KR20130014227A - 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법 - Google Patents

신규한 α-글루코실 스테비오사이드 및 이의 제조 방법 Download PDF

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Publication number
KR20130014227A
KR20130014227A KR1020110076211A KR20110076211A KR20130014227A KR 20130014227 A KR20130014227 A KR 20130014227A KR 1020110076211 A KR1020110076211 A KR 1020110076211A KR 20110076211 A KR20110076211 A KR 20110076211A KR 20130014227 A KR20130014227 A KR 20130014227A
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South Korea
Prior art keywords
stevioside
glucosyl
microorganism
leuconostoc
alpha
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KR1020110076211A
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English (en)
Korean (ko)
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이우송
김영민
노문철
류영배
박수진
김중수
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한국생명공학연구원
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Priority to KR1020110076211A priority Critical patent/KR20130014227A/ko
Priority to PCT/KR2012/006070 priority patent/WO2013019050A2/fr
Publication of KR20130014227A publication Critical patent/KR20130014227A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/16—Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01005—Dextransucrase (2.4.1.5)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
KR1020110076211A 2011-07-29 2011-07-29 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법 KR20130014227A (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020110076211A KR20130014227A (ko) 2011-07-29 2011-07-29 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법
PCT/KR2012/006070 WO2013019050A2 (fr) 2011-07-29 2012-07-30 Nouvel α-glycosyl stévioside et son procédé de préparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020110076211A KR20130014227A (ko) 2011-07-29 2011-07-29 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법

Publications (1)

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KR20130014227A true KR20130014227A (ko) 2013-02-07

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KR1020110076211A KR20130014227A (ko) 2011-07-29 2011-07-29 신규한 α-글루코실 스테비오사이드 및 이의 제조 방법

Country Status (2)

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KR (1) KR20130014227A (fr)
WO (1) WO2013019050A2 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018093196A1 (fr) * 2016-11-17 2018-05-24 서울대학교산학협력단 Procédé de synthèse de glycoside stéviosidique utilisant des souches modifiées appartenant au genre leuconostoc et nouveau glycoside stéviosidique ainsi préparé
KR20180055735A (ko) * 2016-11-17 2018-05-25 서울대학교산학협력단 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체
KR102167849B1 (ko) * 2019-12-20 2020-10-21 전남대학교산학협력단 알파-1,6 당전이 효소를 활용한 글루코실 스테비오사이드 제조방법
KR20200143612A (ko) * 2019-06-14 2020-12-24 씨제이제일제당 (주) 포도당 전이 효소를 포함하는 포도당 전이 스테비올 배당체 생산용 조성물 및 이를 이용한 포도당 전이 스테비올 배당체 제조방법
KR20210114359A (ko) * 2018-12-10 2021-09-23 서울대학교산학협력단 유산균 균주를 이용하여 제조된 올리고당을 포함하는 난수용성 물질의 수용액 가용화 조성물
KR20210114899A (ko) * 2017-12-15 2021-09-24 씨제이제일제당 (주) 락토바실러스 말리를 이용하여 포도당전이 스테비올 배당체를 제조하는 방법
CN113507842A (zh) * 2019-03-14 2021-10-15 Cj第一制糖株式会社 包含转糖基化甜菊苷和转糖基化瑞鲍迪甙a的组合物
JP2021533729A (ja) * 2018-08-22 2021-12-09 フイルメニツヒ ソシエテ アノニムFirmenich Sa テルペングリコシド誘導体およびその使用
JP2022519030A (ja) * 2019-06-14 2022-03-18 シージェイ チェイルジェダン コーポレーション 甘味素材組成物およびその製造方法
KR102431101B1 (ko) * 2021-08-25 2022-08-09 서울대학교산학협력단 감미가 개선된 스테비오사이드 당전이체와 당알코올 또는 설탕의 혼합 감미료를 포함하는 음료 조성물

Families Citing this family (18)

