-12-13 1969-03-25 Hercules Inc Cellulose ether-esters and process
US4226981A (en) 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
DE2917104A1 (de) 1979-04-27 1980-11-06 Hoechst Ag Verfahren zur viskositaetserniedrigung von celluloseethern durch ozon und seine verwendung
US4365060A (en) 1979-04-28 1982-12-21 Shin-Etsu Chemical Co. Ltd. Enterosoluble capsules
JPS6225101A (ja) 1985-07-24 1987-02-03 Shin Etsu Chem Co Ltd 低重合度セルロ−スエ−テルの製造方法
JPS6281402A (ja) 1985-10-07 1987-04-14 Shin Etsu Chem Co Ltd セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法
JP2916238B2 (ja) * 1990-10-16 1999-07-05 旭化成工業株式会社 アルキルセルロースの製造方法
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
JP3002916B2 (ja) * 1991-10-29 2000-01-24 ダイセル化学工業株式会社 セルロース混合エーテルの製造法
JP2872951B2 (ja) * 1995-11-07 1999-03-24 第一工業製薬株式会社 カルボキシメチルセルロースナトリウム塩
JP3996653B2 (ja) * 1996-01-26 2007-10-24 信越化学工業株式会社 置換度分布が制御されたヒドロキシプロピルセルロース
US6261218B1 (en) 1998-12-01 2001-07-17 The Dow Chemical Company Process and apparatus for making low molecular weight cellulose ethers
DE10141680B4 (de) 2001-08-25 2004-02-26 Clariant Gmbh Verfahren zur Herstellung niederviskoser Celluloseether durch sauer-oxidativen Abbau von gemahlenen und getrockneten Celluloseethern
WO2005115330A2 (en) 2004-05-28 2005-12-08 Pfizer Products Inc. Pharmaceutical compositions with enhanced performance
JP2011074113A (ja) * 2009-09-29 2011-04-14 Toray Ind Inc セルロース混合エステルおよびその製造方法
BR112012031667A2 (pt) 2010-06-14 2016-11-08 Dow Global Technologies Llc composição
WO2015047762A1 (en) 2013-09-25 2015-04-02 Dow Global Technologies Llc Composition for application to a mucosa comprising a cellulose ether

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240046783A (ko) * 2021-08-26 2024-04-09 뉴트리션 ＆ 바이오사이언시즈 유에스에이 1, 엘엘씨 신규 하이드록시알킬 메틸셀룰로스 및 이의 용도

Also Published As

Publication number Publication date
EP2836205A1 (en) 2015-02-18
JP6133969B2 (ja) 2017-05-24
CN104427979A (zh) 2015-03-18
WO2013154607A1 (en) 2013-10-17
US9320799B2 (en) 2016-04-26
CN104427979B (zh) 2018-02-16
US20150065547A1 (en) 2015-03-05
EP2836205B1 (en) 2016-10-19
JP2015521209A (ja) 2015-07-27

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