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BR122021005283B1 (pt) 2010-06-02 2022-02-22 Evolva, Inc Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
KR102114493B1 (ko) 2011-08-08 2020-05-26 에볼바 에스아 스테비올 글리코시드의 재조합 생산
SG11201505597SA (en) * 2013-02-06 2015-08-28 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
KR20150128705A (ko) 2013-02-11 2015-11-18 에볼바 에스아 재조합 숙주에서 스테비올 글리코시드의 효율적인 생성
JP2017528125A (ja) 2014-08-11 2017-09-28 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの産生
CA2960693A1 (fr) 2014-09-09 2016-03-17 Evolva Sa Production de glycosides de steviol dans des hotes de recombinaison
CA2973674A1 (fr) 2015-01-30 2016-08-04 Evolva Sa Production de glycosides de steviol dans des hotes de recombinaison
BR112017019290A2 (pt) * 2015-03-10 2018-05-02 Univ Groningen métodos de modificação enzimática dos glicosídeos de esteviol, glicosídeos de esteviol modificados obtidos deste modo e a sua utilização como edulcorantes
EP3271457B1 (fr) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransférases
AU2016307066A1 (en) 2015-08-07 2018-02-08 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2017178632A1 (fr) 2016-04-13 2017-10-19 Evolva Sa Production de glycosides de stéviol dans des hôtes recombinants
US10815514B2 (en) 2016-05-16 2020-10-27 Evolva Sa Production of steviol glycosides in recombinant hosts
CN110100006A (zh) 2016-11-07 2019-08-06 埃沃尔瓦公司 重组宿主中甜菊糖苷的生产
JP2021514607A (ja) 2018-02-26 2021-06-17 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ グルコシル化テルペングリコシド、テルペングリコシドおよびシクロデキストリンを含む組成物
JP2022501308A (ja) 2018-09-29 2022-01-06 フイルメニツヒ ソシエテ アノニムFirmenich Sa テルペングリコシド誘導体およびその使用
EP3781583A1 (fr) 2018-09-29 2021-02-24 Firmenich SA Dérivés de glycosides terpéniques et leurs utilisations
CN113430185B (zh) * 2021-07-29 2023-03-21 黑龙江大学 一种乳酸菌葡聚糖蔗糖酶的分离纯化方法
WO2023066457A1 (fr) * 2021-10-19 2023-04-27 Symrise Ag Glucosides de rubusoside

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US4219571A (en) * 1978-06-15 1980-08-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing a sweetener
US20090324793A1 (en) * 2008-06-26 2009-12-31 Diamond Nutricentical, Inc. Method of impoving taste of natural sweetener and composition thereof
KR101091138B1 (ko) * 2009-03-26 2011-12-09 한국생명공학연구원 류코노스톡 락티스로부터 유래된 글루칸수크라제 및 그 제조방법
KR101073990B1 (ko) * 2009-08-19 2011-10-17 한국생명공학연구원 글루칸수크라제를 이용한 아스코르브산 ２­글루코시드의 생산방법

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018093196A1 (fr) * 2016-11-17 2018-05-24 서울대학교산학협력단 Procédé de synthèse de glycoside stéviosidique utilisant des souches modifiées appartenant au genre leuconostoc et nouveau glycoside stéviosidique ainsi préparé
KR20180055735A (ko) * 2016-11-17 2018-05-25 서울대학교산학협력단 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체
KR20210114899A (ko) * 2017-12-15 2021-09-24 씨제이제일제당 (주) 락토바실러스 말리를 이용하여 포도당전이 스테비올 배당체를 제조하는 방법
JP2021533729A (ja) * 2018-08-22 2021-12-09 フイルメニツヒ ソシエテ アノニムFirmenich Sa テルペングリコシド誘導体およびその使用
KR20210114359A (ko) * 2018-12-10 2021-09-23 서울대학교산학협력단 유산균 균주를 이용하여 제조된 올리고당을 포함하는 난수용성 물질의 수용액 가용화 조성물
CN113507842A (zh) * 2019-03-14 2021-10-15 Cj第一制糖株式会社 包含转糖基化甜菊苷和转糖基化瑞鲍迪甙a的组合物
KR20200143612A (ko) * 2019-06-14 2020-12-24 씨제이제일제당 (주) 포도당 전이 효소를 포함하는 포도당 전이 스테비올 배당체 생산용 조성물 및 이를 이용한 포도당 전이 스테비올 배당체 제조방법
JP2022519030A (ja) * 2019-06-14 2022-03-18 シージェイ チェイルジェダン コーポレーション 甘味素材組成物およびその製造方法
KR102167849B1 (ko) * 2019-12-20 2020-10-21 전남대학교산학협력단 알파-1,6 당전이 효소를 활용한 글루코실 스테비오사이드 제조방법
KR102431101B1 (ko) * 2021-08-25 2022-08-09 서울대학교산학협력단 감미가 개선된 스테비오사이드 당전이체와 당알코올 또는 설탕의 혼합 감미료를 포함하는 음료 조성물

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